protein polyubiquitination Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain. (Gene Ontology, GO_0000209)
External Link http://amigo.geneontology.org/amigo/term/GO_0000209
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Genes

227 genes participating in the protein polyubiquitination biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AMBRA1 autophagy/beclin-1 regulator 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC13 anaphase promoting complex subunit 13
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANKIB1 ankyrin repeat and IBR domain containing 1
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARRDC4 arrestin domain containing 4
BARD1 BRCA1 associated RING domain 1
BCL2 B-cell CLL/lymphoma 2
BFAR bifunctional apoptosis regulator
BIRC2 baculoviral IAP repeat containing 2
BLMH bleomycin hydrolase
BRCA1 breast cancer 1, early onset
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF90 chromosome 10 open reading frame 90
CBFB core-binding factor, beta subunit
CDC16 cell division cycle 16
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC34 cell division cycle 34
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
CUL3 cullin 3
DAW1 dynein assembly factor with WDR repeat domains 1
DCAF15 DDB1 and CUL4 associated factor 15
DDA1 DET1 and DDB1 associated 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DTX3L deltex 3 like, E3 ubiquitin ligase
DZIP3 DAZ interacting zinc finger protein 3
ERCC8 excision repair cross-complementation group 8
FBXL17 F-box and leucine-rich repeat protein 17
FBXL7 F-box and leucine-rich repeat protein 7
FBXO22 F-box protein 22
FBXO28 F-box protein 28
FBXO38 F-box protein 38
FBXO4 F-box protein 4
FBXO45 F-box protein 45
FBXO7 F-box protein 7
FBXO9 F-box protein 9
FBXW11 F-box and WD repeat domain containing 11
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFI27 interferon, alpha-inducible protein 27
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITCH itchy E3 ubiquitin protein ligase
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KLHL20 kelch-like family member 20
KLHL3 kelch-like family member 3
KLHL42 kelch-like family member 42
LNPEP leucyl/cystinyl aminopeptidase
LOC122513141 ring finger protein-like
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MAGEL2 melanoma antigen family L2
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
MARCHF1 membrane associated ring-CH-type finger 1
MARCHF5 membrane associated ring-CH-type finger 5
MARCHF6 membrane associated ring-CH-type finger 6
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MKRN1 makorin ring finger protein 1
MKRN3 makorin ring finger protein 3
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NHLRC3 NHL repeat containing 3
NPEPPS aminopeptidase puromycin sensitive
NT5C2 5'-nucleotidase, cytosolic II
PARK2 parkin RBR E3 ubiquitin protein ligase
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PELI3 pellino E3 ubiquitin protein ligase family member 3
PEX10 peroxisomal biogenesis factor 10
PEX12 peroxisomal biogenesis factor 12
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRAME preferentially expressed antigen in melanoma
PRPF19 pre-mRNA processing factor 19
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RC3H1 ring finger and CCCH-type domains 1
RC3H2 ring finger and CCCH-type domains 2
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RFPL1 ret finger protein-like 1
RFPL2 ret finger protein-like 2
RFPL3 ret finger protein-like 3
RFPL4A ret finger protein-like 4A
RFPL4AL1 ret finger protein-like 4A-like 1
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF114 ring finger protein 114
RNF115 ring finger protein 115
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126 ring finger protein 126
RNF135 ring finger protein 135
RNF14 ring finger protein 14
RNF144A ring finger protein 144A
RNF144B ring finger protein 144B
RNF146 ring finger protein 146
RNF152 ring finger protein 152
RNF166 ring finger protein 166
RNF167 ring finger protein 167
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF183 ring finger protein 183
RNF185 ring finger protein 185
RNF186 ring finger protein 186
RNF187 ring finger protein 187
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF213 ring finger protein 213
RNF216 ring finger protein 216
RNF217 ring finger protein 217
RNF25 ring finger protein 25
RNF26 ring finger protein 26
RNF31 ring finger protein 31
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RUSC1 RUN and SH3 domain containing 1
SASH1 SAM and SH3 domain containing 1
SHARPIN SHANK-associated RH domain interactor
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPOP speckle-type POZ protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
THOP1 thimet oligopeptidase 1
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPP2 tripeptidyl peptidase II
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF3IP2 TRAF3 interacting protein 2
TRAF4 TNF receptor-associated factor 4
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM2 tripartite motif containing 2
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TRIM27 tripartite motif containing 27
TRIM3 tripartite motif containing 3
TRIM31 tripartite motif containing 31
TRIM32 tripartite motif containing 32
TRIM34 tripartite motif containing 34
TRIM38 tripartite motif containing 38
TRIM45 tripartite motif containing 45
TRIM5 tripartite motif containing 5
TRIM56 tripartite motif containing 56
TRIM58 tripartite motif containing 58
TRIM6 tripartite motif containing 6
TRIM62 tripartite motif containing 62
TRIM65 tripartite motif containing 65
TRIM68 tripartite motif containing 68
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRIM8 tripartite motif containing 8
TRIP12 thyroid hormone receptor interactor 12
TTC3 tetratricopeptide repeat domain 3
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2L5P ubiquitin-conjugating enzyme E2L 5 (pseudogene)
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2N ubiquitin-conjugating enzyme E2N
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBE2O ubiquitin-conjugating enzyme E2O
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2S ubiquitin-conjugating enzyme E2S
UBE2T ubiquitin-conjugating enzyme E2T
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE3A ubiquitin protein ligase E3A
UBE3B ubiquitin protein ligase E3B
UBE3C ubiquitin protein ligase E3C
UBE3D ubiquitin protein ligase E3D
UBE4A ubiquitination factor E4A
UBE4B ubiquitination factor E4B
UBOX5 U-box domain containing 5
UBR5 ubiquitin protein ligase E3 component n-recognin 5
WSB1 WD repeat and SOCS box containing 1
WSB2 WD repeat and SOCS box containing 2
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZFP91 ZFP91 zinc finger protein
ZNF598 zinc finger protein 598
ZNF738 zinc finger protein 738
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase