promazine-3927 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the promazine-3927 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADGRA2 adhesion G protein-coupled receptor A2
AQP6 aquaporin 6, kidney specific
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARTN artemin
ATP10A ATPase, class V, type 10A
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BMP2 bone morphogenetic protein 2
BTN3A1 butyrophilin, subfamily 3, member A1
C19ORF66 chromosome 19 open reading frame 66
C7ORF69 chromosome 7 open reading frame 69
C9ORF16 chromosome 9 open reading frame 16
CA9 carbonic anhydrase IX
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CADM3 cell adhesion molecule 3
CCL19 chemokine (C-C motif) ligand 19
CD5 CD5 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD93 CD93 molecule
CDA cytidine deaminase
CEMIP cell migration inducing protein, hyaluronan binding
CLTA clathrin, light chain A
COL6A1 collagen, type VI, alpha 1
CRHBP corticotropin releasing hormone binding protein
CRISP2 cysteine-rich secretory protein 2
DENND1C DENN/MADD domain containing 1C
DISC1 disrupted in schizophrenia 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DVL2 dishevelled segment polarity protein 2
FCMR Fc fragment of IgM receptor
FGFR1 fibroblast growth factor receptor 1
GFI1 growth factor independent 1 transcription repressor
GGT1 gamma-glutamyltransferase 1
GPATCH4 G patch domain containing 4
GPR183 G protein-coupled receptor 183
GPSM3 G-protein signaling modulator 3
GSTA1 glutathione S-transferase alpha 1
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IGKC immunoglobulin kappa constant
IL36G interleukin 36, gamma
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA1462 KIAA1462
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLK8 kallikrein-related peptidase 8
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIME1 Lck interacting transmembrane adaptor 1
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MARK4 MAP/microtubule affinity-regulating kinase 4
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NYNRIN NYN domain and retroviral integrase containing
OPRL1 opiate receptor-like 1
PAX2 paired box 2
PDZK1IP1 PDZK1 interacting protein 1
PKNOX1 PBX/knotted 1 homeobox 1
PNPLA3 patatin-like phospholipase domain containing 3
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRM2 protamine 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RGS11 regulator of G-protein signaling 11
RHAG Rh-associated glycoprotein
RIMS3 regulating synaptic membrane exocytosis 3
RORC RAR-related orphan receptor C
RUNX1 runt-related transcription factor 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SH3BP2 SH3-domain binding protein 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPON1 spondin 1, extracellular matrix protein
SRRT serrate, RNA effector molecule
SSTR5 somatostatin receptor 5
SSX3 synovial sarcoma, X breakpoint 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUGP1 SURP and G patch domain containing 1
TRAPPC9 trafficking protein particle complex 9
TREX1 three prime repair exonuclease 1
TRIM31 tripartite motif containing 31
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
ZNF280A zinc finger protein 280A
ZNF384 zinc finger protein 384
ZNF440 zinc finger protein 440
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BMP4 bone morphogenetic protein 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
CALML5 calmodulin-like 5
CBX8 chromobox homolog 8
CCNK cyclin K
CD82 CD82 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFHR4 complement factor H-related 4
COPZ2 coatomer protein complex, subunit zeta 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L1P1 DPY19L1 pseudogene 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERN1 endoplasmic reticulum to nucleus signaling 1
FAAH fatty acid amide hydrolase
FAM155A family with sequence similarity 155, member A
FAM188A family with sequence similarity 188, member A
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FBXO22 F-box protein 22
FBXO31 F-box protein 31
FFAR2 free fatty acid receptor 2
GATA4 GATA binding protein 4
GLCE glucuronic acid epimerase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR143 G protein-coupled receptor 143
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H3F histone cluster 1, H3f
HIST1H4F histone cluster 1, H4f
HOXC5 homeobox C5
HOXC8 homeobox C8
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFT140 intraflagellar transport 140
INO80D INO80 complex subunit D
IRAK4 interleukin-1 receptor-associated kinase 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KIF13A kinesin family member 13A
KRT83 keratin 83, type II
LOC730101 uncharacterized LOC730101
LYRM9 LYR motif containing 9
MAGEB2 melanoma antigen family B2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MRPL44 mitochondrial ribosomal protein L44
MTA2 metastasis associated 1 family, member 2
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NPIPB3 nuclear pore complex interacting protein family, member B3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PCDHA6 protocadherin alpha 6
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAC1 placenta-specific 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB30 RAB30, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB40AL RAB40A, member RAS oncogene family-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFXAP regulatory factor X-associated protein
RIBC2 RIB43A domain with coiled-coils 2
RNF39 ring finger protein 39
ROM1 retinal outer segment membrane protein 1
RPA4 replication protein A4, 30kDa
RUNDC3B RUN domain containing 3B
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SPAG4 sperm associated antigen 4
ST5 suppression of tumorigenicity 5
STK16 serine/threonine kinase 16
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYCP2 synaptonemal complex protein 2
SYNC syncoilin, intermediate filament protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMLHE trimethyllysine hydroxylase, epsilon
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF682 zinc finger protein 682