| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the promethazine-5317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANKRD12 | ankyrin repeat domain 12 |
| ASPH | aspartate beta-hydroxylase |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATM | ATM serine/threonine kinase |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL9 | B-cell CLL/lymphoma 9 |
| BMP1 | bone morphogenetic protein 1 |
| C19ORF60 | chromosome 19 open reading frame 60 |
| CABIN1 | calcineurin binding protein 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CENPO | centromere protein O |
| CEP164 | centrosomal protein 164kDa |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EFNA3 | ephrin-A3 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| FAM131A | family with sequence similarity 131, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLCN | folliculin |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GALC | galactosylceramidase |
| GCAT | glycine C-acetyltransferase |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMOX1 | heme oxygenase 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL17RA | interleukin 17 receptor A |
| INSIG1 | insulin induced gene 1 |
| JRK | Jrk homolog (mouse) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KIF1A | kinesin family member 1A |
| KRT17 | keratin 17, type I |
| LAMC2 | laminin, gamma 2 |
| LAMC3 | laminin, gamma 3 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC644450 | uncharacterized LOC644450 |
| LRRC20 | leucine rich repeat containing 20 |
| LRRC49 | leucine rich repeat containing 49 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPT | microtubule-associated protein tau |
| MCOLN1 | mucolipin 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MT1F | metallothionein 1F |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD3 | MAX dimerization protein 3 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OGFR | opioid growth factor receptor |
| OSBPL2 | oxysterol binding protein-like 2 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCG1 | phospholipase C, gamma 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| RBPMS | RNA binding protein with multiple splicing |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUNX1 | runt-related transcription factor 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| TREX1 | three prime repair exonuclease 1 |
| USP22 | ubiquitin specific peptidase 22 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZNF34 | zinc finger protein 34 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AEN | apoptosis enhancing nuclease |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ANKRD36 | ankyrin repeat domain 36 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| ATG2A | autophagy related 2A |
| ATG4A | autophagy related 4A, cysteine peptidase |
| AXIN1 | axin 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| CBX7 | chromobox homolog 7 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CTSC | cathepsin C |
| CTSK | cathepsin K |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EXOC5 | exocyst complex component 5 |
| FANCF | Fanconi anemia, complementation group F |
| FEM1C | fem-1 homolog c (C. elegans) |
| FGGY | FGGY carbohydrate kinase domain containing |
| FKTN | fukutin |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GAR1 | GAR1 ribonucleoprotein |
| GBAS | glioblastoma amplified sequence |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GLCE | glucuronic acid epimerase |
| GLI3 | GLI family zinc finger 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 |
| HIRA | histone cell cycle regulator |
| HIRIP3 | HIRA interacting protein 3 |
| HIST1H1D | histone cluster 1, H1d |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| KIF16B | kinesin family member 16B |
| KRBOX4 | KRAB box domain containing 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINS | lines homolog (Drosophila) |
| LMNB1 | lamin B1 |
| MED24 | mediator complex subunit 24 |
| MEN1 | multiple endocrine neoplasia I |
| MIR22HG | MIR22 host gene |
| MNS1 | meiosis-specific nuclear structural 1 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NARFL | nuclear prelamin A recognition factor-like |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PRMT7 | protein arginine methyltransferase 7 |
| PTK6 | protein tyrosine kinase 6 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM41 | RNA binding motif protein 41 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RGS17 | regulator of G-protein signaling 17 |
| RNF113A | ring finger protein 113A |
| RPL39L | ribosomal protein L39-like |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SUSD4 | sushi domain containing 4 |
| SYTL2 | synaptotagmin-like 2 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| THAP10 | THAP domain containing 10 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TPCN1 | two pore segment channel 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TULP4 | tubby like protein 4 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| TXNL4B | thioredoxin-like 4B |
| UBXN8 | UBX domain protein 8 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| USP6NL | USP6 N-terminal like |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WWC3 | WWC family member 3 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF211 | zinc finger protein 211 |
| ZNF573 | zinc finger protein 573 |
| ZNF668 | zinc finger protein 668 |
| ZNF768 | zinc finger protein 768 |
