protein K11-linked ubiquitination Gene Set
Dataset
GO Biological Process Annotations 2023
Category
structural or functional annotations
Type
biological process
Description
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains. (Gene Ontology , GO_0070979 )
External Link
http://amigo.geneontology.org/amigo/term/GO_0070979
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Genes
30 genes participating in the protein K11-linked ubiquitination biological process from the curated GO Biological Process Annotations 2023 dataset.
Symbol
Name
ANAPC1
anaphase promoting complex subunit 1
ANAPC10
anaphase promoting complex subunit 10
ANAPC11
anaphase promoting complex subunit 11
ANAPC13
anaphase promoting complex subunit 13
ANAPC2
anaphase promoting complex subunit 2
ANAPC4
anaphase promoting complex subunit 4
ANAPC5
anaphase promoting complex subunit 5
ANAPC7
anaphase promoting complex subunit 7
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
CDC16
cell division cycle 16
CDC23
cell division cycle 23
CDC26
cell division cycle 26
CDC27
cell division cycle 27
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
PARK2
parkin RBR E3 ubiquitin protein ligase
RNF26
ring finger protein 26
RNF4
ring finger protein 4
UBE2A
ubiquitin-conjugating enzyme E2A
UBE2B
ubiquitin-conjugating enzyme E2B
UBE2C
ubiquitin-conjugating enzyme E2C
UBE2D3
ubiquitin-conjugating enzyme E2D 3
UBE2D4
ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E2
ubiquitin-conjugating enzyme E2E 2
UBE2E3
ubiquitin-conjugating enzyme E2E 3
UBE2H
ubiquitin-conjugating enzyme E2H
UBE2L3
ubiquitin-conjugating enzyme E2L 3
UBE2L5P
ubiquitin-conjugating enzyme E2L 5 (pseudogene)
UBE2S
ubiquitin-conjugating enzyme E2S
UBE2T
ubiquitin-conjugating enzyme E2T
UBE2W
ubiquitin-conjugating enzyme E2W (putative)