propoxycaine-6803 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the propoxycaine-6803 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
AIM1L absent in melanoma 1-like
AKAP4 A kinase (PRKA) anchor protein 4
ALS2CL ALS2 C-terminal like
AMPD3 adenosine monophosphate deaminase 3
ATF6B activating transcription factor 6 beta
BTF3P11 basic transcription factor 3 pseudogene 11
C3 complement component 3
CA4 carbonic anhydrase IV
CACFD1 calcium channel flower domain containing 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMP cathelicidin antimicrobial peptide
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC25C cell division cycle 25C
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP164 centrosomal protein 164kDa
CHKB choline kinase beta
CLCN7 chloride channel, voltage-sensitive 7
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CTAG2 cancer/testis antigen 2
CXCR4 chemokine (C-X-C motif) receptor 4
DLL3 delta-like 3 (Drosophila)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EMID1 EMI domain containing 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPS8L3 EPS8-like 3
FAM212B family with sequence similarity 212, member B
FBLN1 fibulin 1
FBXO41 F-box protein 41
FCAR Fc fragment of IgA receptor
FGL2 fibrinogen-like 2
FSCN3 fascin actin-bundling protein 3, testicular
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GFER growth factor, augmenter of liver regeneration
GJA8 gap junction protein, alpha 8, 50kDa
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPC3 glypican 3
GPR153 G protein-coupled receptor 153
HPCAL4 hippocalcin like 4
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
IDUA iduronidase, alpha-L-
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IL1B interleukin 1, beta
IL24 interleukin 24
IL6R interleukin 6 receptor
IRF4 interferon regulatory factor 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LIN7A lin-7 homolog A (C. elegans)
LRP12 low density lipoprotein receptor-related protein 12
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LUZP4 leucine zipper protein 4
MARK2 MAP/microtubule affinity-regulating kinase 2
MEF2C myocyte enhancer factor 2C
MOCS1 molybdenum cofactor synthesis 1
MRAS muscle RAS oncogene homolog
NOP16 NOP16 nucleolar protein
NPTX1 neuronal pentraxin I
NRSN2 neurensin 2
OTUD7B OTU deubiquitinase 7B
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRB4 proline-rich protein BstNI subfamily 4
PRSS50 protease, serine, 50
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRM protein tyrosine phosphatase, receptor type, M
PYY peptide YY
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RGS10 regulator of G-protein signaling 10
RTEL1 regulator of telomere elongation helicase 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SHOX2 short stature homeobox 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SNTG1 syntrophin, gamma 1
SRCAP Snf2-related CREBBP activator protein
STAB1 stabilin 1
STAG3 stromal antigen 3
SYNC syncoilin, intermediate filament protein
TBC1D2 TBC1 domain family, member 2
TCF25 transcription factor 25 (basic helix-loop-helix)
TCP11L1 t-complex 11, testis-specific-like 1
TMPRSS4 transmembrane protease, serine 4
TPMT thiopurine S-methyltransferase
ULK2 unc-51 like autophagy activating kinase 2
UPK3B uroplakin 3B
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZC3H7B zinc finger CCCH-type containing 7B
ZNF202 zinc finger protein 202
ZNF280A zinc finger protein 280A
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGO3 argonaute RISC catalytic component 3
AKAP12 A kinase (PRKA) anchor protein 12
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANKRD40 ankyrin repeat domain 40
ARC activity-regulated cytoskeleton-associated protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASB7 ankyrin repeat and SOCS box containing 7
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCORL1 BCL6 corepressor-like 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C7ORF43 chromosome 7 open reading frame 43
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CCNO cyclin O
CD302 CD302 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CLCN5 chloride channel, voltage-sensitive 5
CROT carnitine O-octanoyltransferase
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DOCK1 dedicator of cytokinesis 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF5A2 eukaryotic translation initiation factor 5A2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FKBP14 FK506 binding protein 14, 22 kDa
FZD2 frizzled class receptor 2
GAMT guanidinoacetate N-methyltransferase
GPALPP1 GPALPP motifs containing 1
GPR27 G protein-coupled receptor 27
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUSBP3 glucuronidase, beta pseudogene 3
GYS1 glycogen synthase 1 (muscle)
HIRIP3 HIRA interacting protein 3
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIZ kizuna centrosomal protein
L2HGDH L-2-hydroxyglutarate dehydrogenase
LRRC61 leucine rich repeat containing 61
METTL8 methyltransferase like 8
MOAP1 modulator of apoptosis 1
MORC3 MORC family CW-type zinc finger 3
MRPL52 mitochondrial ribosomal protein L52
NNAT neuronatin
NPY5R neuropeptide Y receptor Y5
NT5E 5'-nucleotidase, ecto (CD73)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP16 poly (ADP-ribose) polymerase family, member 16
PCNXL4 pecanex-like 4 (Drosophila)
PGP phosphoglycolate phosphatase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNA3 plexin A3
PODXL2 podocalyxin-like 2
PRMT7 protein arginine methyltransferase 7
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI14 retinoic acid induced 14
RGS17 regulator of G-protein signaling 17
SIRAL2 SIR2 antiphage like 2
SLC12A9 solute carrier family 12, member 9
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SOBP sine oculis binding protein homolog (Drosophila)
SP1 Sp1 transcription factor
SPATA7 spermatogenesis associated 7
STBD1 starch binding domain 1
TCTN1 tectonic family member 1
TEP1 telomerase-associated protein 1
THBS3 thrombospondin 3
TMEM115 transmembrane protein 115
TRAPPC6A trafficking protein particle complex 6A
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPYL2 TSPY-like 2
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC33 tetratricopeptide repeat domain 33
USB1 U6 snRNA biogenesis 1
VN1R1 vomeronasal 1 receptor 1
WDR25 WD repeat domain 25
ZBTB22 zinc finger and BTB domain containing 22
ZBTB6 zinc finger and BTB domain containing 6
ZFP69B ZFP69 zinc finger protein B
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF219 zinc finger protein 219
ZNF227 zinc finger protein 227
ZNF365 zinc finger protein 365
ZNF442 zinc finger protein 442
ZNF510 zinc finger protein 510
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675