| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the pronetalol-2902 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATF7IP | activating transcription factor 7 interacting protein |
| BLNK | B-cell linker |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CA7 | carbonic anhydrase VII |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CD209 | CD209 molecule |
| CD34 | CD34 molecule |
| CLEC4A | C-type lectin domain family 4, member A |
| CNTN1 | contactin 1 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYB5A | cytochrome b5 type A (microsomal) |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| ETV1 | ets variant 1 |
| EXOSC2 | exosome component 2 |
| FCMR | Fc fragment of IgM receptor |
| FER | fer (fps/fes related) tyrosine kinase |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FLT1 | fms-related tyrosine kinase 1 |
| FN1 | fibronectin 1 |
| GAA | glucosidase, alpha; acid |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GFER | growth factor, augmenter of liver regeneration |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GP6 | glycoprotein VI (platelet) |
| GPR107 | G protein-coupled receptor 107 |
| HDLBP | high density lipoprotein binding protein |
| HOXB5 | homeobox B5 |
| HOXB6 | homeobox B6 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HYI | hydroxypyruvate isomerase (putative) |
| IDUA | iduronidase, alpha-L- |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIAA0226L | KIAA0226-like |
| KLHL3 | kelch-like family member 3 |
| LMNA | lamin A/C |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC6 | leucine rich repeat containing 6 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MYL10 | myosin, light chain 10, regulatory |
| MYO5C | myosin VC |
| NEBL | nebulette |
| NIPAL2 | NIPA-like domain containing 2 |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPR3 | natriuretic peptide receptor 3 |
| PAPPA2 | pappalysin 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDLIM4 | PDZ and LIM domain 4 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PHF1 | PHD finger protein 1 |
| PHF7 | PHD finger protein 7 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCH1 | phospholipase C, eta 1 |
| PLK3 | polo-like kinase 3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRX | periaxin |
| PTCRA | pre T-cell antigen receptor alpha |
| REC8 | REC8 meiotic recombination protein |
| RGS10 | regulator of G-protein signaling 10 |
| RNF17 | ring finger protein 17 |
| RNF39 | ring finger protein 39 |
| SAA4 | serum amyloid A4, constitutive |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SOCS2 | suppressor of cytokine signaling 2 |
| SP140 | SP140 nuclear body protein |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STOM | stomatin |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TACR1 | tachykinin receptor 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBX6 | T-box 6 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFF2 | trefoil factor 2 |
| TPMT | thiopurine S-methyltransferase |
| TRIM29 | tripartite motif containing 29 |
| TUBA3C | tubulin, alpha 3c |
| VASH1 | vasohibin 1 |
| VPRBP | Vpr (HIV-1) binding protein |
| YBX3 | Y box binding protein 3 |
| ZNF177 | zinc finger protein 177 |
| ZNF276 | zinc finger protein 276 |
| ZNF492 | zinc finger protein 492 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ABHD17B | abhydrolase domain containing 17B |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AKTIP | AKT interacting protein |
| ANO10 | anoctamin 10 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C14ORF159 | chromosome 14 open reading frame 159 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CCDC109B | coiled-coil domain containing 109B |
| CD82 | CD82 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP7 | charged multivesicular body protein 7 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) |
| DEAF1 | DEAF1 transcription factor |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNMBP | dynamin binding protein |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| E4F1 | E4F transcription factor 1 |
| ECI1 | enoyl-CoA delta isomerase 1 |
| ELAC1 | elaC ribonuclease Z 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENAH | enabled homolog (Drosophila) |
| ERCC3 | excision repair cross-complementation group 3 |
| FAM50B | family with sequence similarity 50, member B |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FPGS | folylpolyglutamate synthase |
| GCH1 | GTP cyclohydrolase 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPHN | gephyrin |
| GPR63 | G protein-coupled receptor 63 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA1 | homeobox A1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IPO8 | importin 8 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KIF18A | kinesin family member 18A |
| LOC157562 | uncharacterized LOC157562 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAPK12 | mitogen-activated protein kinase 12 |
| MCRS1 | microspherule protein 1 |
| METTL21B | methyltransferase like 21B |
| METTL8 | methyltransferase like 8 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NABP2 | nucleic acid binding protein 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PDZD7 | PDZ domain containing 7 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PLA2G15 | phospholipase A2, group XV |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PROSER1 | proline and serine rich 1 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF123 | ring finger protein 123 |
| ROGDI | rogdi homolog (Drosophila) |
| RUVBL1 | RuvB-like AAA ATPase 1 |
| SALL2 | spalt-like transcription factor 2 |
| SCAI | suppressor of cancer cell invasion |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPAG1 | sperm associated antigen 1 |
| SPRYD7 | SPRY domain containing 7 |
| SSBP3 | single stranded DNA binding protein 3 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TEC | tec protein tyrosine kinase |
| THAP10 | THAP domain containing 10 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM16 | tripartite motif containing 16 |
| TSPYL2 | TSPY-like 2 |
| TUBA3D | tubulin, alpha 3d |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR91 | WD repeat domain 91 |
| YIPF1 | Yip1 domain family, member 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF225 | zinc finger protein 225 |
| ZNF250 | zinc finger protein 250 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF480 | zinc finger protein 480 |
| ZNF529 | zinc finger protein 529 |