propoxycaine-6161 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the propoxycaine-6161 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACP5 acid phosphatase 5, tartrate resistant
ADAM22 ADAM metallopeptidase domain 22
AGXT alanine-glyoxylate aminotransferase
AHNAK AHNAK nucleoprotein
AK1 adenylate kinase 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
APOC1 apolipoprotein C-I
APOE apolipoprotein E
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATP13A2 ATPase type 13A2
BCL3 B-cell CLL/lymphoma 3
C1ORF61 chromosome 1 open reading frame 61
C21ORF2 chromosome 21 open reading frame 2
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CD1A CD1a molecule
CEP164 centrosomal protein 164kDa
CHPF chondroitin polymerizing factor
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLCA2 chloride channel accessory 2
CLTA clathrin, light chain A
COL6A1 collagen, type VI, alpha 1
CREM cAMP responsive element modulator
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CUL7 cullin 7
DNAI2 dynein, axonemal, intermediate chain 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPEP2 dipeptidase 2
ELAC2 elaC ribonuclease Z 2
ELL elongation factor RNA polymerase II
EMP1 epithelial membrane protein 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPS8L1 EPS8-like 1
EXOSC2 exosome component 2
EXTL3 exostosin-like glycosyltransferase 3
FAIM2 Fas apoptotic inhibitory molecule 2
FASLG Fas ligand (TNF superfamily, member 6)
FGFR2 fibroblast growth factor receptor 2
GALR3 galanin receptor 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPATCH4 G patch domain containing 4
GPR15 G protein-coupled receptor 15
GPR35 G protein-coupled receptor 35
GPX3 glutathione peroxidase 3
GRM1 glutamate receptor, metabotropic 1
HAB1 B1 for mucin
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIST1H1D histone cluster 1, H1d
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXB7 homeobox B7
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGFBP5 insulin-like growth factor binding protein 5
IPP intracisternal A particle-promoted polypeptide
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KRT17 keratin 17, type I
LARGE like-glycosyltransferase
LRP4 low density lipoprotein receptor-related protein 4
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MCM3AP minichromosome maintenance complex component 3 associated protein
MKRN3 makorin ring finger protein 3
MYO7A myosin VIIA
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NPC1 Niemann-Pick disease, type C1
NRCAM neuronal cell adhesion molecule
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PCGF2 polycomb group ring finger 2
PCNXL2 pecanex-like 2 (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PER1 period circadian clock 1
PER3 period circadian clock 3
PIGR polymeric immunoglobulin receptor
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPT2 palmitoyl-protein thioesterase 2
PRSS21 protease, serine, 21 (testisin)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RCAN2 regulator of calcineurin 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SP1 Sp1 transcription factor
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SSTR5 somatostatin receptor 5
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TUBD1 tubulin, delta 1
USB1 U6 snRNA biogenesis 1
WTAP Wilms tumor 1 associated protein
YPEL1 yippee-like 1 (Drosophila)
ZNF132 zinc finger protein 132
ZNF215 zinc finger protein 215
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ARMC4 armadillo repeat containing 4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BHLHE41 basic helix-loop-helix family, member e41
BIRC3 baculoviral IAP repeat containing 3
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF63 chromosome 11 open reading frame 63
C7ORF69 chromosome 7 open reading frame 69
CCL20 chemokine (C-C motif) ligand 20
CD1C CD1c molecule
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CELP carboxyl ester lipase pseudogene
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CORT cortistatin
CRABP2 cellular retinoic acid binding protein 2
CRY2 cryptochrome circadian clock 2
DENND4C DENN/MADD domain containing 4C
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNMBP dynamin binding protein
DSPP dentin sialophosphoprotein
DTX4 deltex 4, E3 ubiquitin ligase
ENO3 enolase 3 (beta, muscle)
ETV4 ets variant 4
FBXL7 F-box and leucine-rich repeat protein 7
FGFBP1 fibroblast growth factor binding protein 1
GK3P glycerol kinase 3 pseudogene
GLTSCR1 glioma tumor suppressor candidate region gene 1
GP6 glycoprotein VI (platelet)
GSTCD glutathione S-transferase, C-terminal domain containing
HCAR3 hydroxycarboxylic acid receptor 3
IFNA14 interferon, alpha 14
IGFBP4 insulin-like growth factor binding protein 4
IGLV1-44 immunoglobulin lambda variable 1-44
IL12B interleukin 12B
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1024 KIAA1024
KIAA1107 KIAA1107
KLF1 Kruppel-like factor 1 (erythroid)
LIME1 Lck interacting transmembrane adaptor 1
LOC100287590 uncharacterized LOC100287590
LOC730101 uncharacterized LOC730101
LOXL3 lysyl oxidase-like 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBOAT2 membrane bound O-acyltransferase domain containing 2
MEGF8 multiple EGF-like-domains 8
MNX1 motor neuron and pancreas homeobox 1
MXD3 MAX dimerization protein 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDHGB5 protocadherin gamma subfamily B, 5
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PYGB phosphorylase, glycogen; brain
RAB13 RAB13, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RETN resistin
RFPL3 ret finger protein-like 3
RNF126P1 ring finger protein 126 pseudogene 1
RPL13P5 ribosomal protein L13 pseudogene 5
SEC31B SEC31 homolog B (S. cerevisiae)
SIK1 salt-inducible kinase 1
SLC12A9 solute carrier family 12, member 9
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMR3A submaxillary gland androgen regulated protein 3A
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STX1A syntaxin 1A (brain)
TAS2R10 taste receptor, type 2, member 10
TGFBR3 transforming growth factor, beta receptor III
TMEM140 transmembrane protein 140
TMEM212 transmembrane protein 212
TMEM254 transmembrane protein 254
TNNT1 troponin T type 1 (skeletal, slow)
TNS2 tensin 2
TP53I3 tumor protein p53 inducible protein 3
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TSPAN13 tetraspanin 13
UNC119 unc-119 homolog (C. elegans)
ZBTB22 zinc finger and BTB domain containing 22
ZIC3 Zic family member 3
ZNF155 zinc finger protein 155
ZNF177 zinc finger protein 177
ZNF223 zinc finger protein 223
ZNF32 zinc finger protein 32
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZNRD1-AS1 ZNRD1 antisense RNA 1