| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the promethazine-6717 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AQP5 | aquaporin 5 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C2CD2L | C2CD2-like |
| CCDC57 | coiled-coil domain containing 57 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK13 | cyclin-dependent kinase 13 |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CISH | cytokine inducible SH2-containing protein |
| COL11A1 | collagen, type XI, alpha 1 |
| CST1 | cystatin SN |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTH3 | cytohesin 3 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DKKL1 | dickkopf-like 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| EDA | ectodysplasin A |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ESR1 | estrogen receptor 1 |
| EXO5 | exonuclease 5 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| GAS7 | growth arrest-specific 7 |
| GPR1 | G protein-coupled receptor 1 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HRK | harakiri, BCL2 interacting protein |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL23A | interleukin 23, alpha subunit p19 |
| IL6 | interleukin 6 |
| INSIG1 | insulin induced gene 1 |
| JPH3 | junctophilin 3 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KLK12 | kallikrein-related peptidase 12 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT7 | keratin 7, type II |
| LAMC2 | laminin, gamma 2 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MED25 | mediator complex subunit 25 |
| MEF2D | myocyte enhancer factor 2D |
| MEGF6 | multiple EGF-like-domains 6 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MTCP1 | mature T-cell proliferation 1 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| MYO1B | myosin IB |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OMG | oligodendrocyte myelin glycoprotein |
| PAX8 | paired box 8 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PROL1 | proline rich, lacrimal 1 |
| PRTN3 | proteinase 3 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RARA | retinoic acid receptor, alpha |
| RPL3L | ribosomal protein L3-like |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SFTPB | surfactant protein B |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SYT1 | synaptotagmin I |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TBX2 | T-box 2 |
| TGFB2 | transforming growth factor, beta 2 |
| TJP3 | tight junction protein 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TOX | thymocyte selection-associated high mobility group box |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VASH1 | vasohibin 1 |
| ZNF280B | zinc finger protein 280B |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| AXIN1 | axin 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C1RL | complement component 1, r subcomponent-like |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CBX8 | chromobox homolog 8 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHM | choroideremia (Rab escort protein 1) |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CTSD | cathepsin D |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DLL3 | delta-like 3 (Drosophila) |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EXOC5 | exocyst complex component 5 |
| FAM184A | family with sequence similarity 184, member A |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR87 | G protein-coupled receptor 87 |
| GRAMD1C | GRAM domain containing 1C |
| GTF2I | general transcription factor IIi |
| H2BFS | H2B histone family, member S (pseudogene) |
| HELZ | helicase with zinc finger |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IPO8 | importin 8 |
| IQCG | IQ motif containing G |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0754 | KIAA0754 |
| KNTC1 | kinetochore associated 1 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MAGEH1 | melanoma antigen family H1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MCC | mutated in colorectal cancers |
| MCM3 | minichromosome maintenance complex component 3 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MXD3 | MAX dimerization protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| ORC1 | origin recognition complex, subunit 1 |
| OSBP2 | oxysterol binding protein 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PALMD | palmdelphin |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PARPBP | PARP1 binding protein |
| PDE8B | phosphodiesterase 8B |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SPEG | SPEG complex locus |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM25 | tripartite motif containing 25 |
| TSPAN1 | tetraspanin 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| ULBP2 | UL16 binding protein 2 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR62 | WD repeat domain 62 |
| XK | X-linked Kx blood group |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YY2 | YY2 transcription factor |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF141 | zinc finger protein 141 |
| ZNF529 | zinc finger protein 529 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
