| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the promethazine-6477 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AJAP1 | adherens junctions associated protein 1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| APOC1 | apolipoprotein C-I |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATRNL1 | attractin-like 1 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BPIFA1 | BPI fold containing family A, member 1 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CLCA2 | chloride channel accessory 2 |
| CLSTN2 | calsyntenin 2 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CPNE7 | copine VII |
| CREBBP | CREB binding protein |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DPYS | dihydropyrimidinase |
| DUSP4 | dual specificity phosphatase 4 |
| DVL3 | dishevelled segment polarity protein 3 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EXOSC2 | exosome component 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF17 | fibroblast growth factor 17 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GAS6 | growth arrest-specific 6 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| HFE | hemochromatosis |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IGHM | immunoglobulin heavy constant mu |
| ING4 | inhibitor of growth family, member 4 |
| ITGB4 | integrin, beta 4 |
| KIAA0125 | KIAA0125 |
| KRT83 | keratin 83, type II |
| KSR1 | kinase suppressor of ras 1 |
| LHX3 | LIM homeobox 3 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MARS | methionyl-tRNA synthetase |
| MAX | MYC associated factor X |
| MMP3 | matrix metallopeptidase 3 |
| MST1 | macrophage stimulating 1 |
| MTMR7 | myotubularin related protein 7 |
| MXRA8 | matrix-remodelling associated 8 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NFRKB | nuclear factor related to kappaB binding protein |
| NPR1 | natriuretic peptide receptor 1 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OLFM1 | olfactomedin 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PADI4 | peptidyl arginine deiminase, type IV |
| PARVA | parvin, alpha |
| PDLIM5 | PDZ and LIM domain 5 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| POPDC3 | popeye domain containing 3 |
| PORCN | porcupine homolog (Drosophila) |
| PRF1 | perforin 1 (pore forming protein) |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RGS12 | regulator of G-protein signaling 12 |
| RNF19B | ring finger protein 19B |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SMAD1 | SMAD family member 1 |
| SMAD3 | SMAD family member 3 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| STAT5A | signal transducer and activator of transcription 5A |
| SYNJ1 | synaptojanin 1 |
| TACR1 | tachykinin receptor 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TMEM259 | transmembrane protein 259 |
| TP63 | tumor protein p63 |
| TRIM21 | tripartite motif containing 21 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| UTRN | utrophin |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| WSCD1 | WSC domain containing 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFPL1 | zinc finger protein-like 1 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF551 | zinc finger protein 551 |
| Symbol | Name |
|---|---|
| AFAP1 | actin filament associated protein 1 |
| AKTIP | AKT interacting protein |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ASPN | asporin |
| ATAD3A | ATPase family, AAA domain containing 3A |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAGE | B melanoma antigen |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C5AR2 | complement component 5a receptor 2 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDKN2AIP | CDKN2A interacting protein |
| CEL | carboxyl ester lipase |
| CISH | cytokine inducible SH2-containing protein |
| CLDN17 | claudin 17 |
| CLDND1 | claudin domain containing 1 |
| CLSPN | claspin |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAL4 | dynein, axonemal, light chain 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPC3 | glypican 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD4 | GRAM domain containing 4 |
| HIST1H2AL | histone cluster 1, H2al |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KLF2 | Kruppel-like factor 2 |
| KRT13 | keratin 13, type I |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LOC729164 | hCG1732469 |
| LYRM9 | LYR motif containing 9 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MED31 | mediator complex subunit 31 |
| MTCL1 | microtubule crosslinking factor 1 |
| NES | nestin |
| NPY5R | neuropeptide Y receptor Y5 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA9 | protocadherin alpha 9 |
| PCDHB8 | protocadherin beta 8 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRDM14 | PR domain containing 14 |
| PROCR | protein C receptor, endothelial |
| PROL1 | proline rich, lacrimal 1 |
| PRSS50 | protease, serine, 50 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB4B | RAB4B, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF146 | ring finger protein 146 |
| RPGRIP1L | RPGRIP1-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SFRP5 | secreted frizzled-related protein 5 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SREK1IP1 | SREK1-interacting protein 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYT17 | synaptotagmin XVII |
| TCHH | trichohyalin |
| TCTN2 | tectonic family member 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM254 | transmembrane protein 254 |
| TMEM62 | transmembrane protein 62 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTBK2 | tau tubulin kinase 2 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBTD1 | ubiquitin domain containing 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR25 | WD repeat domain 25 |
| WDR7 | WD repeat domain 7 |
| WDR76 | WD repeat domain 76 |
| WDR91 | WD repeat domain 91 |
| ZNF10 | zinc finger protein 10 |
| ZNF324 | zinc finger protein 324 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF571 | zinc finger protein 571 |
| ZNF586 | zinc finger protein 586 |
| ZNF675 | zinc finger protein 675 |
| ZNF778 | zinc finger protein 778 |