| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the pronetalol-4104 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAM29 | ADAM metallopeptidase domain 29 |
| ADAM7 | ADAM metallopeptidase domain 7 |
| ADCK2 | aarF domain containing kinase 2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ATXN2L | ataxin 2-like |
| BCL3 | B-cell CLL/lymphoma 3 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC68 | coiled-coil domain containing 68 |
| CD58 | CD58 molecule |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CPQ | carboxypeptidase Q |
| CUL3 | cullin 3 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DCTN2 | dynactin 2 (p50) |
| DEPDC5 | DEP domain containing 5 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DPH5 | diphthamide biosynthesis 5 |
| DSG3 | desmoglein 3 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EFNB3 | ephrin-B3 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EN1 | engrailed homeobox 1 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FLOT1 | flotillin 1 |
| FRZB | frizzled-related protein |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GAS7 | growth arrest-specific 7 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPR143 | G protein-coupled receptor 143 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTM5 | glutathione S-transferase mu 5 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| ICOS | inducible T-cell co-stimulator |
| IGF1R | insulin-like growth factor 1 receptor |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| LAMC2 | laminin, gamma 2 |
| LOXL3 | lysyl oxidase-like 3 |
| MAL | mal, T-cell differentiation protein |
| MAPK7 | mitogen-activated protein kinase 7 |
| MATN3 | matrilin 3 |
| MMP13 | matrix metallopeptidase 13 |
| MORC1 | MORC family CW-type zinc finger 1 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAPPA2 | pappalysin 2 |
| PCNX | pecanex homolog (Drosophila) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PLLP | plasmolipin |
| PLXNA2 | plexin A2 |
| PRKCQ | protein kinase C, theta |
| PTHLH | parathyroid hormone-like hormone |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RND1 | Rho family GTPase 1 |
| RPL14 | ribosomal protein L14 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RSU1 | Ras suppressor protein 1 |
| SECTM1 | secreted and transmembrane 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| SYP | synaptophysin |
| SYT11 | synaptotagmin XI |
| TBC1D2 | TBC1 domain family, member 2 |
| TCF3 | transcription factor 3 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMEM144 | transmembrane protein 144 |
| TRIM38 | tripartite motif containing 38 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBOX5 | U-box domain containing 5 |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WSCD1 | WSC domain containing 1 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF318 | zinc finger protein 318 |
| ZNF532 | zinc finger protein 532 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABHD4 | abhydrolase domain containing 4 |
| ACTL8 | actin-like 8 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| BMP15 | bone morphogenetic protein 15 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CBX8 | chromobox homolog 8 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNT1 | cyclin T1 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDHR2 | cadherin-related family member 2 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHST10 | carbohydrate sulfotransferase 10 |
| CPA4 | carboxypeptidase A4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4F | histone cluster 1, H4f |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HOXB2 | homeobox B2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGC12488 | |
| MIS18BP1 | MIS18 binding protein 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRR14L | proline rich 14-like |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS53 | protease, serine, 53 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFX7 | regulatory factor X, 7 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL10L | ribosomal protein L10-like |
| SAMD9 | sterile alpha motif domain containing 9 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMAD5 | SMAD family member 5 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPRYD7 | SPRY domain containing 7 |
| STK16 | serine/threonine kinase 16 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM19 | transmembrane protein 19 |
| TMEM209 | transmembrane protein 209 |
| TRIM16 | tripartite motif containing 16 |
| TUBA3D | tubulin, alpha 3d |
| USP36 | ubiquitin specific peptidase 36 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VASP | vasodilator-stimulated phosphoprotein |
| VGF | VGF nerve growth factor inducible |
| VIM | vimentin |
| XDH | xanthine dehydrogenase |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF134 | zinc finger protein 134 |
| ZNF652 | zinc finger protein 652 |
| ZNF74 | zinc finger protein 74 |
| ZNF747 | zinc finger protein 747 |
