protein deubiquitination Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The removal of one or more ubiquitin groups from a protein. (Gene Ontology, GO_0016579)
External Link http://amigo.geneontology.org/amigo/term/GO:0016579
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Genes

77 genes participating in the protein deubiquitination biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABRAXAS2 abraxas 2, BRISC complex subunit
ATXN3 ataxin 3
ATXN3L ataxin 3-like
BABAM2 BRISC and BRCA1 A complex member 2
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
CDK1 cyclin-dependent kinase 1
CYLD cylindromatosis (turban tumor syndrome)
JOSD1 Josephin domain containing 1
JOSD2 Josephin domain containing 2
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD1 OTU deubiquitinase 1
OTUD3 OTU deubiquitinase 3
OTUD4 OTU deubiquitinase 4
OTUD5 OTU deubiquitinase 5
OTUD6A OTU deubiquitinase 6A
OTUD6B OTU domain containing 6B
OTUD7A OTU deubiquitinase 7A
OTUD7B OTU deubiquitinase 7B
OTULIN OTU deubiquitinase with linear linkage specificity
OTULINL OTU deubiquitinase with linear linkage specificity like
PRKN parkin RBR E3 ubiquitin protein ligase
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
SENP8 SUMO/sentrin specific peptidase family member 8
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SPATA2 spermatogenesis associated 2
STAMBP STAM binding protein
STAMBPL1 STAM binding protein-like 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP1 ubiquitin specific peptidase 1
USP11 ubiquitin specific peptidase 11
USP12 ubiquitin specific peptidase 12
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP15 ubiquitin specific peptidase 15
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP17L24 ubiquitin specific peptidase 17-like family member 24
USP18 ubiquitin specific peptidase 18
USP19 ubiquitin specific peptidase 19
USP2 ubiquitin specific peptidase 2
USP20 ubiquitin specific peptidase 20
USP21 ubiquitin specific peptidase 21
USP22 ubiquitin specific peptidase 22
USP24 ubiquitin specific peptidase 24
USP25 ubiquitin specific peptidase 25
USP27X ubiquitin specific peptidase 27, X-linked
USP28 ubiquitin specific peptidase 28
USP29 ubiquitin specific peptidase 29
USP30 ubiquitin specific peptidase 30
USP32 ubiquitin specific peptidase 32
USP33 ubiquitin specific peptidase 33
USP34 ubiquitin specific peptidase 34
USP36 ubiquitin specific peptidase 36
USP37 ubiquitin specific peptidase 37
USP38 ubiquitin specific peptidase 38
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP42 ubiquitin specific peptidase 42
USP44 ubiquitin specific peptidase 44
USP45 ubiquitin specific peptidase 45
USP46 ubiquitin specific peptidase 46
USP47 ubiquitin specific peptidase 47
USP49 ubiquitin specific peptidase 49
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP50 ubiquitin specific peptidase 50
USP6 ubiquitin specific peptidase 6
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
USP9Y ubiquitin specific peptidase 9, Y-linked
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
YOD1 YOD1 deubiquitinase
ZC3H12A zinc finger CCCH-type containing 12A
ZRANB1 zinc finger, RAN-binding domain containing 1