propranolol-3059 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the propranolol-3059 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKAP9 A kinase (PRKA) anchor protein 9
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCAS3 breast carcinoma amplified sequence 3
BMP7 bone morphogenetic protein 7
BMP8A bone morphogenetic protein 8a
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNC2 basonuclin 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUD31 BUD31 homolog (S. cerevisiae)
C10ORF95 chromosome 10 open reading frame 95
C11ORF16 chromosome 11 open reading frame 16
C17ORF59 chromosome 17 open reading frame 59
C2CD2L C2CD2-like
CA6 carbonic anhydrase VI
CCL22 chemokine (C-C motif) ligand 22
CD6 CD6 molecule
CEP250 centrosomal protein 250kDa
COL10A1 collagen, type X, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPN2 carboxypeptidase N, polypeptide 2
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTC1 CTS telomere maintenance complex component 1
DCLK2 doublecortin-like kinase 2
DLX2 distal-less homeobox 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
ECE1 endothelin converting enzyme 1
EPX eosinophil peroxidase
ESR1 estrogen receptor 1
EXT1 exostosin glycosyltransferase 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FGFBP1 fibroblast growth factor binding protein 1
FLOT1 flotillin 1
FSTL4 follistatin-like 4
FZD4 frizzled class receptor 4
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GNAS GNAS complex locus
GPR4 G protein-coupled receptor 4
GREM1 gremlin 1, DAN family BMP antagonist
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
IL1R1 interleukin 1 receptor, type I
IL36RN interleukin 36 receptor antagonist
IQSEC1 IQ motif and Sec7 domain 1
KIF5C kinesin family member 5C
KLF12 Kruppel-like factor 12
LEFTY1 left-right determination factor 1
LIG3 ligase III, DNA, ATP-dependent
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMNA lamin A/C
MAP9 microtubule-associated protein 9
MAPK7 mitogen-activated protein kinase 7
MBL2 mannose-binding lectin (protein C) 2, soluble
MINK1 misshapen-like kinase 1
MTUS1 microtubule associated tumor suppressor 1
MXD4 MAX dimerization protein 4
MYF5 myogenic factor 5
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OPCML opioid binding protein/cell adhesion molecule-like
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTOF otoferlin
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PCSK6 proprotein convertase subtilisin/kexin type 6
PLIN2 perilipin 2
PODXL podocalyxin-like
PRLR prolactin receptor
PTRF polymerase I and transcript release factor
PYGB phosphorylase, glycogen; brain
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RERE arginine-glutamic acid dipeptide (RE) repeats
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIM2 single-minded family bHLH transcription factor 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMTN smoothelin
SORBS2 sorbin and SH3 domain containing 2
SOX15 SRY (sex determining region Y)-box 15
SPANXC SPANX family, member C
SRPX2 sushi-repeat containing protein, X-linked 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TACR1 tachykinin receptor 1
TGM1 transglutaminase 1
TIMELESS timeless circadian clock
TMEM257 transmembrane protein 257
TRIO trio Rho guanine nucleotide exchange factor
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPC7 transient receptor potential cation channel, subfamily C, member 7
ZNF518A zinc finger protein 518A
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGB androglobin
ADGRB1 adhesion G protein-coupled receptor B1
ADORA3 adenosine A3 receptor
AHDC1 AT hook, DNA binding motif, containing 1
AMPH amphiphysin
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BBC3 BCL2 binding component 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BHMT2 betaine--homocysteine S-methyltransferase 2
C16ORF59 chromosome 16 open reading frame 59
C17ORF53 chromosome 17 open reading frame 53
C9ORF3 chromosome 9 open reading frame 3
C9ORF9 chromosome 9 open reading frame 9
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCRL2 chemokine (C-C motif) receptor-like 2
CD34 CD34 molecule
CD37 CD37 molecule
CD82 CD82 molecule
CD9 CD9 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLCF1 cardiotrophin-like cytokine factor 1
CLEC4E C-type lectin domain family 4, member E
COL19A1 collagen, type XIX, alpha 1
DTX2 deltex 2, E3 ubiquitin ligase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ERCC6 excision repair cross-complementation group 6
ERICH1 glutamate-rich 1
FAM106A family with sequence similarity 106, member A
FAM131A family with sequence similarity 131, member A
FHL3 four and a half LIM domains 3
FOXO4 forkhead box O4
FRMPD1 FERM and PDZ domain containing 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPC3 glypican 3
GZMK granzyme K (granzyme 3; tryptase II)
HIST1H1B histone cluster 1, H1b
HRAS Harvey rat sarcoma viral oncogene homolog
HYAL2 hyaluronoglucosaminidase 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
JPH3 junctophilin 3
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA0319L KIAA0319-like
KPTN kaptin (actin binding protein)
LINC00260 long intergenic non-protein coding RNA 260
LOC57399 uncharacterized gastric protein ZA52P
LRP5 low density lipoprotein receptor-related protein 5
LRRC6 leucine rich repeat containing 6
LSP1 lymphocyte-specific protein 1
MEP1B meprin A, beta
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NOD1 nucleotide-binding oligomerization domain containing 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTN1 netrin 1
NTSR1 neurotensin receptor 1 (high affinity)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI1 peptidyl arginine deiminase, type I
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKN1 protein kinase N1
PLD2 phospholipase D2
PROCR protein C receptor, endothelial
PTDSS2 phosphatidylserine synthase 2
RAB3A RAB3A, member RAS oncogene family
RGS13 regulator of G-protein signaling 13
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC35E3 solute carrier family 35, member E3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMR3B submaxillary gland androgen regulated protein 3B
SPATA20 spermatogenesis associated 20
SRPX sushi-repeat containing protein, X-linked
STAB2 stabilin 2
SYCP2 synaptonemal complex protein 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D19 TBC1 domain family, member 19
TFDP3 transcription factor Dp family, member 3
TICAM1 toll-like receptor adaptor molecule 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
TSPAN2 tetraspanin 2
TUBA3C tubulin, alpha 3c
UBL4A ubiquitin-like 4A
UNC13A unc-13 homolog A (C. elegans)
ZBTB22 zinc finger and BTB domain containing 22
ZBTB6 zinc finger and BTB domain containing 6
ZNF219 zinc finger protein 219
ZNF415 zinc finger protein 415
ZNF442 zinc finger protein 442
ZNF484 zinc finger protein 484
ZNF711 zinc finger protein 711