promazine-3752 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the promazine-3752 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADAM12 ADAM metallopeptidase domain 12
ADAM8 ADAM metallopeptidase domain 8
ADRBK1 adrenergic, beta, receptor kinase 1
ANGPT1 angiopoietin 1
ANKH ANKH inorganic pyrophosphate transport regulator
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATN1 atrophin 1
BBC3 BCL2 binding component 3
BCAP29 B-cell receptor-associated protein 29
BLZF1 basic leucine zipper nuclear factor 1
C10ORF10 chromosome 10 open reading frame 10
C11ORF16 chromosome 11 open reading frame 16
C1ORF95 chromosome 1 open reading frame 95
C2 complement component 2
CA5B carbonic anhydrase VB, mitochondrial
CCDC121 coiled-coil domain containing 121
CCL22 chemokine (C-C motif) ligand 22
CCNG2 cyclin G2
CDK13 cyclin-dependent kinase 13
CFAP70 cilia and flagella associated protein 70
CLDN1 claudin 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CRISP1 cysteine-rich secretory protein 1
DLG4 discs, large homolog 4 (Drosophila)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EFNA3 ephrin-A3
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF18 fibroblast growth factor 18
FHIT fragile histidine triad
FOSL2 FOS-like antigen 2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GPATCH4 G patch domain containing 4
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ICOS inducible T-cell co-stimulator
IFFO1 intermediate filament family orphan 1
IFT27 intraflagellar transport 27
INHBE inhibin, beta E
ITPK1 inositol-tetrakisphosphate 1-kinase
KAT8 K(lysine) acetyltransferase 8
KIAA1109 KIAA1109
KLHL25 kelch-like family member 25
LOC284244 uncharacterized LOC284244
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCTP1 multiple C2 domains, transmembrane 1
MEF2D myocyte enhancer factor 2D
MME membrane metallo-endopeptidase
MXD4 MAX dimerization protein 4
MYB v-myb avian myeloblastosis viral oncogene homolog
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRL neural retina leucine zipper
NUMA1 nuclear mitotic apparatus protein 1
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAWR PRKC, apoptosis, WT1, regulator
PCDH9 protocadherin 9
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDLIM5 PDZ and LIM domain 5
PER2 period circadian clock 2
PF4 platelet factor 4
PIGR polymeric immunoglobulin receptor
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCL2 phospholipase C-like 2
PLK3 polo-like kinase 3
PLK4 polo-like kinase 4
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RND1 Rho family GTPase 1
RNGTT RNA guanylyltransferase and 5'-phosphatase
SCN1B sodium channel, voltage gated, type I beta subunit
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SP1 Sp1 transcription factor
SULT4A1 sulfotransferase family 4A, member 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYNGR3 synaptogyrin 3
TESK1 testis-specific kinase 1
TFR2 transferrin receptor 2
TGFB2 transforming growth factor, beta 2
TMOD1 tropomodulin 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TP63 tumor protein p63
TSGA10 testis specific, 10
UBXN1 UBX domain protein 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR33 WD repeat domain 33
WSB1 WD repeat and SOCS box containing 1
YBX2 Y box binding protein 2

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAT1 adenosine deaminase, tRNA-specific 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARRB2 arrestin, beta 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BMP4 bone morphogenetic protein 4
BTF3P12 basic transcription factor 3 pseudogene 12
C22ORF46 chromosome 22 open reading frame 46
C5 complement component 5
CA9 carbonic anhydrase IX
CCDC106 coiled-coil domain containing 106
CDH7 cadherin 7, type 2
CDK20 cyclin-dependent kinase 20
CFAP69 cilia and flagella associated protein 69
CIDEC cell death-inducing DFFA-like effector c
CORO2B coronin, actin binding protein, 2B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTC1 CTS telomere maintenance complex component 1
CUL9 cullin 9
CYBRD1 cytochrome b reductase 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DOCK1 dedicator of cytokinesis 1
DTX2 deltex 2, E3 ubiquitin ligase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EXD3 exonuclease 3'-5' domain containing 3
FAM120C family with sequence similarity 120C
FBXL15 F-box and leucine-rich repeat protein 15
FBXO31 F-box protein 31
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF1 fibroblast growth factor 1 (acidic)
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
GIF gastric intrinsic factor (vitamin B synthesis)
GLDC glycine dehydrogenase (decarboxylating)
GPR19 G protein-coupled receptor 19
GTPBP2 GTP binding protein 2
HIST1H2AB histone cluster 1, H2ab
HIST1H2BM histone cluster 1, H2bm
HIST1H3G histone cluster 1, H3g
HIST1H4E histone cluster 1, H4e
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA1L heat shock 70kDa protein 1-like
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
KDM4D lysine (K)-specific demethylase 4D
KRI1 KRI1 homolog (S. cerevisiae)
LIG3 ligase III, DNA, ATP-dependent
MGC12488
MXRA8 matrix-remodelling associated 8
NAT10 N-acetyltransferase 10 (GCN5-related)
NGF nerve growth factor (beta polypeptide)
NPFFR1 neuropeptide FF receptor 1
NTSR1 neurotensin receptor 1 (high affinity)
ODF2 outer dense fiber of sperm tails 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAN2 PAN2 poly(A) specific ribonuclease subunit
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCE protein kinase C, epsilon
PRSS53 protease, serine, 53
QPCTL glutaminyl-peptide cyclotransferase-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RECQL4 RecQ protein-like 4
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNMTL1 RNA methyltransferase like 1
RPH3AL rabphilin 3A-like (without C2 domains)
SAYSD1 SAYSVFN motif domain containing 1
SCAMP5 secretory carrier membrane protein 5
SCARA3 scavenger receptor class A, member 3
SIRAL2 SIR2 antiphage like 2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC46A3 solute carrier family 46, member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX1A syntaxin 1A (brain)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIGD6 tigger transposable element derived 6
TMC5 transmembrane channel-like 5
TMEM242 transmembrane protein 242
TNS2 tensin 2
TPCN1 two pore segment channel 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D4 TSC22 domain family, member 4
TSPAN32 tetraspanin 32
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
ZNF140 zinc finger protein 140
ZNF205 zinc finger protein 205
ZNF480 zinc finger protein 480
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862
ZW10 zw10 kinetochore protein