| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the proguanil-2944 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ADCY9 | adenylate cyclase 9 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APC | adenomatous polyposis coli |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATG3 | autophagy related 3 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BCR | breakpoint cluster region |
| BLVRB | biliverdin reductase B |
| C16ORF58 | chromosome 16 open reading frame 58 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CAT | catalase |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD84 | CD84 molecule |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 |
| COG5 | component of oligomeric golgi complex 5 |
| CTIF | CBP80/20-dependent translation initiation factor |
| DCTN1 | dynactin 1 |
| DHX30 | DEAH (Asp-Glu-Ala-His) box helicase 30 |
| DVL1 | dishevelled segment polarity protein 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EPHB3 | EPH receptor B3 |
| FAM50B | family with sequence similarity 50, member B |
| FAS | Fas cell surface death receptor |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FCMR | Fc fragment of IgM receptor |
| FMO5 | flavin containing monooxygenase 5 |
| FOXO4 | forkhead box O4 |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HDAC7 | histone deacetylase 7 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HTRA2 | HtrA serine peptidase 2 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGFLR1 | IGF-like family receptor 1 |
| IL6ST | interleukin 6 signal transducer |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KIF2A | kinesin heavy chain member 2A |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTB4R | leukotriene B4 receptor |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MR1 | major histocompatibility complex, class I-related |
| MT1HL1 | metallothionein 1H-like 1 |
| MTMR2 | myotubularin related protein 2 |
| MUC1 | mucin 1, cell surface associated |
| NIPBL | Nipped-B homolog (Drosophila) |
| NLRP3 | NLR family, pyrin domain containing 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PADI2 | peptidyl arginine deiminase, type II |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLAU | plasminogen activator, urokinase |
| PMCH | pro-melanin-concentrating hormone |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RPL10L | ribosomal protein L10-like |
| RPS2 | ribosomal protein S2 |
| RWDD3 | RWD domain containing 3 |
| RXRB | retinoid X receptor, beta |
| SIK3 | SIK family kinase 3 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMAD3 | SMAD family member 3 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| TCF4 | transcription factor 4 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| THBS3 | thrombospondin 3 |
| THTPA | thiamine triphosphatase |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM254 | transmembrane protein 254 |
| TRPS1 | trichorhinophalangeal syndrome I |
| UCN | urocortin |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZNF428 | zinc finger protein 428 |
| ZNF639 | zinc finger protein 639 |
| ZNF695 | zinc finger protein 695 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACPP | acid phosphatase, prostate |
| AEN | apoptosis enhancing nuclease |
| ALOX12 | arachidonate 12-lipoxygenase |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BTNL3 | butyrophilin-like 3 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CCDC176 | coiled-coil domain containing 176 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDK3 | cyclin-dependent kinase 3 |
| CES3 | carboxylesterase 3 |
| CFP | complement factor properdin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL9A2 | collagen, type IX, alpha 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CST3 | cystatin C |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CUX2 | cut-like homeobox 2 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP8 | dual specificity phosphatase 8 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EHD3 | EH-domain containing 3 |
| FAM188A | family with sequence similarity 188, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FDXR | ferredoxin reductase |
| FGL2 | fibrinogen-like 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR22 | G protein-coupled receptor 22 |
| GRAMD1B | GRAM domain containing 1B |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA1 | homeobox A1 |
| HP | haptoglobin |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICK | intestinal cell (MAK-like) kinase |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ITGB7 | integrin, beta 7 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| JADE3 | jade family PHD finger 3 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLK5 | kallikrein-related peptidase 5 |
| LIMD2 | LIM domain containing 2 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC20 | leucine rich repeat containing 20 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MREG | melanoregulin |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYO19 | myosin XIX |
| NBEA | neurobeachin |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLA2G15 | phospholipase A2, group XV |
| PLSCR4 | phospholipid scramblase 4 |
| PNOC | prepronociceptin |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| REEP4 | receptor accessory protein 4 |
| RETN | resistin |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SHPK | sedoheptulokinase |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SSBP3 | single stranded DNA binding protein 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRAF1 | TNF receptor-associated factor 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF552 | zinc finger protein 552 |
| ZNF574 | zinc finger protein 574 |
| ZNF701 | zinc finger protein 701 |
