protein heterodimerization activity Gene Set

Dataset GO Molecular Function Annotations 2023
Category structural or functional annotations
Type biological process
Description Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer. (Gene Ontology, GO_0046982)
External Link http://amigo.geneontology.org/amigo/term/GO:0046982
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Genes

191 genes performing the protein heterodimerization activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol Name
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ADCY8 adenylate cyclase 8 (brain)
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AOC3 amine oxidase, copper containing 3
APOA2 apolipoprotein A-II
ARNT aryl hydrocarbon receptor nuclear translocator
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
AURKA aurora kinase A
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BDKRB2 bradykinin receptor B2
BHLHA9 basic helix-loop-helix family, member a9
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BMP6 bone morphogenetic protein 6
BOK BCL2-related ovarian killer
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor
CD247 CD247 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CFHR5 complement factor H-related 5
CHUK conserved helix-loop-helix ubiquitous kinase
CREB3L3 cAMP responsive element binding protein 3-like 3
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DDIT3 DNA-damage-inducible transcript 3
DGKD diacylglycerol kinase, delta 130kDa
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
FBXO7 F-box protein 7
FMR1 fragile X mental retardation 1
FXR1 fragile X mental retardation, autosomal homolog 1
FXR2 fragile X mental retardation, autosomal homolog 2
FZD4 frizzled class receptor 4
FZD9 frizzled class receptor 9
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GCA grancalcin, EF-hand calcium binding protein
GPHA2 glycoprotein hormone alpha 2
GPHB5 glycoprotein hormone beta 5
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2A2 general transcription factor IIA, 2, 12kDa
HEXA hexosaminidase A (alpha polypeptide)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIP1 huntingtin interacting protein 1
HSF1 heat shock transcription factor 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL12A interleukin 12A
IL12B interleukin 12B
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KATNA1 katanin p60 (ATPase containing) subunit A 1
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT25 keratin 25, type I
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MCL1 myeloid cell leukemia 1
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
METTL3 methyltransferase like 3
MICU1 mitochondrial calcium uptake 1
MICU2 mitochondrial calcium uptake 2
MIGA1 mitoguardin 1
MIGA2 mitoguardin 2
MLX MLX, MAX dimerization protein
MLXIPL MLX interacting protein-like
MTTP microsomal triglyceride transfer protein
NAE1 NEDD8 activating enzyme E1 subunit 1
NEUROD1 neuronal differentiation 1
NEUROD2 neuronal differentiation 2
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPAS1 neuronal PAS domain protein 1
NPAS3 neuronal PAS domain protein 3
NPAS4 neuronal PAS domain protein 4
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
P4HB prolyl 4-hydroxylase, beta polypeptide
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PDCD6 programmed cell death 6
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PEF1 penta-EF-hand domain containing 1
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PHB prohibitin
PHB2 prohibitin 2
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRMT5 protein arginine methyltransferase 5
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
QTRT1 queuine tRNA-ribosyltransferase 1
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RAN RAN, member RAS oncogene family
RCC1 regulator of chromosome condensation 1
ROPN1B rhophilin associated tail protein 1B
RRAGA Ras-related GTP binding A
RRAGC Ras-related GTP binding C
RRAGD Ras-related GTP binding D
SAE1 SUMO1 activating enzyme subunit 1
SDCBP syndecan binding protein (syntenin)
SDCBP2 syndecan binding protein (syntenin) 2
SIM1 single-minded family bHLH transcription factor 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC51A solute carrier family 51, alpha subunit
SLC51B solute carrier family 51, beta subunit
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SNX1 sorting nexin 1
SNX2 sorting nexin 2
SOHLH1 spermatogenesis and oogenesis specific basic helix-loop-helix 1
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C
SRI sorcin
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TCF3 transcription factor 3
TCF4 transcription factor 4
TCOF1 Treacher Collins-Franceschetti syndrome 1
TENM1 teneurin transmembrane protein 1
TENM2 teneurin transmembrane protein 2
TENM3 teneurin transmembrane protein 3
TENM4 teneurin transmembrane protein 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TPM4 tropomyosin 4
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TUBB2B tubulin, beta 2B class IIb
UBA2 ubiquitin-like modifier activating enzyme 2
UBA3 ubiquitin-like modifier activating enzyme 3
USF1 upstream transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
XBP1 X-box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZBTB1 zinc finger and BTB domain containing 1
ZHX1 zinc fingers and homeoboxes 1
ZHX2 zinc fingers and homeoboxes 2
ZHX3 zinc fingers and homeoboxes 3