proteinase Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain. (Gene Ontology, GO_0004175)
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Genes

80 genes co-occuring with the biological term proteinase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACAN aggrecan
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ANXA1 annexin A1
CALR calreticulin
CAPN2 calpain 2, (m/II) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD14 CD14 molecule
CD177 CD177 molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CRTAC1 cartilage acidic protein 1
CRYAA crystallin, alpha A
CRYBA1 crystallin, beta A1
CST3 cystatin C
CST6 cystatin E/M
CTSG cathepsin G
CTSK cathepsin K
CXCL8 chemokine (C-X-C motif) ligand 8
DEFA5 defensin, alpha 5, Paneth cell-specific
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELANE elastase, neutrophil expressed
ERBB4 erb-b2 receptor tyrosine kinase 4
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FN1 fibronectin 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMM granzyme M (lymphocyte met-ase 1)
IL18 interleukin 18
IL32 interleukin 32
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KLF5 Kruppel-like factor 5 (intestinal)
KLK3 kallikrein-related peptidase 3
LCN1 lipocalin 1
LTF lactotransferrin
LYZ lysozyme
MAPK1 mitogen-activated protein kinase 1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NFE2L2 nuclear factor, erythroid 2-like 2
PABPC1 poly(A) binding protein, cytoplasmic 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PCBP2 poly(rC) binding protein 2
PCOLCE procollagen C-endopeptidase enhancer
PI3 peptidase inhibitor 3, skin-derived
PIP prolactin-induced protein
PITRM1 pitrilysin metallopeptidase 1
PLAU plasminogen activator, urokinase
PLCG1 phospholipase C, gamma 1
PRNP prion protein
PRSS1 protease, serine, 1 (trypsin 1)
PRTN3 proteinase 3
PSEN1 presenilin 1
PTBP1 polypyrimidine tract binding protein 1
PTK7 protein tyrosine kinase 7 (inactive)
RHOA ras homolog family member A
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLPI secretory leukocyte peptidase inhibitor
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
TGFBR3 transforming growth factor, beta receptor III
TIMP1 TIMP metallopeptidase inhibitor 1
TMPRSS11E transmembrane protease, serine 11E
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
WT1 Wilms tumor 1