| Dataset | GO Molecular Function Annotations 2023 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links. (Gene Ontology, GO_0003810) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0003810 |
| Similar Terms | |
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8 genes performing the protein-glutamine gamma-glutamyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.
