| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the proguanil-5506 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| AOX1 | aldehyde oxidase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOE | apolipoprotein E |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ATG13 | autophagy related 13 |
| ATRN | attractin |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD101 | CD101 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK3 | cyclin-dependent kinase 3 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| ELN | elastin |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EVPL | envoplakin |
| GMPR | guanosine monophosphate reductase |
| GPR21 | G protein-coupled receptor 21 |
| HIST1H1E | histone cluster 1, H1e |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IFNA17 | interferon, alpha 17 |
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT17 | keratin 17, type I |
| LAMB3 | laminin, beta 3 |
| LAT2 | linker for activation of T cells family, member 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LONP2 | lon peptidase 2, peroxisomal |
| LRRN3 | leucine rich repeat neuronal 3 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MED25 | mediator complex subunit 25 |
| MEF2D | myocyte enhancer factor 2D |
| MX2 | MX dynamin-like GTPase 2 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NF1 | neurofibromin 1 |
| PEG10 | paternally expressed 10 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMEL | premelanosome protein |
| POU5F1B | POU class 5 homeobox 1B |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| QSER1 | glutamine and serine rich 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RPS9 | ribosomal protein S9 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SCG2 | secretogranin II |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SIRT4 | sirtuin 4 |
| SLA | Src-like-adaptor |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC35G2 | solute carrier family 35, member G2 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| STRN3 | striatin, calmodulin binding protein 3 |
| STX7 | syntaxin 7 |
| SYCP1 | synaptonemal complex protein 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| ULBP1 | UL16 binding protein 1 |
| ULBP2 | UL16 binding protein 2 |
| WIZ | widely interspaced zinc finger motifs |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF197 | zinc finger protein 197 |
| ZNF304 | zinc finger protein 304 |
| ZNF639 | zinc finger protein 639 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC6 | armadillo repeat containing 6 |
| AXIN1 | axin 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD83 | CD83 molecule |
| CDC45 | cell division cycle 45 |
| CHKB | choline kinase beta |
| CHPF | chondroitin polymerizing factor |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| COMMD10 | COMM domain containing 10 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EMD | emerin |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM110B | family with sequence similarity 110, member B |
| FBXO22 | F-box protein 22 |
| FHOD1 | formin homology 2 domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXD11 | homeobox D11 |
| HPSE | heparanase |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGFLR1 | IGF-like family receptor 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF6 | interferon regulatory factor 6 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| JUNB | jun B proto-oncogene |
| KAT2A | K(lysine) acetyltransferase 2A |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAMB2 | laminin, beta 2 (laminin S) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC20 | leucine rich repeat containing 20 |
| MAMLD1 | mastermind-like domain containing 1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAP9 | microtubule-associated protein 9 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MKS1 | Meckel syndrome, type 1 |
| NES | nestin |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NLRX1 | NLR family member X1 |
| ONECUT2 | one cut homeobox 2 |
| OTUD3 | OTU deubiquitinase 3 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PISD | phosphatidylserine decarboxylase |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RANGRF | RAN guanine nucleotide release factor |
| RASA2 | RAS p21 protein activator 2 |
| RGS19 | regulator of G-protein signaling 19 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SH2B3 | SH2B adaptor protein 3 |
| SIK1 | salt-inducible kinase 1 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMIM14 | small integral membrane protein 14 |
| TMEM242 | transmembrane protein 242 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TUBA3C | tubulin, alpha 3c |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF573 | zinc finger protein 573 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
