protein catabolic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. (Gene Ontology, GO_0030163)
External Link http://amigo.geneontology.org/amigo/term/GO_0030163
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Genes

103 genes participating in the protein catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AFG1L AFG1 like ATPase
APOE apolipoprotein E
ATE1 arginyltransferase 1
BAG6 BCL2-associated athanogene 6
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAPN2 calpain 2, (m/II) large subunit
CAPN3 calpain 3, (p94)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEL carboxyl ester lipase
CELA2A chymotrypsin-like elastase family, member 2A
CHEK2 checkpoint kinase 2
CLN5 ceroid-lipofuscinosis, neuronal 5
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CPA2 carboxypeptidase A2 (pancreatic)
CTRL chymotrypsin-like
CTSB cathepsin B
CTSC cathepsin C
CTSD cathepsin D
CTSF cathepsin F
CTSH cathepsin H
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
CTSW cathepsin W
CTSZ cathepsin Z
CUL4B cullin 4B
DAB2IP DAB2 interacting protein
DDB1 damage-specific DNA binding protein 1, 127kDa
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DENND3 DENN/MADD domain containing 3
DTX4 deltex 4, E3 ubiquitin ligase
ELANE elastase, neutrophil expressed
FBXO17 F-box protein 17
FBXO2 F-box protein 2
FBXO27 F-box protein 27
FBXO44 F-box protein 44
FBXO6 F-box protein 6
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA8 heat shock 70kDa protein 8
HTRA2 HtrA serine peptidase 2
IDE insulin-degrading enzyme
LAMP2 lysosomal-associated membrane protein 2
LGMN legumain
LONP1 lon peptidase 1, mitochondrial
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MAGEA2 melanoma antigen family A2
MAGEC2 melanoma antigen family C2
MALT1 MALT1 paracaspase
MANBA mannosidase, beta A, lysosomal
MARCHF6 membrane associated ring-CH-type finger 6
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
NEU2 sialidase 2 (cytosolic sialidase)
NEU4 sialidase 4
NGLY1 N-glycanase 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
OGA O-GlcNAcase
PARK2 parkin RBR E3 ubiquitin protein ligase
PCSK9 proprotein convertase subtilisin/kexin type 9
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPT1 palmitoyl-protein thioesterase 1
PRPF19 pre-mRNA processing factor 19
PRSS16 protease, serine, 16 (thymus)
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
RAB12 RAB12, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF123 ring finger protein 123
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RSPRY1 ring finger and SPRY domain containing 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIAH1 siah E3 ubiquitin protein ligase 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SOCS6 suppressor of cytokine signaling 6
SPATA18 spermatogenesis associated 18
SQSTM1 sequestosome 1
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TPP1 tripeptidyl peptidase I
TRIM21 tripartite motif containing 21
TRIM24 tripartite motif containing 24
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
UTP25 UTP25 small subunit processome component
VCP valosin containing protein
YME1L1 YME1-like 1 ATPase