pronetalol-3984 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pronetalol-3984 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM23 ADAM metallopeptidase domain 23
ADARB1 adenosine deaminase, RNA-specific, B1
ADD2 adducin 2 (beta)
AKAP5 A kinase (PRKA) anchor protein 5
AKAP7 A kinase (PRKA) anchor protein 7
AKR1D1 aldo-keto reductase family 1, member D1
APOM apolipoprotein M
AQP1 aquaporin 1 (Colton blood group)
ATN1 atrophin 1
BAGE B melanoma antigen
BEAN1 brain expressed, associated with NEDD4, 1
C10ORF12 chromosome 10 open reading frame 12
C8A complement component 8, alpha polypeptide
C9ORF156 chromosome 9 open reading frame 156
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALHM2 calcium homeostasis modulator 2
CARD9 caspase recruitment domain family, member 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL21 chemokine (C-C motif) ligand 21
CD40LG CD40 ligand
CDC14B cell division cycle 14B
CDK10 cyclin-dependent kinase 10
CFLAR CASP8 and FADD-like apoptosis regulator
CNTFR ciliary neurotrophic factor receptor
CXCR4 chemokine (C-X-C motif) receptor 4
DFNB31 deafness, autosomal recessive 31
DST dystonin
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDRF1 erythroid differentiation regulatory factor 1
ERN1 endoplasmic reticulum to nucleus signaling 1
FAS Fas cell surface death receptor
FBXO22 F-box protein 22
FUZ fuzzy planar cell polarity protein
GJA8 gap junction protein, alpha 8, 50kDa
GK3P glycerol kinase 3 pseudogene
HABP4 hyaluronan binding protein 4
HEATR6 HEAT repeat containing 6
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HIST1H2BO histone cluster 1, H2bo
HIST1H4H histone cluster 1, H4h
HPCAL4 hippocalcin like 4
IGHA1 immunoglobulin heavy constant alpha 1
IL12A interleukin 12A
IL18R1 interleukin 18 receptor 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KRT4 keratin 4, type II
LCT lactase
LDB2 LIM domain binding 2
LGALS8 lectin, galactoside-binding, soluble, 8
LIPG lipase, endothelial
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LPIN2 lipin 2
MAP7 microtubule-associated protein 7
MED16 mediator complex subunit 16
METTL7A methyltransferase like 7A
MLN motilin
MYBPC3 myosin binding protein C, cardiac
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NCF4 neutrophil cytosolic factor 4, 40kDa
NDRG2 NDRG family member 2
NOX1 NADPH oxidase 1
NRG1 neuregulin 1
NRN1 neuritin 1
OLFML2B olfactomedin-like 2B
PAWR PRKC, apoptosis, WT1, regulator
PDE10A phosphodiesterase 10A
PEX26 peroxisomal biogenesis factor 26
PKP4 plakophilin 4
PLA2G1B phospholipase A2, group IB (pancreas)
PLCL2 phospholipase C-like 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PQLC2 PQ loop repeat containing 2
PRKG1 protein kinase, cGMP-dependent, type I
RPA4 replication protein A4, 30kDa
RXRB retinoid X receptor, beta
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SGSM3 small G protein signaling modulator 3
SMAD4 SMAD family member 4
STON1 stonin 1
TBRG4 transforming growth factor beta regulator 4
TBXA2R thromboxane A2 receptor
TFCP2L1 transcription factor CP2-like 1
THBD thrombomodulin
THRB thyroid hormone receptor, beta
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC6 transmembrane channel-like 6
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TTLL4 tubulin tyrosine ligase-like family member 4
TUBA3C tubulin, alpha 3c
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VGF VGF nerve growth factor inducible
VN1R1 vomeronasal 1 receptor 1
ZBTB18 zinc finger and BTB domain containing 18
ZNF235 zinc finger protein 235
ZNF334 zinc finger protein 334
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
AMDHD2 amidohydrolase domain containing 2
APOC4 apolipoprotein C-IV
ARPIN actin-related protein 2/3 complex inhibitor
AXIN1 axin 1
BFSP1 beaded filament structural protein 1, filensin
BST1 bone marrow stromal cell antigen 1
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF105 chromosome 1 open reading frame 105
CA9 carbonic anhydrase IX
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCNO cyclin O
CD68 CD68 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDON cell adhesion associated, oncogene regulated
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L2 chitinase 3-like 2
CNGB3 cyclic nucleotide gated channel beta 3
COG4 component of oligomeric golgi complex 4
CORO1A coronin, actin binding protein, 1A
CPED1 cadherin-like and PC-esterase domain containing 1
CPNE7 copine VII
CRELD1 cysteine-rich with EGF-like domains 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUZD1 CUB and zona pellucida-like domains 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DDN dendrin
DMBT1 deleted in malignant brain tumors 1
DNAL4 dynein, axonemal, light chain 4
EFNB1 ephrin-B1
EPN1 epsin 1
EXO5 exonuclease 5
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GRAMD1C GRAM domain containing 1C
GTPBP2 GTP binding protein 2
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
IRF2BP1 interferon regulatory factor 2 binding protein 1
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KRT33A keratin 33A, type I
LAMC3 laminin, gamma 3
LMTK1 lemur tail kinase 1
LPAR4 lysophosphatidic acid receptor 4
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MAST3 microtubule associated serine/threonine kinase 3
MFSD10 major facilitator superfamily domain containing 10
MFSD11 major facilitator superfamily domain containing 11
MMP3 matrix metallopeptidase 3
MON1B MON1 secretory trafficking family member B
MYO1F myosin IF
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NIPAL2 NIPA-like domain containing 2
NUP62CL nucleoporin 62kDa C-terminal like
OASL 2'-5'-oligoadenylate synthetase-like
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PADI1 peptidyl arginine deiminase, type I
PLAG1 pleiomorphic adenoma gene 1
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA3 plexin A3
QSER1 glutamine and serine rich 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RIMBP2 RIMS binding protein 2
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SARM1 sterile alpha and TIR motif containing 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLAMF7 SLAM family member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
STAB2 stabilin 2
SUGP1 SURP and G patch domain containing 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TLR2 toll-like receptor 2
TMC5 transmembrane channel-like 5
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
UBQLN4 ubiquilin 4
WDR25 WD repeat domain 25
XYLT2 xylosyltransferase II
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF268 zinc finger protein 268
ZNF358 zinc finger protein 358