proteasomal protein catabolic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. (Gene Ontology, GO_0010498)
External Link http://amigo.geneontology.org/amigo/term/GO_0010498
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Genes

221 genes participating in the proteasomal protein catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADRM1 adhesion regulating molecule 1
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AMBRA1 autophagy/beclin-1 regulator 1
ANKRD9 ankyrin repeat domain 9
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARMC8 armadillo repeat containing 8
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASB2 ankyrin repeat and SOCS box containing 2
ATE1 arginyltransferase 1
ATF6 activating transcription factor 6
ATXN3 ataxin 3
AXIN1 axin 1
AXIN2 axin 2
BAG6 BCL2-associated athanogene 6
BFAR bifunctional apoptosis regulator
BIRC2 baculoviral IAP repeat containing 2
BRSK2 BR serine/threonine kinase 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCDC47 coiled-coil domain containing 47
CDC34 cell division cycle 34
CLOCK clock circadian regulator
COP1 COP1 E3 ubiquitin ligase
CRBN cereblon
CSNK1A1 casein kinase 1, alpha 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
CUL3 cullin 3
CUL4A cullin 4A
CUL4B cullin 4B
DCAF11 DDB1 and CUL4 associated factor 11
DDB1 damage-specific DNA binding protein 1, 127kDa
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DDIT3 DNA-damage-inducible transcript 3
DERL1 derlin 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DTX4 deltex 4, E3 ubiquitin ligase
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERCC8 excision repair cross-complementation group 8
ERLEC1 endoplasmic reticulum lectin 1
FAF1 Fas (TNFRSF6) associated factor 1
FBXL17 F-box and leucine-rich repeat protein 17
FBXL19 F-box and leucine-rich repeat protein 19
FBXL22 F-box and leucine-rich repeat protein 22
FBXO44 F-box protein 44
FBXO45 F-box protein 45
FBXO7 F-box protein 7
FBXO9 F-box protein 9
FBXW11 F-box and WD repeat domain containing 11
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FEM1B fem-1 homolog b (C. elegans)
FEM1C fem-1 homolog c (C. elegans)
GID4 GID complex subunit 4
GID8 GID complex subunit 8
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
IFI27 interferon, alpha-inducible protein 27
ITCH itchy E3 ubiquitin protein ligase
KAT5 K(lysine) acetyltransferase 5
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KCTD10 potassium channel tetramerization domain containing 10
KCTD13 potassium channel tetramerization domain containing 13
KCTD17 potassium channel tetramerization domain containing 17
KCTD2 potassium channel tetramerization domain containing 2
KCTD5 potassium channel tetramerization domain containing 5
KIF14 kinesin family member 14
KLHDC2 kelch domain containing 2
KLHDC3 kelch domain containing 3
KLHL20 kelch-like family member 20
KLHL22 kelch-like family member 22
KLHL42 kelch-like family member 42
LOC122513141 ring finger protein-like
MAEA macrophage erythroblast attacher
MARCHF6 membrane associated ring-CH-type finger 6
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTA1 metastasis associated 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFE2L2 nuclear factor, erythroid 2-like 2
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NHLRC3 NHL repeat containing 3
NR1D1 nuclear receptor subfamily 1, group D, member 1
NSFL1C NSFL1 (p97) cofactor (p47)
PARK2 parkin RBR E3 ubiquitin protein ligase
PCBP2 poly(rC) binding protein 2
PCNP PEST proteolytic signal containing nuclear protein
PELI1 pellino E3 ubiquitin protein ligase 1
PEX10 peroxisomal biogenesis factor 10
PEX12 peroxisomal biogenesis factor 12
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLAA phospholipase A2-activating protein
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRAME preferentially expressed antigen in melanoma
PRAMEF6 PRAME family member 6
PRAMEF9 PRAME family member 9
PRPF19 pre-mRNA processing factor 19
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSME4 proteasome (prosome, macropain) activator subunit 4
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCAN3 RCAN family member 3
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RHBDD1 rhomboid domain containing 1
RHOBTB3 Rho-related BTB domain containing 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF122 ring finger protein 122
RNF126 ring finger protein 126
RNF139 ring finger protein 139
RNF185 ring finger protein 185
RNF186 ring finger protein 186
RNF187 ring finger protein 187
RNF216 ring finger protein 216
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans)
SH3BGRL SH3 domain binding glutamate-rich protein like
SHARPIN SHANK-associated RH domain interactor
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIAH3 siah E3 ubiquitin protein ligase family member 3
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOCS6 suppressor of cytokine signaling 6
SPOP speckle-type POZ protein
SPOPL speckle-type POZ protein-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBX21 T-box 21
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM13 tripartite motif containing 13
TRIM2 tripartite motif containing 2
TRIM21 tripartite motif containing 21
TRIM3 tripartite motif containing 3
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TRIM9 tripartite motif containing 9
TRIP12 thyroid hormone receptor interactor 12
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2K ubiquitin-conjugating enzyme E2K
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE3D ubiquitin protein ligase E3D
UBE4B ubiquitination factor E4B
UBXN1 UBX domain protein 1
UBXN11 UBX domain protein 11
UBXN2A UBX domain protein 2A
UBXN2B UBX domain protein 2B
UBXN6 UBX domain protein 6
UBXN7 UBX domain protein 7
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USP44 ubiquitin specific peptidase 44
VCP valosin containing protein
WDR26 WD repeat domain 26
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XBP1 X-box binding protein 1
ZFAND2A zinc finger, AN1-type domain 2A
ZFAND2B zinc finger, AN1-type domain 2B
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase
ZSWIM8 zinc finger, SWIM-type containing 8