propranolol-6759 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the propranolol-6759 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY6 adenylate cyclase 6
AKR1C4 aldo-keto reductase family 1, member C4
ARHGAP33 Rho GTPase activating protein 33
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP10 bone morphogenetic protein 10
BTN3A1 butyrophilin, subfamily 3, member A1
C21ORF2 chromosome 21 open reading frame 2
C9ORF9 chromosome 9 open reading frame 9
CATR1 CATR tumorigenicity conversion 1
CCL2 chemokine (C-C motif) ligand 2
CD58 CD58 molecule
CDC14A cell division cycle 14A
CELA2B chymotrypsin-like elastase family, member 2B
CEP68 centrosomal protein 68kDa
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLCN7 chloride channel, voltage-sensitive 7
CNPY4 canopy FGF signaling regulator 4
CT55 cancer/testis antigen 55
CYTH3 cytohesin 3
DBF4B DBF4 zinc finger B
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCHS2 dachsous cadherin-related 2
DCLK2 doublecortin-like kinase 2
DCX doublecortin
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
E2F4 E2F transcription factor 4, p107/p130-binding
EDA ectodysplasin A
ESR1 estrogen receptor 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXO21 F-box protein 21
FBXO22 F-box protein 22
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GFI1 growth factor independent 1 transcription repressor
GHRHR growth hormone releasing hormone receptor
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA8A golgin A8 family, member A
GP6 glycoprotein VI (platelet)
GPR35 G protein-coupled receptor 35
GSN-AS1 GSN antisense RNA 1
HAP1 huntingtin-associated protein 1
HIST1H4D histone cluster 1, H4d
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL37 interleukin 37
ING4 inhibitor of growth family, member 4
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JPH3 junctophilin 3
KIAA0087 KIAA0087
KIF25 kinesin family member 25
MST1 macrophage stimulating 1
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NOP14-AS1 NOP14 antisense RNA 1
NRG1 neuregulin 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PACRG PARK2 co-regulated
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDH11Y protocadherin 11 Y-linked
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGA3 protocadherin gamma subfamily A, 3
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4A phosphodiesterase 4A, cAMP-specific
PEX5L peroxisomal biogenesis factor 5-like
PGK2 phosphoglycerate kinase 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRUNE2 prune homolog 2 (Drosophila)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RARA retinoic acid receptor, alpha
RASAL2 RAS protein activator like 2
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBBP9 retinoblastoma binding protein 9
REEP2 receptor accessory protein 2
RUNDC3B RUN domain containing 3B
RUNX1 runt-related transcription factor 1
S100A13 S100 calcium binding protein A13
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFRP4 secreted frizzled-related protein 4
SH3BP2 SH3-domain binding protein 2
SIRAL2 SIR2 antiphage like 2
SLA Src-like-adaptor
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SOGA1 suppressor of glucose, autophagy associated 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TAPT1 transmembrane anterior posterior transformation 1
TFEB transcription factor EB
TFEC transcription factor EC
TK2 thymidine kinase 2, mitochondrial
TMEM231 transmembrane protein 231
TRO trophinin
TTC30A tetratricopeptide repeat domain 30A
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
APOC4 apolipoprotein C-IV
ARMCX4 armadillo repeat containing, X-linked 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C9ORF40 chromosome 9 open reading frame 40
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMKMT calmodulin-lysine N-methyltransferase
CARTPT CART prepropeptide
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CCDC85C coiled-coil domain containing 85C
CLCA1 chloride channel accessory 1
CNN1 calponin 1, basic, smooth muscle
CRMP1 collapsin response mediator protein 1
CSF1R colony stimulating factor 1 receptor
DLK2 delta-like 2 homolog (Drosophila)
DNM3 dynamin 3
DTX2 deltex 2, E3 ubiquitin ligase
EGR2 early growth response 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
FBRS fibrosin
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FRMD8 FERM domain containing 8
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GATA4 GATA binding protein 4
GRB7 growth factor receptor-bound protein 7
GREB1L growth regulation by estrogen in breast cancer-like
GRM4 glutamate receptor, metabotropic 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HESX1 HESX homeobox 1
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H3C histone cluster 1, H3c
HOXA4 homeobox A4
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ICOS inducible T-cell co-stimulator
IL36RN interleukin 36 receptor antagonist
IL6 interleukin 6
INPPL1 inositol polyphosphate phosphatase-like 1
IPO8 importin 8
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT20 keratin 20, type I
KRT34 keratin 34, type I
LIFR leukemia inhibitory factor receptor alpha
LIME1 Lck interacting transmembrane adaptor 1
LINS lines homolog (Drosophila)
LMCD1 LIM and cysteine-rich domains 1
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MAP3K7CL MAP3K7 C-terminal like
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MOCS3 molybdenum cofactor synthesis 3
MYLIP myosin regulatory light chain interacting protein
NEUROD1 neuronal differentiation 1
NKX3-2 NK3 homeobox 2
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCA2 oculocutaneous albinism II
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PARPBP PARP1 binding protein
PDIA3 protein disulfide isomerase family A, member 3
PMCH pro-melanin-concentrating hormone
PRAMEF10 PRAME family member 10
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTPRS protein tyrosine phosphatase, receptor type, S
QSER1 glutamine and serine rich 1
RAG2 recombination activating gene 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RPGRIP1L RPGRIP1-like
SLC16A6 solute carrier family 16, member 6
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNTG1 syntrophin, gamma 1
SP1 Sp1 transcription factor
SPATA1 spermatogenesis associated 1
SPRYD7 SPRY domain containing 7
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D22B TBC1 domain family, member 22B
TBXAS1 thromboxane A synthase 1 (platelet)
TEX40 testis expressed 40
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TMEM19 transmembrane protein 19
UGT8 UDP glycosyltransferase 8
VGF VGF nerve growth factor inducible
WNT10B wingless-type MMTV integration site family, member 10B
YOD1 YOD1 deubiquitinase
YY2 YY2 transcription factor
ZNF137P zinc finger protein 137, pseudogene
ZNF253 zinc finger protein 253
ZNF471 zinc finger protein 471
ZW10 zw10 kinetochore protein
ZXDB zinc finger, X-linked, duplicated B