protein stabilization Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation. (Gene Ontology, GO_0050821)
External Link http://amigo.geneontology.org/amigo/term/GO:0050821
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Genes

213 genes participating in the protein stabilization biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
A1CF APOBEC1 complementation factor
AAK1 AP2 associated kinase 1
AFM afamin
AHSP alpha hemoglobin stabilizing protein
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANK2 ankyrin 2, neuronal
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
ASDURF ASNSD1 upstream open reading frame
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
BAG1 BCL2-associated athanogene
BAG2 BCL2-associated athanogene 2
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BAG5 BCL2-associated athanogene 5
BAG6 BCL2-associated athanogene 6
C10ORF90 chromosome 10 open reading frame 90
CALR calreticulin
CAMLG calcium modulating ligand
CCNH cyclin H
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC37 cell division cycle 37
CDC37L1 cell division cycle 37-like 1
CDK7 cyclin-dependent kinase 7
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP63 centrosomal protein 63kDa
CHEK2 checkpoint kinase 2
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLU clusterin
COA8 cytochrome c oxidase assembly factor 8
COG3 component of oligomeric golgi complex 3
COG7 component of oligomeric golgi complex 7
COPS3 COP9 signalosome subunit 3
CPNE2 copine II
CREB1 cAMP responsive element binding protein 1
CREBL2 cAMP responsive element binding protein-like 2
CRTAP cartilage associated protein
CRYAB crystallin, alpha B
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTNND1 catenin (cadherin-associated protein), delta 1
DNAAF10 dynein axonemal assembly factor 10
DNAAF2 dynein, axonemal, assembly factor 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNLZ DNL-type zinc finger
DSC3 desmocollin 3
DSG1 desmoglein 1
DVL1 dishevelled segment polarity protein 1
DVL3 dishevelled segment polarity protein 3
EFNA1 ephrin-A1
EP300 E1A binding protein p300
EPHA4 EPH receptor A4
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLNA filamin A, alpha
FLOT1 flotillin 1
FLOT2 flotillin 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GET1 guided entry of tail-anchored proteins factor 1
GLMP glycosylated lysosomal membrane protein
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA7 golgin A7
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
GRN granulin
GTPBP4 GTP binding protein 4
H1-5 H1.5 linker histone, cluster member
HCFC1 host cell factor C1
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HPS4 Hermansky-Pudlak syndrome 4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HYPK huntingtin interacting protein K
IFT46 intraflagellar transport 46
IGF1 insulin-like growth factor 1 (somatomedin C)
IRGM immunity-related GTPase family, M
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LOC102724652 alpha-crystallin A chain
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARCHF7 membrane associated ring-CH-type finger 7
MCM8 minichromosome maintenance complex component 8
MDM4 MDM4, p53 regulator
MFSD1 major facilitator superfamily domain containing 1
MORC3 MORC family CW-type zinc finger 3
MSX1 msh homeobox 1
MT3 metallothionein 3
MTMR9 myotubularin related protein 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA30 N(alpha)-acetyltransferase 30, NatC catalytic subunit
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCLN nicalin
NLK nemo-like kinase
NOP53 NOP53 ribosome biogenesis factor
OTUD3 OTU deubiquitinase 3
P3H1 prolyl 3-hydroxylase 1
PAQR4 progestin and adipoQ receptor family member IV
PARK7 parkinson protein 7
PARVA parvin, alpha
PDCD10 programmed cell death 10
PDCL3 phosducin-like 3
PDRG1 p53 and DNA-damage regulated 1
PDZD2 PDZ domain containing 2
PER3 period circadian clock 3
PEX19 peroxisomal biogenesis factor 19
PEX6 peroxisomal biogenesis factor 6
PFDN2 prefoldin subunit 2
PFDN6 prefoldin subunit 6
PFN1 profilin 1
PFN2 profilin 2
PHB1 prohibitin 1
PHB2 prohibitin 2
PIH1D1 PIH1 domain containing 1
PIH1D2 PIH1 domain containing 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PLPP3 phospholipid phosphatase 3
PML promyelocytic leukemia
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRKCD protein kinase C, delta
PRKN parkin RBR E3 ubiquitin protein ligase
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PTEN phosphatase and tensin homolog
PTGES3 prostaglandin E synthase 3 (cytosolic)
PYHIN1 pyrin and HIN domain family, member 1
PYURF PIGY upstream reading frame
RAB21 RAB21, member RAS oncogene family
RABL3 RAB, member of RAS oncogene family-like 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RPAP3 RNA polymerase II associated protein 3
RPL11 ribosomal protein L11
RPL23 ribosomal protein L23
RPL5 ribosomal protein L5
RPS7 ribosomal protein S7
RTN4 reticulon 4
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SAV1 salvador family WW domain containing protein 1
SAXO1 stabilizer of axonemal microtubules 1
SEC16A SEC16 homolog A (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SMAD7 SMAD family member 7
SOX17 SRY (sex determining region Y)-box 17
SOX4 SRY (sex determining region Y)-box 4
SPAG1 sperm associated antigen 1
STK24 serine/threonine kinase 24
STK4 serine/threonine kinase 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX12 syntaxin 12
STXBP4 syntaxin binding protein 4
SUMO1 small ubiquitin-like modifier 1
SWSAP1 SWIM-type zinc finger 7 associated protein 1
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBL1X transducin (beta)-like 1X-linked
TBRG1 transforming growth factor beta regulator 1
TCP1 t-complex 1
TELO2 telomere maintenance 2
TESC tescalcin
TMC6 transmembrane channel-like 6
TMC8 transmembrane channel-like 8
TMEM88 transmembrane protein 88
TNIP2 TNFAIP3 interacting protein 2
TNS1-AS1 TNS1 antisense RNA 1
TRIM37 tripartite motif containing 37
TRIM39 tripartite motif containing 39
TRIM44 tripartite motif containing 44
TSC1 tuberous sclerosis 1
TSPAN1 tetraspanin 1
TTI1 TELO2 interacting protein 1
TTI2 TELO2 interacting protein 2
TYROBP TYRO protein tyrosine kinase binding protein
UBE2B ubiquitin-conjugating enzyme E2B
UFL1 UFM1-specific ligase 1
URI1 URI1, prefoldin-like chaperone
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP19 ubiquitin specific peptidase 19
USP2 ubiquitin specific peptidase 2
USP27X ubiquitin specific peptidase 27, X-linked
USP29 ubiquitin specific peptidase 29
USP33 ubiquitin specific peptidase 33
USP36 ubiquitin specific peptidase 36
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP9X ubiquitin specific peptidase 9, X-linked
UXT ubiquitously-expressed, prefoldin-like chaperone
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR81 WD repeat domain 81
WFS1 Wolfram syndrome 1 (wolframin)
WIZ widely interspaced zinc finger motifs
WNT10B wingless-type MMTV integration site family, member 10B
ZBED3 zinc finger, BED-type containing 3
ZNF207 zinc finger protein 207
ZSWIM7 zinc finger, SWIM-type containing 7