promethazine-6477 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the promethazine-6477 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AGMAT agmatine ureohydrolase (agmatinase)
AJAP1 adherens junctions associated protein 1
ANG angiogenin, ribonuclease, RNase A family, 5
APOC1 apolipoprotein C-I
ARNT aryl hydrocarbon receptor nuclear translocator
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATRNL1 attractin-like 1
BEGAIN brain-enriched guanylate kinase-associated
BPIFA1 BPI fold containing family A, member 1
C9ORF156 chromosome 9 open reading frame 156
CLCA2 chloride channel accessory 2
CLSTN2 calsyntenin 2
CNOT2 CCR4-NOT transcription complex, subunit 2
COL11A1 collagen, type XI, alpha 1
COL3A1 collagen, type III, alpha 1
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
CREBBP CREB binding protein
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DEFA4 defensin, alpha 4, corticostatin
DPYS dihydropyrimidinase
DUSP4 dual specificity phosphatase 4
DVL3 dishevelled segment polarity protein 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EXOSC2 exosome component 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF17 fibroblast growth factor 17
FGFBP1 fibroblast growth factor binding protein 1
FGFR1 fibroblast growth factor receptor 1
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11710 uncharacterized protein FLJ11710
GAS6 growth arrest-specific 6
GNG13 guanine nucleotide binding protein (G protein), gamma 13
HFE hemochromatosis
HLA-J major histocompatibility complex, class I, J (pseudogene)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHM immunoglobulin heavy constant mu
ING4 inhibitor of growth family, member 4
ITGB4 integrin, beta 4
KIAA0125 KIAA0125
KRT83 keratin 83, type II
KSR1 kinase suppressor of ras 1
LHX3 LIM homeobox 3
MAP2K2 mitogen-activated protein kinase kinase 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MARS methionyl-tRNA synthetase
MAX MYC associated factor X
MMP3 matrix metallopeptidase 3
MST1 macrophage stimulating 1
MTMR7 myotubularin related protein 7
MXRA8 matrix-remodelling associated 8
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NFRKB nuclear factor related to kappaB binding protein
NPR1 natriuretic peptide receptor 1
NYNRIN NYN domain and retroviral integrase containing
OLFM1 olfactomedin 1
OPCML opioid binding protein/cell adhesion molecule-like
PADI4 peptidyl arginine deiminase, type IV
PARVA parvin, alpha
PDLIM5 PDZ and LIM domain 5
PLD1 phospholipase D1, phosphatidylcholine-specific
POPDC3 popeye domain containing 3
PORCN porcupine homolog (Drosophila)
PRF1 perforin 1 (pore forming protein)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKG2 protein kinase, cGMP-dependent, type II
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGS12 regulator of G-protein signaling 12
RNF19B ring finger protein 19B
RTEL1 regulator of telomere elongation helicase 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STAT5A signal transducer and activator of transcription 5A
SYNJ1 synaptojanin 1
TACR1 tachykinin receptor 1
TBC1D17 TBC1 domain family, member 17
TMEM259 transmembrane protein 259
TP63 tumor protein p63
TRIM21 tripartite motif containing 21
TTC38 tetratricopeptide repeat domain 38
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UTRN utrophin
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
WNT8B wingless-type MMTV integration site family, member 8B
WSCD1 WSC domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPL1 zinc finger protein-like 1
ZMAT4 zinc finger, matrin-type 4
ZNF551 zinc finger protein 551

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AKTIP AKT interacting protein
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASPN asporin
ATAD3A ATPase family, AAA domain containing 3A
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAGE B melanoma antigen
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C10ORF95 chromosome 10 open reading frame 95
C14ORF93 chromosome 14 open reading frame 93
C5AR2 complement component 5a receptor 2
C7ORF69 chromosome 7 open reading frame 69
CDH10 cadherin 10, type 2 (T2-cadherin)
CDKN2AIP CDKN2A interacting protein
CEL carboxyl ester lipase
CISH cytokine inducible SH2-containing protein
CLDN17 claudin 17
CLDND1 claudin domain containing 1
CLSPN claspin
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF13 DDB1 and CUL4 associated factor 13
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
GLS2 glutaminase 2 (liver, mitochondrial)
GPC3 glypican 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD4 GRAM domain containing 4
HIST1H2AL histone cluster 1, H2al
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IGSF1 immunoglobulin superfamily, member 1
IL12RB1 interleukin 12 receptor, beta 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLF2 Kruppel-like factor 2
KRT13 keratin 13, type I
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LOC729164 hCG1732469
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MED31 mediator complex subunit 31
MTCL1 microtubule crosslinking factor 1
NES nestin
NPY5R neuropeptide Y receptor Y5
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHA9 protocadherin alpha 9
PCDHB8 protocadherin beta 8
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRDM14 PR domain containing 14
PROCR protein C receptor, endothelial
PROL1 proline rich, lacrimal 1
PRSS50 protease, serine, 50
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB4B RAB4B, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF146 ring finger protein 146
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
SCGB2A2 secretoglobin, family 2A, member 2
SFRP5 secreted frizzled-related protein 5
SIGLEC15 sialic acid binding Ig-like lectin 15
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A8 solute carrier family 12, member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SREK1IP1 SREK1-interacting protein 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT17 synaptotagmin XVII
TCHH trichohyalin
TCTN2 tectonic family member 2
TICAM1 toll-like receptor adaptor molecule 1
TMEM254 transmembrane protein 254
TMEM62 transmembrane protein 62
TRAPPC2 trafficking protein particle complex 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTBK2 tau tubulin kinase 2
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBTD1 ubiquitin domain containing 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEZT vezatin, adherens junctions transmembrane protein
WDR25 WD repeat domain 25
WDR7 WD repeat domain 7
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
ZNF10 zinc finger protein 10
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF571 zinc finger protein 571
ZNF586 zinc finger protein 586
ZNF675 zinc finger protein 675
ZNF778 zinc finger protein 778