promazine-2173 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the promazine-2173 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIF1 allograft inflammatory factor 1
ALPI alkaline phosphatase, intestinal
ASMT acetylserotonin O-methyltransferase
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL2L1 BCL2-like 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD177 CD177 molecule
CHM choroideremia (Rab escort protein 1)
CLMN calmin (calponin-like, transmembrane)
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
CTSV cathepsin V
DEFA4 defensin, alpha 4, corticostatin
DHRS7 dehydrogenase/reductase (SDR family) member 7
DPY19L1P1 DPY19L1 pseudogene 1
DTX2 deltex 2, E3 ubiquitin ligase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDRF1 erythroid differentiation regulatory factor 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERC2-IT1 ERC2 intronic transcript 1
FAM120C family with sequence similarity 120C
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FERMT1 fermitin family member 1
FGF23 fibroblast growth factor 23
FKBP8 FK506 binding protein 8, 38kDa
FLT1 fms-related tyrosine kinase 1
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPC1 glypican 1
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
HFE hemochromatosis
HIST1H2BN histone cluster 1, H2bn
HIST1H3G histone cluster 1, H3g
HNF1B HNF1 homeobox B
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
INHBA inhibin, beta A
IQSEC2 IQ motif and Sec7 domain 2
KLC2 kinesin light chain 2
KRT31 keratin 31, type I
LAMP1 lysosomal-associated membrane protein 1
LIMD2 LIM domain containing 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP4 microtubule-associated protein 4
MAPK11 mitogen-activated protein kinase 11
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MARC1 mitochondrial amidoxime reducing component 1
MET MET proto-oncogene, receptor tyrosine kinase
MFAP5 microfibrillar associated protein 5
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MSR1 macrophage scavenger receptor 1
MXD4 MAX dimerization protein 4
MYO9B myosin IXB
NES nestin
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NLRP1 NLR family, pyrin domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOX1 NADPH oxidase 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OXCT2 3-oxoacid CoA transferase 2
PCDHGA8 protocadherin gamma subfamily A, 8
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDPN podoplanin
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POU2F2 POU class 2 homeobox 2
PRDM1 PR domain containing 1, with ZNF domain
PRELP proline/arginine-rich end leucine-rich repeat protein
PRLH prolactin releasing hormone
RAB6A RAB6A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM17 RNA binding motif protein 17
RBM5 RNA binding motif protein 5
REPS2 RALBP1 associated Eps domain containing 2
RHEB Ras homolog enriched in brain
RIBC2 RIB43A domain with coiled-coils 2
RNF25 ring finger protein 25
RNF39 ring finger protein 39
RPL23AP53 ribosomal protein L23a pseudogene 53
SCGN secretagogin, EF-hand calcium binding protein
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMAD3 SMAD family member 3
SMPX small muscle protein, X-linked
SOX13 SRY (sex determining region Y)-box 13
SOX2 SRY (sex determining region Y)-box 2
STK11 serine/threonine kinase 11
SYCE1L synaptonemal complex central element protein 1-like
TAC3 tachykinin 3
TAS2R1 taste receptor, type 2, member 1
THY1 Thy-1 cell surface antigen
TMPRSS5 transmembrane protease, serine 5
TRD T cell receptor delta locus
USP22 ubiquitin specific peptidase 22
WDR4 WD repeat domain 4

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACOX2 acyl-CoA oxidase 2, branched chain
ALPK1 alpha-kinase 1
AOAH acyloxyacyl hydrolase (neutrophil)
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BHLHE41 basic helix-loop-helix family, member e41
BPI bactericidal/permeability-increasing protein
CCDC88C coiled-coil domain containing 88C
CD320 CD320 molecule
CDA cytidine deaminase
CDK3 cyclin-dependent kinase 3
CLDND1 claudin domain containing 1
CPNE1 copine I
CRELD2 cysteine-rich with EGF-like domains 2
CTRL chymotrypsin-like
CUL9 cullin 9
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DDN dendrin
DFNA5 deafness, autosomal dominant 5
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAL4 dynein, axonemal, light chain 4
EFNA3 ephrin-A3
ELP6 elongator acetyltransferase complex subunit 6
ENO2 enolase 2 (gamma, neuronal)
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
EXOSC1 exosome component 1
FAM188A family with sequence similarity 188, member A
FGL1 fibrinogen-like 1
FJX1 four jointed box 1 (Drosophila)
FSTL3 follistatin-like 3 (secreted glycoprotein)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GGTLC1 gamma-glutamyltransferase light chain 1
GPR19 G protein-coupled receptor 19
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HPSE heparanase
IFITM3 interferon induced transmembrane protein 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INA internexin neuronal intermediate filament protein, alpha
JADE3 jade family PHD finger 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF20A kinesin family member 20A
LY6E lymphocyte antigen 6 complex, locus E
MAGEB2 melanoma antigen family B2
MAP6D1 MAP6 domain containing 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MVD mevalonate (diphospho) decarboxylase
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEA neurobeachin
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI2 peptidyl arginine deiminase, type II
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PNOC prepronociceptin
POLL polymerase (DNA directed), lambda
PORCN porcupine homolog (Drosophila)
PROCR protein C receptor, endothelial
RAB3A RAB3A, member RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL10L ribosomal protein L10-like
RPL13P5 ribosomal protein L13 pseudogene 5
SAP30L SAP30-like
SCAMP5 secretory carrier membrane protein 5
SDCCAG3 serologically defined colon cancer antigen 3
SENP7 SUMO1/sentrin specific peptidase 7
SGCE sarcoglycan, epsilon
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNIP1 Smad nuclear interacting protein 1
SP1 Sp1 transcription factor
STX5 syntaxin 5
TCP11L1 t-complex 11, testis-specific-like 1
THEM6 thioesterase superfamily member 6
TMEM53 transmembrane protein 53
TPK1 thiamin pyrophosphokinase 1
TPM3 tropomyosin 3
TRAF1 TNF receptor-associated factor 1
TSPYL2 TSPY-like 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP20 ubiquitin specific peptidase 20
WDR62 WD repeat domain 62
ZBTB48 zinc finger and BTB domain containing 48
ZNF222 zinc finger protein 222
ZNF254 zinc finger protein 254
ZNF675 zinc finger protein 675
ZNF862 zinc finger protein 862