protein polyubiquitination Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. (Gene Ontology, GO_0000209)
External Link http://amigo.geneontology.org/amigo/term/GO:0000209
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Genes

186 genes participating in the protein polyubiquitination biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC13 anaphase promoting complex subunit 13
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASB2 ankyrin repeat and SOCS box containing 2
AXIN1 axin 1
BARD1 BRCA1 associated RING domain 1
BCL2 B-cell CLL/lymphoma 2
BFAR bifunctional apoptosis regulator
BIRC2 baculoviral IAP repeat containing 2
BLMH bleomycin hydrolase
BRCA1 breast cancer 1, early onset
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CBFB core-binding factor, beta subunit
CDC16 cell division cycle 16
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC34 cell division cycle 34
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CUL3 cullin 3
DDB2 damage-specific DNA binding protein 2, 48kDa
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DZIP3 DAZ interacting zinc finger protein 3
ERCC8 excision repair cross-complementation group 8
FBXO22 F-box protein 22
FBXO4 F-box protein 4
FBXW11 F-box and WD repeat domain containing 11
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HDAC6 histone deacetylase 6
HLTF helicase-like transcription factor
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ITCH itchy E3 ubiquitin protein ligase
KLHL20 kelch-like family member 20
KLHL3 kelch-like family member 3
KLHL42 kelch-like family member 42
LNPEP leucyl/cystinyl aminopeptidase
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH5 membrane-associated ring finger (C3HC4) 5
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MKRN1 makorin ring finger protein 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NPEPPS aminopeptidase puromycin sensitive
PARK2 parkin RBR E3 ubiquitin protein ligase
PELI1 pellino E3 ubiquitin protein ligase 1
PELI3 pellino E3 ubiquitin protein ligase family member 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRPF19 pre-mRNA processing factor 19
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RC3H2 ring finger and CCCH-type domains 2
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RNF111 ring finger protein 111
RNF115 ring finger protein 115
RNF126 ring finger protein 126
RNF146 ring finger protein 146
RNF152 ring finger protein 152
RNF167 ring finger protein 167
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF180 ring finger protein 180
RNF187 ring finger protein 187
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF216 ring finger protein 216
RNF31 ring finger protein 31
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
RUSC1 RUN and SH3 domain containing 1
SASH1 SAM and SH3 domain containing 1
SHARPIN SHANK-associated RH domain interactor
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPP2 tripeptidyl peptidase II
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIM27 tripartite motif containing 27
TRIM32 tripartite motif containing 32
TRIM38 tripartite motif containing 38
TRIM5 tripartite motif containing 5
TRIM56 tripartite motif containing 56
TTC3 tetratricopeptide repeat domain 3
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2N ubiquitin-conjugating enzyme E2N
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2O ubiquitin-conjugating enzyme E2O
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2S ubiquitin-conjugating enzyme E2S
UBE2T ubiquitin-conjugating enzyme E2T
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE2Z ubiquitin-conjugating enzyme E2Z
UBE3A ubiquitin protein ligase E3A
UBE3C ubiquitin protein ligase E3C
UBE4A ubiquitination factor E4A
UBOX5 U-box domain containing 5
UBR5 ubiquitin protein ligase E3 component n-recognin 5
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFP91 ZFP91 zinc finger protein
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZSWIM2 zinc finger, SWIM-type containing 2