protein homooligomerization Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. (Gene Ontology, GO_0051260)
External Link http://amigo.geneontology.org/amigo/term/GO:0051260
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Genes

144 genes participating in the protein homooligomerization biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACOT13 acyl-CoA thioesterase 13
ADCY8 adenylate cyclase 8 (brain)
AKR1C1 aldo-keto reductase family 1, member C1
ALAD aminolevulinate dehydratase
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
APIP APAF1 interacting protein
APP amyloid beta (A4) precursor protein
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
AQP10 aquaporin 10
AQP11 aquaporin 11
AQP2 aquaporin 2 (collecting duct)
AQP4 aquaporin 4
AQP5 aquaporin 5
ARC activity-regulated cytoskeleton-associated protein
ATL2 atlastin GTPase 2
ATL3 atlastin GTPase 3
B2M beta-2-microglobulin
BASP1 brain abundant, membrane attached signal protein 1
BCL10 B-cell CLL/lymphoma 10
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEND3 BEN domain containing 3
BLM Bloom syndrome, RecQ helicase-like
CALHM1 calcium homeostasis modulator 1
CARD11 caspase recruitment domain family, member 11
CARD8 caspase recruitment domain family, member 8
CARD9 caspase recruitment domain family, member 9
CBR4 carbonyl reductase 4
CBY1 chibby homolog 1 (Drosophila)
CHMP2A charged multivesicular body protein 2A
CLYBL citrate lyase beta like
COMP cartilage oligomeric matrix protein
CRYZ crystallin, zeta (quinone reductase)
DEFA5 defensin, alpha 5, Paneth cell-specific
DELE1 DAP3 binding cell death enhancer 1
DNM1 dynamin 1
ECT2 epithelial cell transforming 2
EHD1 EH-domain containing 1
EHD3 EH-domain containing 3
EHD4 EH-domain containing 4
ELAVL1 ELAV like RNA binding protein 1
FUS FUS RNA binding protein
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GBP5 guanylate binding protein 5
GLRA3 glycine receptor, alpha 3
GLS2 glutaminase 2 (liver, mitochondrial)
GNMT glycine N-methyltransferase
GOLGA2 golgin A2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSDMD gasdermin D
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HLA-G major histocompatibility complex, class I, G
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
IAPP islet amyloid polypeptide
IKZF4 IKAROS family zinc finger 4 (Eos)
ITLN1 intelectin 1 (galactofuranose binding)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JMJD6 jumonji domain containing 6
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNT1 potassium channel, sodium activated subfamily T, member 1
KIF25 kinesin family member 25
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LOC112694756 uncharaterized LOC112694756
MAPT microtubule-associated protein tau
MAT1A methionine adenosyltransferase I, alpha
MCOLN1 mucolipin 1
MICU1 mitochondrial calcium uptake 1
MLKL mixed lineage kinase domain-like
MOSPD2 motile sperm domain containing 2
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NINJ1 ninjurin 1
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
OSBPL2 oxysterol binding protein-like 2
OTOL1 otolin 1
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCDHB16 protocadherin beta 16
PDCD6IP programmed cell death 6 interacting protein
PEG10 paternally expressed 10
PKD2L1 polycystic kidney disease 2-like 1
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLK polymerase (DNA directed) kappa
PRKD2 protein kinase D2
PRMT1 protein arginine methyltransferase 1
PRMT8 protein arginine methyltransferase 8
PXDN peroxidasin
PYCARD PYD and CARD domain containing
RBMX RNA binding motif protein, X-linked
RIPK2 receptor-interacting serine-threonine kinase 2
RNF112 ring finger protein 112
RNF135 ring finger protein 135
RSC1A1 regulatory solute carrier protein, family 1, member 1
RYR1 ryanodine receptor 1 (skeletal)
RYR3 ryanodine receptor 3
S100A9 S100 calcium binding protein A9
SAMD1 sterile alpha motif domain containing 1
SAMHD1 SAM domain and HD domain 1
SCARA5 scavenger receptor class A, member 5
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SOD2 superoxide dismutase 2, mitochondrial
SPAST spastin
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STEAP4 STEAP family member 4
SYCP1 synaptonemal complex protein 1
TDO2 tryptophan 2,3-dioxygenase
TGM2 transglutaminase 2
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
TIFA TRAF-interacting protein with forkhead-associated domain
TK1 thymidine kinase 1, soluble
TMEM120A transmembrane protein 120A
TMEM70 transmembrane protein 70
TP53BP1 tumor protein p53 binding protein 1
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV5 transient receptor potential cation channel, subfamily V, member 5
UPB1 ureidopropionase, beta
USP21 ubiquitin specific peptidase 21
VSIG2 V-set and immunoglobulin domain containing 2
VSTM5 V-set and transmembrane domain containing 5
ZBTB1 zinc finger and BTB domain containing 1
ZNF395 zinc finger protein 395
ZNF746 zinc finger protein 746