proteolysis involved in protein catabolic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. (Gene Ontology, GO_0051603)
External Link http://amigo.geneontology.org/amigo/term/GO_0051603
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Genes

79 genes participating in the proteolysis involved in protein catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATE1 arginyltransferase 1
ATXN3 ataxin 3
BAG6 BCL2-associated athanogene 6
CAPN2 calpain 2, (m/II) large subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CEL carboxyl ester lipase
CHMP4A charged multivesicular body protein 4A
CHMP4C charged multivesicular body protein 4C
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CTSB cathepsin B
CTSC cathepsin C
CTSF cathepsin F
CTSH cathepsin H
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CTSV cathepsin V
CTSW cathepsin W
CTSZ cathepsin Z
CUL4B cullin 4B
DDB1 damage-specific DNA binding protein 1, 127kDa
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DTX4 deltex 4, E3 ubiquitin ligase
FBXL17 F-box and leucine-rich repeat protein 17
FBXO44 F-box protein 44
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HDAC6 histone deacetylase 6
HM13 histocompatibility (minor) 13
IDE insulin-degrading enzyme
ISG15 ISG15 ubiquitin-like modifier
LGMN legumain
LONP1 lon peptidase 1, mitochondrial
MALT1 MALT1 paracaspase
MARCHF6 membrane associated ring-CH-type finger 6
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NGLY1 N-glycanase 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
OMA1 OMA1 zinc metallopeptidase
OTUD7A OTU deubiquitinase 7A
OTUD7B OTU deubiquitinase 7B
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD6IP programmed cell death 6 interacting protein
PEX10 peroxisomal biogenesis factor 10
PEX12 peroxisomal biogenesis factor 12
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRPF19 pre-mRNA processing factor 19
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
RHBDD1 rhomboid domain containing 1
RNF123 ring finger protein 123
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
RPS27AP5 ribosomal protein S27a pseudogene 5
RSPRY1 ring finger and SPRY domain containing 1
SOCS6 suppressor of cytokine signaling 6
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIM21 tripartite motif containing 21
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBE2W ubiquitin-conjugating enzyme E2W (putative)
USP17L24 ubiquitin specific peptidase 17-like family member 24
USP17L6P ubiquitin specific peptidase 17-like family member 6, pseudogene
USP28 ubiquitin specific peptidase 28
USP9X ubiquitin specific peptidase 9, X-linked
VCP valosin containing protein
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
YME1L1 YME1-like 1 ATPase
ZER1 zyg-11 related, cell cycle regulator
ZRANB1 zinc finger, RAN-binding domain containing 1
ZYG11B zyg-11 family member B, cell cycle regulator