propylthiouracil-4076 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the propylthiouracil-4076 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AICDA activation-induced cytidine deaminase
AKAP6 A kinase (PRKA) anchor protein 6
ANAPC13 anaphase promoting complex subunit 13
ANGPT1 angiopoietin 1
ANGPT4 angiopoietin 4
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
AR androgen receptor
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
CA9 carbonic anhydrase IX
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCR1 chemokine (C-C motif) receptor 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYTH3 cytohesin 3
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF11 DDB1 and CUL4 associated factor 11
DGCR14 DiGeorge syndrome critical region gene 14
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EDIL3 EGF-like repeats and discoidin I-like domains 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESRRG estrogen-related receptor gamma
FAM76A family with sequence similarity 76, member A
FUBP1 far upstream element (FUSE) binding protein 1
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GPR161 G protein-coupled receptor 161
GPR17 G protein-coupled receptor 17
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HHIPL2 HHIP-like 2
HIST1H2BB histone cluster 1, H2bb
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXC11 homeobox C11
HSF1 heat shock transcription factor 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1RN interleukin 1 receptor antagonist
KLK7 kallikrein-related peptidase 7
MAGEA5 melanoma antigen family A5
MAPK11 mitogen-activated protein kinase 11
METTL7A methyltransferase like 7A
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MKL1 megakaryoblastic leukemia (translocation) 1
MPZ myelin protein zero
MTRF1L mitochondrial translational release factor 1-like
MYO9B myosin IXB
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NPTX2 neuronal pentraxin II
NRCAM neuronal cell adhesion molecule
NXPH3 neurexophilin 3
PAWR PRKC, apoptosis, WT1, regulator
PCDH1 protocadherin 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PPARD peroxisome proliferator-activated receptor delta
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRB3 proline-rich protein BstNI subfamily 3
PRLH prolactin releasing hormone
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRU protein tyrosine phosphatase, receptor type, U
RAP1GAP RAP1 GTPase activating protein
RIMS3 regulating synaptic membrane exocytosis 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RNF43 ring finger protein 43
RPH3A rabphilin 3A
SAFB scaffold attachment factor B
SARM1 sterile alpha and TIR motif containing 1
SFTPB surfactant protein B
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A14 solute carrier family 22, member 14
SLMO1 slowmo homolog 1 (Drosophila)
SMAD5-AS1 SMAD5 antisense RNA 1
SMPX small muscle protein, X-linked
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOS2 son of sevenless homolog 2 (Drosophila)
SPIDR scaffolding protein involved in DNA repair
SPRED2 sprouty-related, EVH1 domain containing 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYT11 synaptotagmin XI
TBX1 T-box 1
TCF3 transcription factor 3
TCP10 t-complex 10
THOP1 thimet oligopeptidase 1
TMEM176A transmembrane protein 176A
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TPSAB1 tryptase alpha/beta 1
TRIM29 tripartite motif containing 29
TSC2 tuberous sclerosis 2
UPK3B uroplakin 3B
WSB1 WD repeat and SOCS box containing 1
ZNF334 zinc finger protein 334
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAM2 ADAM metallopeptidase domain 2
ADAM23 ADAM metallopeptidase domain 23
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASTN1 astrotactin 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BIK BCL2-interacting killer (apoptosis-inducing)
BMP15 bone morphogenetic protein 15
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF105 chromosome 14 open reading frame 105
C1ORF105 chromosome 1 open reading frame 105
C3AR1 complement component 3a receptor 1
C7ORF69 chromosome 7 open reading frame 69
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CFAP45 cilia and flagella associated protein 45
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNN1 calponin 1, basic, smooth muscle
CPNE7 copine VII
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DAGLA diacylglycerol lipase, alpha
DEPTOR DEP domain containing MTOR-interacting protein
DMTN dematin actin binding protein
EXD3 exonuclease 3'-5' domain containing 3
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM120C family with sequence similarity 120C
FBXO31 F-box protein 31
GRTP1 growth hormone regulated TBC protein 1
HIRA histone cell cycle regulator
HIST1H3C histone cluster 1, H3c
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IFT54 intraflagellar transport 54
IL17RB interleukin 17 receptor B
IQSEC2 IQ motif and Sec7 domain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KIAA0319L KIAA0319-like
KLF13 Kruppel-like factor 13
LIME1 Lck interacting transmembrane adaptor 1
LIMS2 LIM and senescent cell antigen-like domains 2
LY6D lymphocyte antigen 6 complex, locus D
MCTP1 multiple C2 domains, transmembrane 1
MGP matrix Gla protein
MMRN2 multimerin 2
MNT MAX network transcriptional repressor
NACA2 nascent polypeptide-associated complex alpha subunit 2
NPFFR1 neuropeptide FF receptor 1
NPVF neuropeptide VF precursor
NTSR1 neurotensin receptor 1 (high affinity)
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBP2 oxysterol binding protein 2
OSR2 odd-skipped related transciption factor 2
PCDHA5 protocadherin alpha 5
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLAG1 pleiomorphic adenoma gene 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS22 protease, serine, 22
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAPSN receptor-associated protein of the synapse
RIBC2 RIB43A domain with coiled-coils 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPGRIP1L RPGRIP1-like
RPP25 ribonuclease P/MRP 25kDa subunit
SAMD9 sterile alpha motif domain containing 9
SIRT6 sirtuin 6
SLC16A6 solute carrier family 16, member 6
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SPTBN2 spectrin, beta, non-erythrocytic 2
TAGLN transgelin
TAOK1 TAO kinase 1
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THSD4 thrombospondin, type I, domain containing 4
TIGD6 tigger transposable element derived 6
TPCN1 two pore segment channel 1
TRIM9 tripartite motif containing 9
TUBA3D tubulin, alpha 3d
TUBA4B tubulin, alpha 4b
ZNF446 zinc finger protein 446
ZNF549 zinc finger protein 549
ZNF749 zinc finger protein 749