protein K63-linked deubiquitination Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein. (Gene Ontology, GO_0070536)
External Link http://amigo.geneontology.org/amigo/term/GO:0070536
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Genes

24 genes participating in the protein K63-linked deubiquitination biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABRAXAS2 abraxas 2, BRISC complex subunit
ATXN3 ataxin 3
BABAM2 BRISC and BRCA1 A complex member 2
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
CYLD cylindromatosis (turban tumor syndrome)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD1 OTU deubiquitinase 1
OTUD4 OTU deubiquitinase 4
OTUD5 OTU deubiquitinase 5
OTUD7B OTU deubiquitinase 7B
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SPATA2 spermatogenesis associated 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP20 ubiquitin specific peptidase 20
USP25 ubiquitin specific peptidase 25
USP27X ubiquitin specific peptidase 27, X-linked
USP33 ubiquitin specific peptidase 33
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
YOD1 YOD1 deubiquitinase
ZRANB1 zinc finger, RAN-binding domain containing 1