prolonged Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

378 genes co-occuring with the biological term prolonged in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRA1B adrenoceptor alpha 1B
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGRN agrin
AGRP agouti related neuropeptide
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOA1 apolipoprotein A-I
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARG2 arginase 2
ARHGAP1 Rho GTPase activating protein 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB2 arrestin, beta 2
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATR ATR serine/threonine kinase
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BGLAP bone gamma-carboxyglutamate (gla) protein
BIK BCL2-interacting killer (apoptosis-inducing)
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BTG2 BTG family, member 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
C5 complement component 5
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CALCR calcitonin receptor
CAMP cathelicidin antimicrobial peptide
CAPN10 calpain 10
CAPNS2 calpain, small subunit 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL21 chemokine (C-C motif) ligand 21
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD209 CD209 molecule
CD276 CD276 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDA cytidine deaminase
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CHAT choline O-acetyltransferase
CHEK1 checkpoint kinase 1
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLOCK clock circadian regulator
CMA1 chymase 1, mast cell
COMT catechol-O-methyltransferase
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNS cystinosin, lysosomal cystine transporter
CUL4B cullin 4B
CXADR coxsackie virus and adenovirus receptor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYR61 cysteine-rich, angiogenic inducer, 61
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DMPK dystrophia myotonica-protein kinase
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DPYD dihydropyrimidine dehydrogenase
DRD2 dopamine receptor D2
DUSP9 dual specificity phosphatase 9
EDN1 endothelin 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EMP1 epithelial membrane protein 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXO1 exonuclease 1
EXOSC3 exosome component 3
F12 coagulation factor XII (Hageman factor)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FADD Fas (TNFRSF6)-associated via death domain
FANCD2 Fanconi anemia, complementation group D2
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGF8 fibroblast growth factor 8 (androgen-induced)
FKBP5 FK506 binding protein 5
FNDC5 fibronectin type III domain containing 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FSHB follicle stimulating hormone, beta polypeptide
G6PD glucose-6-phosphate dehydrogenase
GAS6 growth arrest-specific 6
GCG glucagon
GFI1 growth factor independent 1 transcription repressor
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GLI1 GLI family zinc finger 1
GLP1R glucagon-like peptide 1 receptor
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNRHR gonadotropin-releasing hormone receptor
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
GYG1 glycogenin 1
HAX1 HCLS1 associated protein X-1
HBEGF heparin-binding EGF-like growth factor
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HMGB1 high mobility group box 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HRAS Harvey rat sarcoma viral oncogene homolog
HRH2 histamine receptor H2
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA9 heat shock 70kDa protein 9 (mortalin)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTT huntingtin
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDO1 indoleamine 2,3-dioxygenase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL32 interleukin 32
IL4 interleukin 4
IL6 interleukin 6
INS insulin
IRAK1 interleukin-1 receptor-associated kinase 1
IRF4 interferon regulatory factor 4
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEP leptin
LEPQTL1 Leptin, serum levels of
LEPR leptin receptor
LIN28B lin-28 homolog B (C. elegans)
LIPC lipase, hepatic
LMNA lamin A/C
LTA lymphotoxin alpha
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MERTK MER proto-oncogene, tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MICU1 mitochondrial calcium uptake 1
MIR133A1 microRNA 133a-1
MIR134 microRNA 134
MIR146A microRNA 146a
MIR155 microRNA 155
MIR17 microRNA 17
MIR192 microRNA 192
MIR486-1 microRNA 486-1
MLANA melan-A
MLH1 mutL homolog 1
MMP9 matrix metallopeptidase 9
MNS1 meiosis-specific nuclear structural 1
MSLN mesothelin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-1 NK2 homeobox 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NOX1 NADPH oxidase 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NQO1 NAD(P)H dehydrogenase, quinone 1
NRP2 neuropilin 2
OTUD6B OTU domain containing 6B
OXT oxytocin/neurophysin I prepropeptide
PADI2 peptidyl arginine deiminase, type II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP1 poly (ADP-ribose) polymerase 1
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER1 period circadian clock 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAT plasminogen activator, tissue
PLG plasminogen
PLIN2 perilipin 2
PNOC prepronociceptin
PPL periplakin
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP5C protein phosphatase 5, catalytic subunit
PRF1 perforin 1 (pore forming protein)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCZ protein kinase C, zeta
PRL prolactin
PTEN phosphatase and tensin homolog
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTPRE protein tyrosine phosphatase, receptor type, E
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP9 RAN binding protein 9
RBM3 RNA binding motif (RNP1, RRM) protein 3
RDH8 retinol dehydrogenase 8 (all-trans)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RHOA ras homolog family member A
RLN2 relaxin 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS14 ribosomal protein S14
RRM1 ribonucleotide reductase M1
RXFP1 relaxin/insulin-like family peptide receptor 1
RXFP2 relaxin/insulin-like family peptide receptor 2
S100A12 S100 calcium binding protein A12
SCEL sciellin
SCN1A sodium channel, voltage gated, type I alpha subunit
SDC1 syndecan 1
SDC3 syndecan 3
SELPLG selectin P ligand
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOCS1 suppressor of cytokine signaling 1
SOD1 superoxide dismutase 1, soluble
SOX11 SRY (sex determining region Y)-box 11
SPDEF SAM pointed domain containing ETS transcription factor
SPRR1B small proline-rich protein 1B
SPRR3 small proline-rich protein 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTB spectrin, beta, erythrocytic
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TERT telomerase reverse transcriptase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TP73 tumor protein p73
TRAF2 TNF receptor-associated factor 2
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TTR transthyretin
TXN thioredoxin
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
TXNIP thioredoxin interacting protein
UBB ubiquitin B
UBC ubiquitin C
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2S ubiquitin-conjugating enzyme E2S
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
USP15 ubiquitin specific peptidase 15
VASP vasodilator-stimulated phosphoprotein
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VWF von Willebrand factor
WISP1 WNT1 inducible signaling pathway protein 1
WRN Werner syndrome, RecQ helicase-like
XAGE1B X antigen family, member 1B
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YBX1 Y box binding protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFP36 ZFP36 ring finger protein