| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the proglumide-4337 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATF7 | activating transcription factor 7 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BCL2 | B-cell CLL/lymphoma 2 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCDC121 | coiled-coil domain containing 121 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CORO7 | coronin 7 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYTH4 | cytohesin 4 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DICER1 | dicer 1, ribonuclease type III |
| DKFZP434C153 | DKFZP434C153 protein |
| DLX2 | distal-less homeobox 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FRMD8 | FERM domain containing 8 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GOLGA8A | golgin A8 family, member A |
| GPR17 | G protein-coupled receptor 17 |
| GPR182 | G protein-coupled receptor 182 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAP1 | huntingtin-associated protein 1 |
| HIST1H1E | histone cluster 1, H1e |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IFFO1 | intermediate filament family orphan 1 |
| ING2 | inhibitor of growth family, member 2 |
| INSL4 | insulin-like 4 (placenta) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KALRN | kalirin, RhoGEF kinase |
| KRT37 | keratin 37, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| LOC647070 | uncharacterized LOC647070 |
| MAP4 | microtubule-associated protein 4 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MECOM | MDS1 and EVI1 complex locus |
| MED18 | mediator complex subunit 18 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MRAS | muscle RAS oncogene homolog |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| N4BP1 | NEDD4 binding protein 1 |
| NCOR2 | nuclear receptor corepressor 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OLFM1 | olfactomedin 1 |
| OLFML2B | olfactomedin-like 2B |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PER2 | period circadian clock 2 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PHOX2B | paired-like homeobox 2b |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| POU2F2 | POU class 2 homeobox 2 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| RAB36 | RAB36, member RAS oncogene family |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAB6B | RAB6B, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RGS4 | regulator of G-protein signaling 4 |
| RGSL1 | regulator of G-protein signaling like 1 |
| RHOH | ras homolog family member H |
| RPL35A | ribosomal protein L35a |
| RUNX1 | runt-related transcription factor 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TBCD | tubulin folding cofactor D |
| TMEM206 | transmembrane protein 206 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRA | T cell receptor alpha locus |
| TRIM3 | tripartite motif containing 3 |
| UBQLN4 | ubiquilin 4 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF287 | zinc finger protein 287 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARSB | arylsulfatase B |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CASZ1 | castor zinc finger 1 |
| CD101 | CD101 molecule |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CHPF | chondroitin polymerizing factor |
| CISH | cytokine inducible SH2-containing protein |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPNE7 | copine VII |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| EFHD2 | EF-hand domain family, member D2 |
| ELMO3 | engulfment and cell motility 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EN1 | engrailed homeobox 1 |
| EPHA7 | EPH receptor A7 |
| EXOC5 | exocyst complex component 5 |
| FAM110B | family with sequence similarity 110, member B |
| FZD10 | frizzled class receptor 10 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GMIP | GEM interacting protein |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR39 | G protein-coupled receptor 39 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| H1F0 | H1 histone family, member 0 |
| HDAC7 | histone deacetylase 7 |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HOXB2 | homeobox B2 |
| HOXC11 | homeobox C11 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| IPO8 | importin 8 |
| ITK | IL2-inducible T-cell kinase |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LINS | lines homolog (Drosophila) |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MATN3 | matrilin 3 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OSMR | oncostatin M receptor |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLSCR2 | phospholipid scramblase 2 |
| PRSS53 | protease, serine, 53 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNF19B | ring finger protein 19B |
| RNF39 | ring finger protein 39 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIRAL2 | SIR2 antiphage like 2 |
| SIRT6 | sirtuin 6 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SSBP3 | single stranded DNA binding protein 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STRN4 | striatin, calmodulin binding protein 4 |
| SYNC | syncoilin, intermediate filament protein |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBKBP1 | TBK1 binding protein 1 |
| TIGD6 | tigger transposable element derived 6 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TTN | titin |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| WT1-AS | WT1 antisense RNA |
| YOD1 | YOD1 deubiquitinase |
| ZNF141 | zinc finger protein 141 |
| ZNF354A | zinc finger protein 354A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
| ZNF480 | zinc finger protein 480 |
| ZNF492 | zinc finger protein 492 |
