propylthiouracil-2476 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the propylthiouracil-2476 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABAT 4-aminobutyrate aminotransferase
AGER advanced glycosylation end product-specific receptor
ANKLE2 ankyrin repeat and LEM domain containing 2
APOL2 apolipoprotein L, 2
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BCL2 B-cell CLL/lymphoma 2
BMP1 bone morphogenetic protein 1
C19ORF73 chromosome 19 open reading frame 73
CD200 CD200 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDO1 cysteine dioxygenase type 1
CNPY4 canopy FGF signaling regulator 4
CNTN5 contactin 5
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL18A1 collagen, type XVIII, alpha 1
COL19A1 collagen, type XIX, alpha 1
CREM cAMP responsive element modulator
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTSF cathepsin F
DLX2 distal-less homeobox 2
EFNA4 ephrin-A4
EMC3 ER membrane protein complex subunit 3
ERC2-IT1 ERC2 intronic transcript 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FADS3 fatty acid desaturase 3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GPR182 G protein-coupled receptor 182
GPX2 glutathione peroxidase 2
GTDC1 glycosyltransferase-like domain containing 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HMGN5 high mobility group nucleosome binding domain 5
HRH3 histamine receptor H3
IGLV1-44 immunoglobulin lambda variable 1-44
IL2 interleukin 2
IQCK IQ motif containing K
ISL1 ISL LIM homeobox 1
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNIP1 Kv channel interacting protein 1
KIF1C kinesin family member 1C
KLK7 kallikrein-related peptidase 7
KRT9 keratin 9, type I
LMF1 lipase maturation factor 1
LMTK2 lemur tyrosine kinase 2
LPAR3 lysophosphatidic acid receptor 3
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
LY6E lymphocyte antigen 6 complex, locus E
MAN1A2 mannosidase, alpha, class 1A, member 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MNMIP1 manchette microtubule inner protein 1
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MTNR1A melatonin receptor 1A
MYT1L myelin transcription factor 1-like
NCLN nicalin
NOVA2 neuro-oncological ventral antigen 2
NRXN1 neurexin 1
PAIP2B poly(A) binding protein interacting protein 2B
PAX5 paired box 5
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCH1 phospholipase C, eta 1
PLEC plectin
POFUT2 protein O-fucosyltransferase 2
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PTCRA pre T-cell antigen receptor alpha
RAB6B RAB6B, member RAS oncogene family
RARA retinoic acid receptor, alpha
REPS1 RALBP1 associated Eps domain containing 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPL7 ribosomal protein L7
RUFY3 RUN and FYVE domain containing 3
SCN10A sodium channel, voltage gated, type X alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPDEF SAM pointed domain containing ETS transcription factor
SPTAN1 spectrin, alpha, non-erythrocytic 1
STC1 stanniocalcin 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEF thyrotrophic embryonic factor
TLN2 talin 2
TMEM63A transmembrane protein 63A
TNNT3 troponin T type 3 (skeletal, fast)
TRAF1 TNF receptor-associated factor 1
TRGV5 T cell receptor gamma variable 5
TSGA10 testis specific, 10
TWF1 twinfilin actin binding protein 1
UBE2I ubiquitin-conjugating enzyme E2I
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UPK2 uroplakin 2
USP18 ubiquitin specific peptidase 18
WNT16 wingless-type MMTV integration site family, member 16
ZNF3 zinc finger protein 3

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
ADTRP androgen-dependent TFPI-regulating protein
AEN apoptosis enhancing nuclease
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
ANKRD55 ankyrin repeat domain 55
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGAP12 Rho GTPase activating protein 12
ARMC6 armadillo repeat containing 6
BAMBI BMP and activin membrane-bound inhibitor
BNC2 basonuclin 2
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
CBX4 chromobox homolog 4
CD82 CD82 molecule
CDC37L1 cell division cycle 37-like 1
CDK3 cyclin-dependent kinase 3
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLCN2 chloride channel, voltage-sensitive 2
CRY2 cryptochrome circadian clock 2
CTDNEP1 CTD nuclear envelope phosphatase 1
CTSO cathepsin O
DSPP dentin sialophosphoprotein
EFNA3 ephrin-A3
EGR2 early growth response 2
FAM3A family with sequence similarity 3, member A
G0S2 G0/G1 switch 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPR19 G protein-coupled receptor 19
GPR85 G protein-coupled receptor 85
GRIP2 glutamate receptor interacting protein 2
GRWD1 glutamate-rich WD repeat containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HP haptoglobin
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL3RA interleukin 3 receptor, alpha (low affinity)
INCENP inner centromere protein antigens 135/155kDa
KCTD7 potassium channel tetramerization domain containing 7
KIAA0196 KIAA0196
KIAA1107 KIAA1107
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LRP2 low density lipoprotein receptor-related protein 2
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MANSC1 MANSC domain containing 1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCOLN1 mucolipin 1
MIS18BP1 MIS18 binding protein 1
MRAS muscle RAS oncogene homolog
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR7 proline rich 7 (synaptic)
REC8 REC8 meiotic recombination protein
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SHARPIN SHANK-associated RH domain interactor
SLC22A14 solute carrier family 22, member 14
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX16 sorting nexin 16
SNX29P2 sorting nexin 29 pseudogene 2
SPATS2 spermatogenesis associated, serine-rich 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STX11 syntaxin 11
SYNC syncoilin, intermediate filament protein
SYNJ2BP synaptojanin 2 binding protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM246 transmembrane protein 246
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAIP TRAF interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN5 tetraspanin 5
TXLNG taxilin gamma
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UPB1 ureidopropionase, beta
VNN2 vanin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WASF3 WAS protein family, member 3
WDR62 WD repeat domain 62
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF268 zinc finger protein 268
ZNF354A zinc finger protein 354A
ZNF528 zinc finger protein 528
ZNF74 zinc finger protein 74