| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the proscillaridin-7340 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AFF4 | AF4/FMR2 family, member 4 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AMOTL2 | angiomotin like 2 |
| ATF3 | activating transcription factor 3 |
| AVPI1 | arginine vasopressin-induced 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCDC186 | coiled-coil domain containing 186 |
| CCNL1 | cyclin L1 |
| CLDN1 | claudin 1 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EEA1 | early endosome antigen 1 |
| EED | embryonic ectoderm development |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EPHA2 | EPH receptor A2 |
| FAM46A | family with sequence similarity 46, member A |
| FASTKD2 | FAST kinase domains 2 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HCFC2 | host cell factor C2 |
| HIC2 | hypermethylated in cancer 2 |
| HIST2H2BE | histone cluster 2, H2be |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IL6 | interleukin 6 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLF6 | Kruppel-like factor 6 |
| KLHL20 | kelch-like family member 20 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MCL1 | myeloid cell leukemia 1 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OVOL1 | ovo-like zinc finger 1 |
| PCDH9 | protocadherin 9 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POU2F1 | POU class 2 homeobox 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPC1 | paraspeckle component 1 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM5 | RNA binding motif protein 5 |
| SERTAD3 | SERTA domain containing 3 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIK1 | salt-inducible kinase 1 |
| SKIL | SKI-like proto-oncogene |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| STK17B | serine/threonine kinase 17b |
| STX3 | syntaxin 3 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TGFB2 | transforming growth factor, beta 2 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TXNIP | thioredoxin interacting protein |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| YTHDC1 | YTH domain containing 1 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZFX | zinc finger protein, X-linked |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF654 | zinc finger protein 654 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADORA2B | adenosine A2b receptor |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANKRD46 | ankyrin repeat domain 46 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BBX | bobby sox homolog (Drosophila) |
| CBX7 | chromobox homolog 7 |
| CCDC15 | coiled-coil domain containing 15 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CXORF40A | chromosome X open reading frame 40A |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| EAF2 | ELL associated factor 2 |
| EGR3 | early growth response 3 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FANCF | Fanconi anemia, complementation group F |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FHOD1 | formin homology 2 domain containing 1 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GPR19 | G protein-coupled receptor 19 |
| GTF2E1 | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| HIRIP3 | HIRA interacting protein 3 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IFRD1 | interferon-related developmental regulator 1 |
| IL4R | interleukin 4 receptor |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0125 | KIAA0125 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRRC61 | leucine rich repeat containing 61 |
| MINA | MYC induced nuclear antigen |
| MKKS | McKusick-Kaufman syndrome |
| MNS1 | meiosis-specific nuclear structural 1 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MRPS31 | mitochondrial ribosomal protein S31 |
| NELFE | negative elongation factor complex member E |
| NOL8 | nucleolar protein 8 |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| POLI | polymerase (DNA directed) iota |
| POLR3B | polymerase (RNA) III (DNA directed) polypeptide B |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| RUFY2 | RUN and FYVE domain containing 2 |
| RWDD2A | RWD domain containing 2A |
| SALL2 | spalt-like transcription factor 2 |
| SAV1 | salvador family WW domain containing protein 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SYT17 | synaptotagmin XVII |
| TBC1D31 | TBC1 domain family, member 31 |
| TFB1M | transcription factor B1, mitochondrial |
| THAP7 | THAP domain containing 7 |
| TMEM177 | transmembrane protein 177 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TRIM27 | tripartite motif containing 27 |
| TRIM45 | tripartite motif containing 45 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| WDR3 | WD repeat domain 3 |
| WDR5B | WD repeat domain 5B |
| XBP1 | X-box binding protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF133 | zinc finger protein 133 |
| ZNF184 | zinc finger protein 184 |
| ZNF23 | zinc finger protein 23 |
| ZNF239 | zinc finger protein 239 |
| ZNF248 | zinc finger protein 248 |
| ZNF302 | zinc finger protein 302 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
| ZXDC | ZXD family zinc finger C |
