proglumide-3780 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the proglumide-3780 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACPP acid phosphatase, prostate
ACSL5 acyl-CoA synthetase long-chain family member 5
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADGRL3 adhesion G protein-coupled receptor L3
ADRA1A adrenoceptor alpha 1A
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOX15B arachidonate 15-lipoxygenase, type B
ASTN1 astrotactin 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAIAP3 BAI1-associated protein 3
BBC3 BCL2 binding component 3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BFSP1 beaded filament structural protein 1, filensin
BLZF1 basic leucine zipper nuclear factor 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTG2 BTG family, member 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAPZB capping protein (actin filament) muscle Z-line, beta
CCL21 chemokine (C-C motif) ligand 21
CD33 CD33 molecule
CDC14B cell division cycle 14B
CDC42 cell division cycle 42
CLDN9 claudin 9
CPB1 carboxypeptidase B1 (tissue)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CREBZF CREB/ATF bZIP transcription factor
CXCR3 chemokine (C-X-C motif) receptor 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYTH1 cytohesin 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPF1 D4, zinc and double PHD fingers family 1
EGFL7 EGF-like-domain, multiple 7
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHB2 EPH receptor B2
FGF22 fibroblast growth factor 22
FLJ22184
FSCN3 fascin actin-bundling protein 3, testicular
FUBP1 far upstream element (FUSE) binding protein 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GRB7 growth factor receptor-bound protein 7
GRTP1 growth hormone regulated TBC protein 1
GYPB glycophorin B (MNS blood group)
HEATR6 HEAT repeat containing 6
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
ING4 inhibitor of growth family, member 4
KIAA1654 KIAA1654 protein
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLK3 kallikrein-related peptidase 3
LAMA2 laminin, alpha 2
LRRN2 leucine rich repeat neuronal 2
LTB4R leukotriene B4 receptor
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MEOX1 mesenchyme homeobox 1
MLN motilin
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MPPE1 metallophosphoesterase 1
MRC2 mannose receptor, C type 2
MXD4 MAX dimerization protein 4
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NF1 neurofibromin 1
NLRP3 NLR family, pyrin domain containing 3
NPPA natriuretic peptide A
NRP2 neuropilin 2
PCDH9 protocadherin 9
PDE10A phosphodiesterase 10A
PDE4C phosphodiesterase 4C, cAMP-specific
PML promyelocytic leukemia
PNMA3 paraneoplastic Ma antigen 3
PRB1 proline-rich protein BstNI subfamily 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RNF208 ring finger protein 208
SDS serine dehydratase
SERHL2 serine hydrolase-like 2
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMAD6 SMAD family member 6
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYT11 synaptotagmin XI
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D22B TBC1 domain family, member 22B
TBX21 T-box 21
TLE4 transducin-like enhancer of split 4
TRIM10 tripartite motif containing 10
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
TULP2 tubby like protein 2
UBOX5 U-box domain containing 5
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
ZIC3 Zic family member 3
ZNF117 zinc finger protein 117
ZNF235 zinc finger protein 235
ZNF280A zinc finger protein 280A
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADGRL2 adhesion G protein-coupled receptor L2
AKAP5 A kinase (PRKA) anchor protein 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMC4 armadillo repeat containing 4
ATAD5 ATPase family, AAA domain containing 5
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BIRC7 baculoviral IAP repeat containing 7
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CA11 carbonic anhydrase XI
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CBX8 chromobox homolog 8
CDH7 cadherin 7, type 2
CIDEC cell death-inducing DFFA-like effector c
CPA4 carboxypeptidase A4
CSRNP3 cysteine-serine-rich nuclear protein 3
CYTH3 cytohesin 3
DCAF4 DDB1 and CUL4 associated factor 4
DEPTOR DEP domain containing MTOR-interacting protein
DPF3 D4, zinc and double PHD fingers, family 3
ECM1 extracellular matrix protein 1
FBXO31 F-box protein 31
FGL1 fibrinogen-like 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GALT galactose-1-phosphate uridylyltransferase
GREM1 gremlin 1, DAN family BMP antagonist
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2I general transcription factor IIi
HHAT hedgehog acyltransferase
HIST1H2AI histone cluster 1, H2ai
HIST1H3F histone cluster 1, H3f
IDI2-AS1 IDI2 antisense RNA 1
IL17RB interleukin 17 receptor B
IPO8 importin 8
KCTD15 potassium channel tetramerization domain containing 15
KDM5C lysine (K)-specific demethylase 5C
KRT37 keratin 37, type I
LINC00472 long intergenic non-protein coding RNA 472
LNPEP leucyl/cystinyl aminopeptidase
LRP5L low density lipoprotein receptor-related protein 5-like
LY86 lymphocyte antigen 86
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGEF1 melanoma antigen family F1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MCOLN3 mucolipin 3
MMP2 matrix metallopeptidase 2
MRPL41 mitochondrial ribosomal protein L41
NELL2 NEL-like 2 (chicken)
NGF nerve growth factor (beta polypeptide)
NOL12 nucleolar protein 12
OGDHL oxoglutarate dehydrogenase-like
OVOL1 ovo-like zinc finger 1
PADI1 peptidyl arginine deiminase, type I
PALM paralemmin
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRR14L proline rich 14-like
PRR15L proline rich 15-like
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RANBP17 RAN binding protein 17
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RPGRIP1L RPGRIP1-like
RPL10L ribosomal protein L10-like
SAYSD1 SAYSVFN motif domain containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SENP7 SUMO1/sentrin specific peptidase 7
SERGEF secretion regulating guanine nucleotide exchange factor
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC22A14 solute carrier family 22, member 14
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
STX1A syntaxin 1A (brain)
STXBP5L syntaxin binding protein 5-like
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TXK TXK tyrosine kinase
VASP vasodilator-stimulated phosphoprotein
VNN1 vanin 1
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZBED8 zinc finger, BED-type containing 8
ZNF140 zinc finger protein 140
ZNF141 zinc finger protein 141
ZNF334 zinc finger protein 334
ZNF480 zinc finger protein 480
ZNF492 zinc finger protein 492
ZNF528 zinc finger protein 528
ZNF702P zinc finger protein 702, pseudogene
ZNF76 zinc finger protein 76