| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the propylthiouracil-2837 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ALS2CL | ALS2 C-terminal like |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATM | ATM serine/threonine kinase |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CCDC68 | coiled-coil domain containing 68 |
| CD22 | CD22 molecule |
| CDC25C | cell division cycle 25C |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CLPS | colipase, pancreatic |
| COL2A1 | collagen, type II, alpha 1 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DLX2 | distal-less homeobox 2 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM49B | family with sequence similarity 49, member B |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FKRP | fukutin related protein |
| FRMD1 | FERM domain containing 1 |
| GAST | gastrin |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| HFE | hemochromatosis |
| HHAT | hedgehog acyltransferase |
| HIST1H4A | histone cluster 1, H4a |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IFT27 | intraflagellar transport 27 |
| ING2 | inhibitor of growth family, member 2 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRS2 | insulin receptor substrate 2 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MLXIP | MLX interacting protein |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NME5 | NME/NM23 family member 5 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRDX2 | peroxiredoxin 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RANBP1 | RAN binding protein 1 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RPL35A | ribosomal protein L35a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAGD | Ras-related GTP binding D |
| RUNX1 | runt-related transcription factor 1 |
| SEC24D | SEC24 family member D |
| SH2D3A | SH2 domain containing 3A |
| SH2D3C | SH2 domain containing 3C |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| STMN1 | stathmin 1 |
| TCP10 | t-complex 10 |
| TDRD12 | tudor domain containing 12 |
| TENM4 | teneurin transmembrane protein 4 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRO | trophinin |
| TWF1 | twinfilin actin binding protein 1 |
| UBQLN4 | ubiquilin 4 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF224 | zinc finger protein 224 |
| ZNF287 | zinc finger protein 287 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ACTN4 | actinin, alpha 4 |
| ATG2A | autophagy related 2A |
| ATG9A | autophagy related 9A |
| AVEN | apoptosis, caspase activation inhibitor |
| B3GNT1 | |
| BBS1 | Bardet-Biedl syndrome 1 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CBR4 | carbonyl reductase 4 |
| CCDC186 | coiled-coil domain containing 186 |
| CCNO | cyclin O |
| CCNT1 | cyclin T1 |
| CHKB | choline kinase beta |
| CIC | capicua transcriptional repressor |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COBL | cordon-bleu WH2 repeat protein |
| COL4A5 | collagen, type IV, alpha 5 |
| CORT | cortistatin |
| CTSK | cathepsin K |
| CUEDC2 | CUE domain containing 2 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DENND4A | DENN/MADD domain containing 4A |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DVL1 | dishevelled segment polarity protein 1 |
| EPS8L2 | EPS8-like 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GK3P | glycerol kinase 3 pseudogene |
| GLCE | glucuronic acid epimerase |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPATCH3 | G patch domain containing 3 |
| GYS1 | glycogen synthase 1 (muscle) |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2BC | histone cluster 1, H2bc |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIF20B | kinesin family member 20B |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LYRM9 | LYR motif containing 9 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MEIS1 | Meis homeobox 1 |
| METTL16 | methyltransferase like 16 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MID1IP1 | MID1 interacting protein 1 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MYL5 | myosin, light chain 5, regulatory |
| NLK | nemo-like kinase |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OLFML3 | olfactomedin-like 3 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PADI2 | peptidyl arginine deiminase, type II |
| PC | pyruvate carboxylase |
| PRPH | peripherin |
| PTDSS2 | phosphatidylserine synthase 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SIRT2 | sirtuin 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD7 | SMAD family member 7 |
| SNUPN | snurportin 1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA2L | spermatogenesis associated 2-like |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPRYD7 | SPRY domain containing 7 |
| SREK1IP1 | SREK1-interacting protein 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STRN | striatin, calmodulin binding protein |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TMEM115 | transmembrane protein 115 |
| TMEM120B | transmembrane protein 120B |
| TRABD | TraB domain containing |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC33 | tetratricopeptide repeat domain 33 |
| WDR4 | WD repeat domain 4 |
| XYLT2 | xylosyltransferase II |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF250 | zinc finger protein 250 |
| ZNF35 | zinc finger protein 35 |
| ZNF571 | zinc finger protein 571 |
