| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
195 genes differentially expressed following the propafenone-5437 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 |
| ADD2 | adducin 2 (beta) |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CALD1 | caldesmon 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC64 | coiled-coil domain containing 64 |
| CDC42 | cell division cycle 42 |
| COL4A2 | collagen, type IV, alpha 2 |
| CRYGC | crystallin, gamma C |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DSG3 | desmoglein 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EDA | ectodysplasin A |
| FAM46C | family with sequence similarity 46, member C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO40 | F-box protein 40 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GCKR | glucokinase (hexokinase 4) regulator |
| GDF9 | growth differentiation factor 9 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HIST1H4E | histone cluster 1, H4e |
| HNF1B | HNF1 homeobox B |
| HSF1 | heat shock transcription factor 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF13B | kinesin family member 13B |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| LAG3 | lymphocyte-activation gene 3 |
| LOC644450 | uncharacterized LOC644450 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA5 | melanoma antigen family A5 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAOB | monoamine oxidase B |
| MAPK14 | mitogen-activated protein kinase 14 |
| MC5R | melanocortin 5 receptor |
| MECOM | MDS1 and EVI1 complex locus |
| MED25 | mediator complex subunit 25 |
| MFAP5 | microfibrillar associated protein 5 |
| NKX3-2 | NK3 homeobox 2 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NTNG1 | netrin G1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OCLM | oculomedin |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PDLIM3 | PDZ and LIM domain 3 |
| PEX6 | peroxisomal biogenesis factor 6 |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLAU | plasminogen activator, urokinase |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| POLM | polymerase (DNA directed), mu |
| POU2F3 | POU class 2 homeobox 3 |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAP2A | RAP2A, member of RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RUNDC3A | RUN domain containing 3A |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIRT5 | sirtuin 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TEF | thyrotrophic embryonic factor |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TLE4 | transducin-like enhancer of split 4 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRD | T cell receptor delta locus |
| TRIM31 | tripartite motif containing 31 |
| TSPAN9 | tetraspanin 9 |
| TYRP1 | tyrosinase-related protein 1 |
| USP22 | ubiquitin specific peptidase 22 |
| VSNL1 | visinin-like 1 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADORA2B | adenosine A2b receptor |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNO | cyclin O |
| CD82 | CD82 molecule |
| CD83 | CD83 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CUL9 | cullin 9 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EMID1 | EMI domain containing 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FLJ22184 | |
| FLT4 | fms-related tyrosine kinase 4 |
| FOSL1 | FOS-like antigen 1 |
| GLB1L | galactosidase, beta 1-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4A | histone cluster 1, H4a |
| IL17RA | interleukin 17 receptor A |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRX4 | iroquois homeobox 4 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0754 | KIAA0754 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MITF | microphthalmia-associated transcription factor |
| MPI | mannose phosphate isomerase |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1F | myosin IF |
| NCALD | neurocalcin delta |
| NES | nestin |
| NOL12 | nucleolar protein 12 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRKCE | protein kinase C, epsilon |
| RAD51AP1 | RAD51 associated protein 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF31 | ring finger protein 31 |
| RPGRIP1L | RPGRIP1-like |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| SDC3 | syndecan 3 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| SRPX | sushi-repeat containing protein, X-linked |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| TMEM104 | transmembrane protein 104 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRIM36 | tripartite motif containing 36 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| TWISTNB | TWIST neighbor |
| VEGFC | vascular endothelial growth factor C |
| XK | X-linked Kx blood group |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF430 | zinc finger protein 430 |
| ZNF446 | zinc finger protein 446 |
| ZNF480 | zinc finger protein 480 |
| ZNF652 | zinc finger protein 652 |
| ZNF813 | zinc finger protein 813 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
