proteoglycan Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A glycoprotein in which the carbohydrate units are polysaccharides that contain amino sugars. The protein is glycosylated by one or more (up to about 100) glycosaminoglycans. (Chemical Entities of Biological Interest Ontology, CHEBI_37396)
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Genes

77 genes co-occuring with the biological term proteoglycan in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAN aggrecan
ACTN1 actinin, alpha 1
ADAM28 ADAM metallopeptidase domain 28
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRE5 adhesion G protein-coupled receptor E5
AGRN agrin
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BCAN brevican
BGN biglycan
CANT1 calcium activated nucleotidase 1
CD44 CD44 molecule (Indian blood group)
COL15A1 collagen, type XV, alpha 1
COL18A1 collagen, type XVIII, alpha 1
CSPG4 chondroitin sulfate proteoglycan 4
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DCN decorin
EFNB3 ephrin-B3
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
FBLN1 fibulin 1
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
GDF5 growth differentiation factor 5
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPC3 glypican 3
GPC6 glypican 6
HAPLN1 hyaluronan and proteoglycan link protein 1
HPSE heparanase
HSPG2 heparan sulfate proteoglycan 2
IL1R1 interleukin 1 receptor, type I
IL6 interleukin 6
IL6R interleukin 6 receptor
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LGALS3 lectin, galactoside-binding, soluble, 3
LUM lumican
M6PR mannose-6-phosphate receptor (cation dependent)
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK14 mitogen-activated protein kinase 14
MIR633 microRNA 633
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP9 matrix metallopeptidase 9
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OGN osteoglycin
OPRK1 opioid receptor, kappa 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG3 paternally expressed 3
PRKCA protein kinase C, alpha
SDC1 syndecan 1
SDC2 syndecan 2
SDC4 syndecan 4
SELL selectin L
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMC3 structural maintenance of chromosomes 3
SRGN serglycin
SRPX2 sushi-repeat containing protein, X-linked 2
SULF1 sulfatase 1
SULF2 sulfatase 2
TGFBR1 transforming growth factor, beta receptor 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
UXS1 UDP-glucuronate decarboxylase 1
VCAN versican
VEGFA vascular endothelial growth factor A
XYLT1 xylosyltransferase I
XYLT2 xylosyltransferase II