proteases Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

194 genes co-occuring with the biological term proteases in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
A2ML1 alpha-2-macroglobulin-like 1
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACE angiotensin I converting enzyme
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AFG3L2 AFG3-like AAA ATPase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AMBRA1 autophagy/beclin-1 regulator 1
ANG angiogenin, ribonuclease, RNase A family, 5
APLP2 amyloid beta (A4) precursor-like protein 2
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ASPRV1 aspartic peptidase, retroviral-like 1
ASTL astacin-like metallo-endopeptidase (M12 family)
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATXN3 ataxin 3
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
BDNF brain-derived neurotrophic factor
BLMH bleomycin hydrolase
C1QA complement component 1, q subcomponent, A chain
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CHEK1 checkpoint kinase 1
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
COL25A1 collagen, type XXV, alpha 1
COLEC11 collectin sub-family member 11
CPA1 carboxypeptidase A1 (pancreatic)
CRH corticotropin releasing hormone
CRYAA crystallin, alpha A
CST1 cystatin SN
CST3 cystatin C
CSTA cystatin A (stefin A)
CTSB cathepsin B
CTSC cathepsin C
CTSD cathepsin D
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CTSZ cathepsin Z
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DSC1 desmocollin 1
DSG1 desmoglein 1
DSG2 desmoglein 2
EDN1 endothelin 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ELANE elastase, neutrophil expressed
F10 coagulation factor X
F11 coagulation factor XI
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F9 coagulation factor IX
FASLG Fas ligand (TNF superfamily, member 6)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FGF23 fibroblast growth factor 23
FURIN furin (paired basic amino acid cleaving enzyme)
FUS FUS RNA binding protein
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HM13 histocompatibility (minor) 13
HMGB1 high mobility group box 1
HPN hepsin
HPSE heparanase
HPX hemopexin
HTRA2 HtrA serine peptidase 2
HTRA4 HtrA serine peptidase 4
HTT huntingtin
IFNG interferon, gamma
IGFBP3 insulin-like growth factor binding protein 3
IGHA1 immunoglobulin heavy constant alpha 1
IL13 interleukin 13
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1R2 interleukin 1 receptor, type II
IL25 interleukin 25
IL4 interleukin 4
IL5 interleukin 5
IL6R interleukin 6 receptor
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA9 integrin, alpha 9
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
ITGB6 integrin, beta 6
JPH1 junctophilin 1
JPH2 junctophilin 2
KLK5 kallikrein-related peptidase 5
KLK7 kallikrein-related peptidase 7
LGMN legumain
LMAN1 lectin, mannose-binding, 1
LONP1 lon peptidase 1, mitochondrial
MAGEA3 melanoma antigen family A3
MAPT microtubule-associated protein tau
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MUC2 mucin 2, oligomeric mucus/gel-forming
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRD1 nardilysin (N-arginine dibasic convertase)
OMA1 OMA1 zinc metallopeptidase
OPA1 optic atrophy 1 (autosomal dominant)
PADI4 peptidyl arginine deiminase, type IV
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PLAU plasminogen activator, urokinase
PLG plasminogen
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPBPP1 pro-platelet basic protein pseudogene 1
PRKCZ protein kinase C, zeta
PRSS27 protease, serine 27
PRSS3 protease, serine, 3
PRSS50 protease, serine, 50
PSAP prosaposin
PSENEN presenilin enhancer gamma secretase subunit
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RHOA ras homolog family member A
RNASE7 ribonuclease, RNase A family, 7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SENP1 SUMO1/sentrin specific peptidase 1
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SENP5 SUMO1/sentrin specific peptidase 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHBG sex hormone-binding globulin
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
SPPL2A signal peptide peptidase like 2A
SPPL3 signal peptide peptidase like 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUMO1 small ubiquitin-like modifier 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR9 toll-like receptor 9
TMPRSS11E transmembrane protease, serine 11E
TMPRSS13 transmembrane protease, serine 13
TMPRSS2 transmembrane protease, serine 2
TMPRSS4 transmembrane protease, serine 4
TNF tumor necrosis factor
TSLP thymic stromal lymphopoietin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
VASP vasodilator-stimulated phosphoprotein
VWF von Willebrand factor