| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the propofol-3386 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ATF3 | activating transcription factor 3 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C19ORF57 | chromosome 19 open reading frame 57 |
| CD47 | CD47 molecule |
| CD48 | CD48 molecule |
| CD83 | CD83 molecule |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CNTN5 | contactin 5 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR4 | early growth response 4 |
| EMP3 | epithelial membrane protein 3 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GM2A | GM2 ganglioside activator |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSTP1 | glutathione S-transferase pi 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3F | histone cluster 1, H3f |
| HIST1H4H | histone cluster 1, H4h |
| HMOX1 | heme oxygenase 1 |
| HOXA1 | homeobox A1 |
| HOXB5 | homeobox B5 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL1B | interleukin 1, beta |
| INHBE | inhibin, beta E |
| IRF1 | interferon regulatory factor 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGA8 | integrin, alpha 8 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KIAA1462 | KIAA1462 |
| KIF21B | kinesin family member 21B |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK14 | mitogen-activated protein kinase 14 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MPZ | myelin protein zero |
| MX1 | MX dynamin-like GTPase 1 |
| MXD1 | MAX dimerization protein 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PER1 | period circadian clock 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNMA3 | paraneoplastic Ma antigen 3 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RGS2 | regulator of G-protein signaling 2 |
| RUNX1 | runt-related transcription factor 1 |
| SCLY | selenocysteine lyase |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TEX14 | testis expressed 14 |
| TMEM59L | transmembrane protein 59-like |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRBC1 | T cell receptor beta constant 1 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTL8 | actin-like 8 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| AXIN1 | axin 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA11 | carbonic anhydrase XI |
| CAPN5 | calpain 5 |
| CDK18 | cyclin-dependent kinase 18 |
| CHKB | choline kinase beta |
| DBF4B | DBF4 zinc finger B |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM131A | family with sequence similarity 131, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR143 | G protein-coupled receptor 143 |
| GRAMD1C | GRAM domain containing 1C |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IFT22 | intraflagellar transport 22 |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| KIF13A | kinesin family member 13A |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LHX6 | LIM homeobox 6 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MBTD1 | mbt domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MST1R | macrophage stimulating 1 receptor |
| MTCP1 | mature T-cell proliferation 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NLRX1 | NLR family member X1 |
| NME5 | NME/NM23 family member 5 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHB3 | protocadherin beta 3 |
| PDE12 | phosphodiesterase 12 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PMP22 | peripheral myelin protein 22 |
| POLH | polymerase (DNA directed), eta |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STIM1 | stromal interaction molecule 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBKBP1 | TBK1 binding protein 1 |
| TEP1 | telomerase-associated protein 1 |
| TEX40 | testis expressed 40 |
| TMEM159 | transmembrane protein 159 |
| TMEM180 | transmembrane protein 180 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TUBA3C | tubulin, alpha 3c |
| UPK2 | uroplakin 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR76 | WD repeat domain 76 |
| WDR78 | WD repeat domain 78 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF136 | zinc finger protein 136 |
| ZNF205 | zinc finger protein 205 |
| ZNF423 | zinc finger protein 423 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF804A | zinc finger protein 804A |