protein K48-linked ubiquitination Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation. (Gene Ontology, GO_0070936)
External Link http://amigo.geneontology.org/amigo/term/GO_0070936
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Genes

71 genes participating in the protein K48-linked ubiquitination biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
BFAR bifunctional apoptosis regulator
CDC34 cell division cycle 34
CUL1 cullin 1
CUL3 cullin 3
DTX3L deltex 3 like, E3 ubiquitin ligase
FBXO38 F-box protein 38
FBXO45 F-box protein 45
FBXO7 F-box protein 7
FBXO9 F-box protein 9
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
IFI27 interferon, alpha-inducible protein 27
ITCH itchy E3 ubiquitin protein ligase
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KLHL3 kelch-like family member 3
MARCHF6 membrane associated ring-CH-type finger 6
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NT5C2 5'-nucleotidase, cytosolic II
PARK2 parkin RBR E3 ubiquitin protein ligase
PELI1 pellino E3 ubiquitin protein ligase 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RNF115 ring finger protein 115
RNF126 ring finger protein 126
RNF146 ring finger protein 146
RNF152 ring finger protein 152
RNF187 ring finger protein 187
RNF216 ring finger protein 216
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIM25 tripartite motif containing 25
TRIM31 tripartite motif containing 31
TRIM32 tripartite motif containing 32
TRIM45 tripartite motif containing 45
TRIM6 tripartite motif containing 6
TRIM65 tripartite motif containing 65
TTC3 tetratricopeptide repeat domain 3
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2K ubiquitin-conjugating enzyme E2K
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2T ubiquitin-conjugating enzyme E2T
UBE3A ubiquitin protein ligase E3A
UBE3C ubiquitin protein ligase E3C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase