prostaglandin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Naturally occurring compounds derived from the parent C20 acid, prostanoic acid. (Chemical Entities of Biological Interest Ontology, CHEBI_26333)
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Genes

153 genes co-occuring with the biological term prostaglandin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACLY ATP citrate lyase
ADIPOQ adiponectin, C1Q and collagen domain containing
AHR aryl hydrocarbon receptor
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5 arachidonate 5-lipoxygenase
ANXA1 annexin A1
APP amyloid beta (A4) precursor protein
AR androgen receptor
AREG amphiregulin
ARG1 arginase 1
BANP BTG3 associated nuclear protein
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BTC betacellulin
CAMP cathelicidin antimicrobial peptide
CBR1 carbonyl reductase 1
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD83 CD83 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLDN4 claudin 4
COL2A1 collagen, type II, alpha 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EREG epiregulin
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FOXF1 forkhead box F1
GHSR growth hormone secretagogue receptor
HAND2 heart and neural crest derivatives expressed 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPGDS hematopoietic prostaglandin D synthase
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSF1 heat shock transcription factor 1
IDO1 indoleamine 2,3-dioxygenase 1
IL10 interleukin 10
IL11 interleukin 11
IL13 interleukin 13
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK1 Janus kinase 1
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KLF11 Kruppel-like factor 11
KNG1 kininogen 1
LEP leptin
LPA lipoprotein, Lp(a)
LYPLA2 lysophospholipase II
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK9 mitogen-activated protein kinase 9
MAPKAP1 mitogen-activated protein kinase associated protein 1
MIR146A microRNA 146a
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MNX1 motor neuron and pancreas homeobox 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NCF1 neutrophil cytosolic factor 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PLA2G12A phospholipase A2, group XIIA
PLA2G2E phospholipase A2, group IIE
PLA2G3 phospholipase A2, group III
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
POMC proopiomelanocortin
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGES prostaglandin E synthase
PTGES2 prostaglandin E synthase 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGFR prostaglandin F receptor (FP)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PVALB parvalbumin
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARB retinoic acid receptor, beta
RASGRP4 RAS guanyl releasing protein 4
RCAN1 regulator of calcineurin 1
RGS4 regulator of G-protein signaling 4
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A8 S100 calcium binding protein A8
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFTPA1 surfactant protein A1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOCS3 suppressor of cytokine signaling 3
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBXA2R thromboxane A2 receptor
TBXAS1 thromboxane A synthase 1 (platelet)
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TREM1 triggering receptor expressed on myeloid cells 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
ZFP36 ZFP36 ring finger protein