protein maturation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process leading to the attainment of the full functional capacity of a protein. (Gene Ontology, GO_0051604)
External Link http://amigo.geneontology.org/amigo/term/GO:0051604
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Genes

159 genes participating in the protein maturation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ACTMAP actin maturation protease
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM19 ADAM metallopeptidase domain 19
ADAM9 ADAM metallopeptidase domain 9
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AEBP1 AE binding protein 1
AFG3L2 AFG3-like AAA ATPase 2
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
ASPRV1 aspartic peptidase, retroviral-like 1
ATG4A autophagy related 4A, cysteine peptidase
ATG4B autophagy related 4B, cysteine peptidase
ATG4C autophagy related 4C, cysteine peptidase
ATG4D autophagy related 4D, cysteine peptidase
AURKAIP1 aurora kinase A interacting protein 1
AZU1 azurocidin 1
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
BMP1 bone morphogenetic protein 1
BOLA3 bolA family member 3
CALR calreticulin
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCS copper chaperone for superoxide dismutase
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
CIAO1 cytosolic iron-sulfur assembly component 1
CIAO2A cytosolic iron-sulfur assembly component 2A
CIAO2B cytosolic iron-sulfur assembly component 2B
CISD1 CDGSH iron sulfur domain 1
CISD3 CDGSH iron sulfur domain 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CMA1 chymase 1, mast cell
CPE carboxypeptidase E
CPM carboxypeptidase M
CPNE1 copine I
CPZ carboxypeptidase Z
CTSG cathepsin G
CTSS cathepsin S
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DHPS deoxyhypusine synthase
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DOHH deoxyhypusine hydroxylase/monooxygenase
DUOXA2 dual oxidase maturation factor 2
ECE1 endothelin converting enzyme 1
ECEL1 endothelin converting enzyme-like 1
EEF1AKMT4-ECE2 EEF1AKMT4-ECE2 readthrough
F12 coagulation factor XII (Hageman factor)
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FNTA farnesyltransferase, CAAX box, alpha
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GCSH glycine cleavage system protein H (aminomethyl carrier)
GLRX5 glutaredoxin 5
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
GZMK granzyme K (granzyme 3; tryptase II)
GZMM granzyme M (lymphocyte met-ase 1)
HOMER2 homer scaffolding protein 2
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ISCA1 iron-sulfur cluster assembly 1
ISCA2 iron-sulfur cluster assembly 2
KEL Kell blood group, metallo-endopeptidase
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KLK12 kallikrein-related peptidase 12
KLK13 kallikrein-related peptidase 13
KLK14 kallikrein-related peptidase 14
KLK15 kallikrein-related peptidase 15
KLK4 kallikrein-related peptidase 4
KLK5 kallikrein-related peptidase 5
KLK6 kallikrein-related peptidase 6
KLK8 kallikrein-related peptidase 8
KLK9 kallikrein-related peptidase 9
LGMN legumain
LIPT2 lipoyl(octanoyl) transferase 2 (putative)
LMF1 lipase maturation factor 1
LMF2 lipase maturation factor 2
LONP2 lon peptidase 2, peroxisomal
LTO1 LTO1 maturation factor of ABCE1
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METAP1 methionyl aminopeptidase 1
METAP2 methionyl aminopeptidase 2
MMEL1 membrane metallo-endopeptidase-like 1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NCSTN nicastrin
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NFU1 NFU1 iron-sulfur cluster scaffold
NLRP3 NLR family, pyrin domain containing 3
NNAT neuronatin
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PARL presenilin associated, rhomboid-like
PCSK4 proprotein convertase subtilisin/kexin type 4
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PGAP1 post-GPI attachment to proteins 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIKFYVE phosphoinositide kinase, FYVE finger containing
PITRM1 pitrilysin metallopeptidase 1
PRPH2 peripherin 2 (retinal degeneration, slow)
PRSS37 protease, serine, 37
PRSS57 protease, serine, 57
PRSS58 protease, serine, 58
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PTCH1 patched 1
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RNF123 ring finger protein 123
SDE2 SDE2 telomere maintenance homolog (S. pombe)
SRGN serglycin
TASP1 taspase, threonine aspartase, 1
TESC tescalcin
TLL1 tolloid-like 1
TLL2 tolloid-like 2
TMEM260 transmembrane protein 260
TMPRSS4 transmembrane protease, serine 4
TSPAN14 tetraspanin 14
TSPAN15 tetraspanin 15
TSPAN33 tetraspanin 33
TSPAN5 tetraspanin 5
TYSND1 trypsin domain containing 1
UBAC1 UBA domain containing 1
UFSP1 UFM1-specific peptidase 1 (non-functional)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
YAE1 YAE1 maturation factor of ABCE1
ZMPSTE24 zinc metallopeptidase STE24
ZNG1E Zn regulated GTPase metalloprotein activator 1E