propofol-3048 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

196 genes differentially expressed following the propofol-3048 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACHE acetylcholinesterase (Yt blood group)
ADRB1 adrenoceptor beta 1
AMACR alpha-methylacyl-CoA racemase
ANK2 ankyrin 2, neuronal
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP35 Rho GTPase activating protein 35
C16ORF70 chromosome 16 open reading frame 70
CADM3 cell adhesion molecule 3
CARD10 caspase recruitment domain family, member 10
CCDC92 coiled-coil domain containing 92
CD22 CD22 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLPS colipase, pancreatic
CNTFR ciliary neurotrophic factor receptor
COL10A1 collagen, type X, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
DLX2 distal-less homeobox 2
DNASE2 deoxyribonuclease II, lysosomal
EDN3 endothelin 3
EPS8L1 EPS8-like 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GJA9 gap junction protein, alpha 9, 59kDa
GPATCH4 G patch domain containing 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GSTTP1 glutathione S-transferase theta pseudogene 1
HLA-F major histocompatibility complex, class I, F
HOXB7 homeobox B7
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
IFI44 interferon-induced protein 44
IL36RN interleukin 36 receptor antagonist
IL6ST interleukin 6 signal transducer
ITGA9 integrin, alpha 9
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCTD17 potassium channel tetramerization domain containing 17
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHL23 kelch-like family member 23
KRT6B keratin 6B, type II
KRTAP1-3 keratin associated protein 1-3
KRTAP2-4 keratin associated protein 2-4
LAD1 ladinin 1
LHX2 LIM homeobox 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MAST4 microtubule associated serine/threonine kinase family member 4
MET MET proto-oncogene, receptor tyrosine kinase
MPPED2 metallophosphoesterase domain containing 2
MRPS12 mitochondrial ribosomal protein S12
MVD mevalonate (diphospho) decarboxylase
MYO7B myosin VIIB
NKX2-1 NK2 homeobox 1
NOX1 NADPH oxidase 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NRP1 neuropilin 1
OR10H1 olfactory receptor, family 10, subfamily H, member 1
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAX7 paired box 7
PCDHGC3 protocadherin gamma subfamily C, 3
PDE4DIP phosphodiesterase 4D interacting protein
PEG10 paternally expressed 10
PKP1 plakophilin 1
PLP1 proteolipid protein 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMEPA1 prostate transmembrane protein, androgen induced 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCA protein kinase C, alpha
PRY PTPN13-like, Y-linked
RDH8 retinol dehydrogenase 8 (all-trans)
RGS12 regulator of G-protein signaling 12
RGS20 regulator of G-protein signaling 20
RHAG Rh-associated glycoprotein
RRBP1 ribosome binding protein 1
SARM1 sterile alpha and TIR motif containing 1
SCIN scinderin
SH3BP1 SH3-domain binding protein 1
SIM2 single-minded family bHLH transcription factor 2
SIRPB1 signal-regulatory protein beta 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC39A9 solute carrier family 39, member 9
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
TAS2R4 taste receptor, type 2, member 4
TCEAL2 transcription elongation factor A (SII)-like 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMC7 transmembrane channel-like 7
TMCC1 transmembrane and coiled-coil domain family 1
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TPMT thiopurine S-methyltransferase
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TSHR thyroid stimulating hormone receptor
TSKU tsukushi, small leucine rich proteoglycan
UNC119 unc-119 homolog (C. elegans)
USP29 ubiquitin specific peptidase 29
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ADGRE3 adhesion G protein-coupled receptor E3
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARMCX4 armadillo repeat containing, X-linked 4
AXIN1 axin 1
BBC3 BCL2 binding component 3
BHLHE41 basic helix-loop-helix family, member e41
C14ORF105 chromosome 14 open reading frame 105
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
C1ORF35 chromosome 1 open reading frame 35
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
C9ORF3 chromosome 9 open reading frame 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CBR3 carbonyl reductase 3
CCL20 chemokine (C-C motif) ligand 20
CD300C CD300c molecule
CDR2L cerebellar degeneration-related protein 2-like
CHML choroideremia-like (Rab escort protein 2)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DPY19L1P1 DPY19L1 pseudogene 1
EMILIN2 elastin microfibril interfacer 2
FAM63A family with sequence similarity 63, member A
FER fer (fps/fes related) tyrosine kinase
FKBPL FK506 binding protein like
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GCH1 GTP cyclohydrolase 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIF gastric intrinsic factor (vitamin B synthesis)
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GRIP2 glutamate receptor interacting protein 2
GSTA4 glutathione S-transferase alpha 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H1B histone cluster 1, H1b
HIST1H3G histone cluster 1, H3g
HRH1 histamine receptor H1
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
IFT140 intraflagellar transport 140
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
KIAA1107 KIAA1107
KLHL28 kelch-like family member 28
KPTN kaptin (actin binding protein)
LIN7A lin-7 homolog A (C. elegans)
LOXL3 lysyl oxidase-like 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
MAGEH1 melanoma antigen family H1
MANSC1 MANSC domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MUC2 mucin 2, oligomeric mucus/gel-forming
NEK11 NIMA-related kinase 11
NNAT neuronatin
NOL10 nucleolar protein 10
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PER3 period circadian clock 3
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRB3 proline-rich protein BstNI subfamily 3
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB17 RAB17, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHOB ras homolog family member B
RPL23AP53 ribosomal protein L23a pseudogene 53
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SERINC5 serine incorporator 5
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SETD1A SET domain containing 1A
SH2D3C SH2 domain containing 3C
SH3BGR SH3 domain binding glutamate-rich protein
SHPK sedoheptulokinase
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC16A4 solute carrier family 16, member 4
SLC16A6 solute carrier family 16, member 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THBS4 thrombospondin 4
TLR1 toll-like receptor 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM242 transmembrane protein 242
TNS2 tensin 2
TONSL tonsoku-like, DNA repair protein
TSC22D4 TSC22 domain family, member 4
USP27X ubiquitin specific peptidase 27, X-linked
ZBTB25 zinc finger and BTB domain containing 25
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF225 zinc finger protein 225
ZNF354A zinc finger protein 354A
ZNF428 zinc finger protein 428
ZNF821 zinc finger protein 821
ZNHIT2 zinc finger, HIT-type containing 2