prominent Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

282 genes co-occuring with the biological term prominent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACKR2 atypical chemokine receptor 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ADAM12 ADAM metallopeptidase domain 12
ADGRE1 adhesion G protein-coupled receptor E1
ADGRE3 adhesion G protein-coupled receptor E3
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2B adenosine A2b receptor
AGER advanced glycosylation end product-specific receptor
AHSG alpha-2-HS-glycoprotein
AIP aryl hydrocarbon receptor interacting protein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALOX15 arachidonate 15-lipoxygenase
ANGPTL4 angiopoietin-like 4
ANKK1 ankyrin repeat and kinase domain containing 1
ANXA2 annexin A2
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARNT aryl hydrocarbon receptor nuclear translocator
ASCL1 achaete-scute family bHLH transcription factor 1
AURKA aurora kinase A
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL2L1 BCL2-like 1
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BMX BMX non-receptor tyrosine kinase
BPI bactericidal/permeability-increasing protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
C3 complement component 3
C5AR2 complement component 5a receptor 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CADM1 cell adhesion molecule 1
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV3 caveolin 3
CCDC78 coiled-coil domain containing 78
CCND2 cyclin D2
CCNK cyclin K
CD14 CD14 molecule
CD274 CD274 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD9 CD9 molecule
CDC14B cell division cycle 14B
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CERKL ceramide kinase-like
CHD8 chromodomain helicase DNA binding protein 8
CLEC16A C-type lectin domain family 16, member A
CNR1 cannabinoid receptor 1 (brain)
COCH cochlin
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRISP2 cysteine-rich secretory protein 2
CRISP3 cysteine-rich secretory protein 3
CRP C-reactive protein, pentraxin-related
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYSLTR1 cysteinyl leukotriene receptor 1
DAOA D-amino acid oxidase activator
DDIT3 DNA-damage-inducible transcript 3
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK2 dedicator of cytokinesis 2
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DRD2 dopamine receptor D2
DSG2 desmoglein 2
DTNBP1 dystrobrevin binding protein 1
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ENO2 enolase 2 (gamma, neuronal)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZR ezrin
FBN1 fibrillin 1
FGF18 fibroblast growth factor 18
FMO1 flavin containing monooxygenase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FPR2 formyl peptide receptor 2
FTO fat mass and obesity associated
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBP3 guanylate binding protein 3
GCGR glucagon receptor
GCK glucokinase (hexokinase 4)
GFI1 growth factor independent 1 transcription repressor
GFI1B growth factor independent 1B transcription repressor
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJB2 gap junction protein, beta 2, 26kDa
GNAS GNAS complex locus
GPR143 G protein-coupled receptor 143
GSK3B glycogen synthase kinase 3 beta
HBB hemoglobin, beta
HBEGF heparin-binding EGF-like growth factor
HDAC2 histone deacetylase 2
HDAC8 histone deacetylase 8
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HK2 hexokinase 2
HLA-A major histocompatibility complex, class I, A
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMGA2 high mobility group AT-hook 2
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HPSE heparanase
HSPG2 heparan sulfate proteoglycan 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2R insulin-like growth factor 2 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL12A interleukin 12A
IL12B interleukin 12B
IL15 interleukin 15
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
IL7 interleukin 7
ILK integrin-linked kinase
INHBB inhibin, beta B
IRF7 interferon regulatory factor 7
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KMT2A lysine (K)-specific methyltransferase 2A
LGALS1 lectin, galactoside-binding, soluble, 1
LMNA lamin A/C
LRRK2 leucine-rich repeat kinase 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCL1 myeloid cell leukemia 1
MCOLN3 mucolipin 3
MECP2 methyl CpG binding protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
MIR101-1 microRNA 101-1
MIR146A microRNA 146a
MIR154 microRNA 154
MIR21 microRNA 21
MIR221 microRNA 221
MIR31 microRNA 31
MIR451A microRNA 451a
MIRLET7G microRNA let-7g
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MLN motilin
MMP3 matrix metallopeptidase 3
MPDZ multiple PDZ domain protein
MSH2 mutS homolog 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MX1 MX dynamin-like GTPase 1
MYO1B myosin IB
MYO1E myosin IE
NAMPT nicotinamide phosphoribosyltransferase
NCAM1 neural cell adhesion molecule 1
NEUROD1 neuronal differentiation 1
NEUROG3 neurogenin 3
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP5 NLR family, pyrin domain containing 5
NODAL nodal growth differentiation factor
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NR0B1 nuclear receptor subfamily 0, group B, member 1
NT5C2 5'-nucleotidase, cytosolic II
NT5E 5'-nucleotidase, ecto (CD73)
OCA2 oculocutaneous albinism II
OPRM1 opioid receptor, mu 1
ORAI1 ORAI calcium release-activated calcium modulator 1
ORAI2 ORAI calcium release-activated calcium modulator 2
ORAI3 ORAI calcium release-activated calcium modulator 3
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PARP1 poly (ADP-ribose) polymerase 1
PAWR PRKC, apoptosis, WT1, regulator
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PF4 platelet factor 4
PGR progesterone receptor
PICK1 protein interacting with PRKCA 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
PLK1 polo-like kinase 1
PNPLA3 patatin-like phospholipase domain containing 3
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PRDM2 PR domain containing 2, with ZNF domain
PRNP prion protein
PRX periaxin
PSEN1 presenilin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PXN paxillin
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAB10 RAB10, member RAS oncogene family
RAB11A RAB11A, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RNF213 ring finger protein 213
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS15A ribosomal protein S15a
RYR1 ryanodine receptor 1 (skeletal)
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCARB1 scavenger receptor class B, member 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SFTPC surfactant protein C
SGMS2 sphingomyelin synthase 2
SLA Src-like-adaptor
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC44A2 solute carrier family 44 (choline transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLITRK1 SLIT and NTRK-like family, member 1
SLPI secretory leukocyte peptidase inhibitor
SMN1 survival of motor neuron 1, telomeric
SOX3 SRY (sex determining region Y)-box 3
SOX5 SRY (sex determining region Y)-box 5
SOX9 SRY (sex determining region Y)-box 9
SPG20 spastic paraplegia 20 (Troyer syndrome)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SSTR1 somatostatin receptor 1
STIM1 stromal interaction molecule 1
SYK spleen tyrosine kinase
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNNT2 troponin T type 2 (cardiac)
TOM1L1 target of myb1 (chicken)-like 1
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TSPY1 testis specific protein, Y-linked 1
TXN thioredoxin
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VAV1 vav 1 guanine nucleotide exchange factor
WNT4 wingless-type MMTV integration site family, member 4
ZFX zinc finger protein, X-linked