protein destabilization Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. (Gene Ontology, GO_0031648)
External Link http://amigo.geneontology.org/amigo/term/GO:0031648
Similar Terms
Downloads & Tools

Genes

25 genes participating in the protein destabilization biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
BMP2 bone morphogenetic protein 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCDC88C coiled-coil domain containing 88C
CDC73 cell division cycle 73
CTSH cathepsin H
DERL1 derlin 1
FBXL3 F-box and leucine-rich repeat protein 3
FBXW11 F-box and WD repeat domain containing 11
GSN gelsolin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ISOC2 isochorismatase domain containing 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYLIP myosin regulatory light chain interacting protein
PEX2 peroxisomal biogenesis factor 2
PLK1 polo-like kinase 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RNF139 ring finger protein 139
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT1 sirtuin 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX17 SRY (sex determining region Y)-box 17
TRIM21 tripartite motif containing 21