protein K63-linked ubiquitination Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair. (Gene Ontology, GO_0070534)
External Link http://amigo.geneontology.org/amigo/term/GO:0070534
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Genes

59 genes participating in the protein K63-linked ubiquitination biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKTIP AKT interacting protein
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARRDC4 arrestin domain containing 4
ARTN artemin
BFAR bifunctional apoptosis regulator
CDKN2A cyclin-dependent kinase inhibitor 2A
ITCH itchy E3 ubiquitin protein ligase
KCMF1 potassium channel modulatory factor 1
LOC122513141 ring finger protein-like
MAGEL2 melanoma antigen family L2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
PELI1 pellino E3 ubiquitin protein ligase 1
PELI3 pellino E3 ubiquitin protein ligase family member 3
PRKN parkin RBR E3 ubiquitin protein ligase
PRPF19 pre-mRNA processing factor 19
RNF115 ring finger protein 115
RNF126 ring finger protein 126
RNF135 ring finger protein 135
RNF152 ring finger protein 152
RNF167 ring finger protein 167
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF186 ring finger protein 186
RNF213 ring finger protein 213
RNF39 ring finger protein 39
RNF4 ring finger protein 4
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TANK TRAF family member-associated NFKB activator
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM27 tripartite motif containing 27
TRIM3 tripartite motif containing 3
TRIM31 tripartite motif containing 31
TRIM32 tripartite motif containing 32
TRIM5 tripartite motif containing 5
TRIM56 tripartite motif containing 56
TRIM65 tripartite motif containing 65
TRIM8 tripartite motif containing 8
UBE2B ubiquitin-conjugating enzyme E2B
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2N ubiquitin-conjugating enzyme E2N
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2O ubiquitin-conjugating enzyme E2O
UBE2S ubiquitin-conjugating enzyme E2S
UBE2T ubiquitin-conjugating enzyme E2T
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UXT ubiquitously-expressed, prefoldin-like chaperone
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFP91 ZFP91 zinc finger protein
ZNF598 zinc finger protein 598