protein destabilization Gene Set
Genes
37 genes participating in the protein destabilization biological process from the curated GO Biological Process Annotations 2023 dataset.
| Symbol |
Name |
|
BTRC
|
beta-transducin repeat containing E3 ubiquitin protein ligase
|
|
CAPN3
|
calpain 3, (p94)
|
|
CCDC88C
|
coiled-coil domain containing 88C
|
|
CDC73
|
cell division cycle 73
|
|
CREBBP
|
CREB binding protein
|
|
CTSH
|
cathepsin H
|
|
CUL3
|
cullin 3
|
|
DAZAP2
|
DAZ associated protein 2
|
|
DERL1
|
derlin 1
|
|
EP300
|
E1A binding protein p300
|
|
FBXL3
|
F-box and leucine-rich repeat protein 3
|
|
FBXW11
|
F-box and WD repeat domain containing 11
|
|
GGA3
|
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
|
|
GSN
|
gelsolin
|
|
HTT
|
huntingtin
|
|
IRGM
|
immunity-related GTPase family, M
|
|
ISOC2
|
isochorismatase domain containing 2
|
|
KDM8
|
lysine (K)-specific demethylase 8
|
|
MDM2
|
MDM2 proto-oncogene, E3 ubiquitin protein ligase
|
|
MUL1
|
mitochondrial E3 ubiquitin protein ligase 1
|
|
NR1D1
|
nuclear receptor subfamily 1, group D, member 1
|
|
PARK2
|
parkin RBR E3 ubiquitin protein ligase
|
|
PEX2
|
peroxisomal biogenesis factor 2
|
|
PLK1
|
polo-like kinase 1
|
|
PRNP
|
prion protein
|
|
PYHIN1
|
pyrin and HIN domain family, member 1
|
|
RAD23A
|
RAD23 homolog A (S. cerevisiae)
|
|
RNF139
|
ring finger protein 139
|
|
SERF1A
|
small EDRK-rich factor 1A (telomeric)
|
|
SERF2
|
small EDRK-rich factor 2
|
|
SIRT1
|
sirtuin 1
|
|
SIRT6
|
sirtuin 6
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
|
SOX17
|
SRY (sex determining region Y)-box 17
|
|
SUMO1
|
small ubiquitin-like modifier 1
|
|
TRIM21
|
tripartite motif containing 21
|
|
UTP25
|
UTP25 small subunit processome component
|
