proteolysis Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. (Gene Ontology, GO_0006508)
External Link http://amigo.geneontology.org/amigo/term/GO:0006508
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Genes

896 genes participating in the proteolysis biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACR acrosin
ACY1 aminoacylase 1
ADAM10 ADAM metallopeptidase domain 10
ADAM11 ADAM metallopeptidase domain 11
ADAM12 ADAM metallopeptidase domain 12
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ADAM18 ADAM metallopeptidase domain 18
ADAM19 ADAM metallopeptidase domain 19
ADAM2 ADAM metallopeptidase domain 2
ADAM20 ADAM metallopeptidase domain 20
ADAM21 ADAM metallopeptidase domain 21
ADAM22 ADAM metallopeptidase domain 22
ADAM23 ADAM metallopeptidase domain 23
ADAM28 ADAM metallopeptidase domain 28
ADAM29 ADAM metallopeptidase domain 29
ADAM30 ADAM metallopeptidase domain 30
ADAM32 ADAM metallopeptidase domain 32
ADAM33 ADAM metallopeptidase domain 33
ADAM7 ADAM metallopeptidase domain 7
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADAMDEC1 ADAM-like, decysin 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADAMTSL1 ADAMTS-like 1
ADAMTSL2 ADAMTS-like 2
ADAMTSL3 ADAMTS-like 3
ADAMTSL4 ADAMTS-like 4
ADAMTSL5 ADAMTS-like 5
ADGB androglobin
AEBP1 AE binding protein 1
AFG3L2 AFG3-like AAA ATPase 2
AGA aspartylglucosaminidase
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGBL1 ATP/GTP binding protein-like 1
AGBL2 ATP/GTP binding protein-like 2
AGBL3 ATP/GTP binding protein-like 3
AGBL4 ATP/GTP binding protein-like 4
AGBL5 ATP/GTP binding protein-like 5
AGTPBP1 ATP/GTP binding protein 1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMZ1 archaelysin family metallopeptidase 1
AMZ2 archaelysin family metallopeptidase 2
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANPEP alanyl (membrane) aminopeptidase
APC adenomatous polyposis coli
APEH acylaminoacyl-peptide hydrolase
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASPRV1 aspartic peptidase, retroviral-like 1
ASRGL1 asparaginase like 1
ASTL astacin-like metallo-endopeptidase (M12 family)
ATG4A autophagy related 4A, cysteine peptidase
ATG4B autophagy related 4B, cysteine peptidase
ATG4C autophagy related 4C, cysteine peptidase
ATG4D autophagy related 4D, cysteine peptidase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATXN3 ataxin 3
ATXN3L ataxin 3-like
AURKA aurora kinase A
AURKB aurora kinase B
AZU1 azurocidin 1
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
BAG6 BCL2-associated athanogene 6
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BFAR bifunctional apoptosis regulator
BIRC2 baculoviral IAP repeat containing 2
BLMH bleomycin hydrolase
BMP1 bone morphogenetic protein 1
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
C19ORF68 chromosome 19 open reading frame 68
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
C1S complement component 1, s subcomponent
C2 complement component 2
C2ORF40 chromosome 2 open reading frame 40
C9ORF3 chromosome 9 open reading frame 3
CACUL1 CDK2-associated, cullin domain 1
CAPN1 calpain 1, (mu/I) large subunit
CAPN10 calpain 10
CAPN11 calpain 11
CAPN12 calpain 12
CAPN13 calpain 13
CAPN14 calpain 14
CAPN15 calpain 15
CAPN2 calpain 2, (m/II) large subunit
CAPN3 calpain 3, (p94)
CAPN5 calpain 5
CAPN6 calpain 6
CAPN7 calpain 7
CAPN8 calpain 8
CAPN9 calpain 9
CAPNS1 calpain, small subunit 1
CAPNS2 calpain, small subunit 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP12 caspase 12 (gene/pseudogene)
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNB1 cyclin B1
CCNF cyclin F
CD46 CD46 molecule, complement regulatory protein
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC34 cell division cycle 34
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CELA1 chymotrypsin-like elastase family, member 1
CELA2A chymotrypsin-like elastase family, member 2A
CELA2B chymotrypsin-like elastase family, member 2B
CELA3A chymotrypsin-like elastase family, member 3A
CELA3B chymotrypsin-like elastase family, member 3B
CFB complement factor B
CFD complement factor D (adipsin)
CFI complement factor I
CFLAR CASP8 and FADD-like apoptosis regulator
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHMP1A charged multivesicular body protein 1A
CHMP4B charged multivesicular body protein 4B
CHMP4C charged multivesicular body protein 4C
CIT citron rho-interacting serine/threonine kinase
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CLCA4 chloride channel accessory 4
CLOCK clock circadian regulator
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CMA1 chymase 1, mast cell
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
COPS3 COP9 signalosome subunit 3
COPS5 COP9 signalosome subunit 5
CORIN corin, serine peptidase
CPA1 carboxypeptidase A1 (pancreatic)
CPA2 carboxypeptidase A2 (pancreatic)
CPA3 carboxypeptidase A3 (mast cell)
CPA4 carboxypeptidase A4
CPA5 carboxypeptidase A5
CPA6 carboxypeptidase A6
CPB1 carboxypeptidase B1 (tissue)
CPB2 carboxypeptidase B2 (plasma)
CPD carboxypeptidase D
CPE carboxypeptidase E
CPM carboxypeptidase M
CPN1 carboxypeptidase N, polypeptide 1
CPO carboxypeptidase O
CPQ carboxypeptidase Q
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CPVL carboxypeptidase, vitellogenic-like
CPXM1 carboxypeptidase X (M14 family), member 1
CPXM2 carboxypeptidase X (M14 family), member 2
CPZ carboxypeptidase Z
CRBN cereblon
CTRB2 chymotrypsinogen B2
CTRC chymotrypsin C (caldecrin)
CTRL chymotrypsin-like
CTSA cathepsin A
CTSB cathepsin B
CTSC cathepsin C
CTSD cathepsin D
CTSE cathepsin E
CTSF cathepsin F
CTSG cathepsin G
CTSH cathepsin H
CTSK cathepsin K
CTSL cathepsin L
CTSO cathepsin O
CTSS cathepsin S
CTSV cathepsin V
CTSW cathepsin W
CTSZ cathepsin Z
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL4A cullin 4A
CUL4B cullin 4B
CUL5 cullin 5
CUL7 cullin 7
CUL9 cullin 9
CYLD cylindromatosis (turban tumor syndrome)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCD dermcidin
DDB1 damage-specific DNA binding protein 1, 127kDa
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DDIT3 DNA-damage-inducible transcript 3
DERL1 derlin 1
DERL2 derlin 2
DERL3 derlin 3
DESI1 desumoylating isopeptidase 1
DESI2 desumoylating isopeptidase 2
DHH desert hedgehog
DLD dihydrolipoamide dehydrogenase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNPEP aspartyl aminopeptidase
DPEP1 dipeptidase 1 (renal)
DPEP2 dipeptidase 2
DPEP3 dipeptidase 3
DPP10 dipeptidyl-peptidase 10 (non-functional)
DPP3 dipeptidyl-peptidase 3
DPP4 dipeptidyl-peptidase 4
DPP6 dipeptidyl-peptidase 6
DPP7 dipeptidyl-peptidase 7
DPP8 dipeptidyl-peptidase 8
DPP9 dipeptidyl-peptidase 9
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ECE1 endothelin converting enzyme 1
ECE2 endothelin converting enzyme 2
ECEL1 endothelin converting enzyme-like 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EIF3F eukaryotic translation initiation factor 3, subunit F
ELANE elastase, neutrophil expressed
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENDOU endonuclease, polyU-specific
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC8 excision repair cross-complementation group 8
ERLIN1 ER lipid raft associated 1
ERLIN2 ER lipid raft associated 2
ERMP1 endoplasmic reticulum metallopeptidase 1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
F10 coagulation factor X
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FAF1 Fas (TNFRSF6) associated factor 1
FAM76B family with sequence similarity 76, member B
FAP fibroblast activation protein, alpha
FBXL12 F-box and leucine-rich repeat protein 12
FBXL15 F-box and leucine-rich repeat protein 15
FBXL19 F-box and leucine-rich repeat protein 19
FBXL2 F-box and leucine-rich repeat protein 2
FBXL3 F-box and leucine-rich repeat protein 3
FBXL4 F-box and leucine-rich repeat protein 4
FBXL5 F-box and leucine-rich repeat protein 5
FBXL6 F-box and leucine-rich repeat protein 6
FBXL7 F-box and leucine-rich repeat protein 7
FBXO11 F-box protein 11
FBXO2 F-box protein 2
FBXO21 F-box protein 21
FBXO22 F-box protein 22
FBXO3 F-box protein 3
FBXO31 F-box protein 31
FBXO4 F-box protein 4
FBXO45 F-box protein 45
FBXO5 F-box protein 5
FBXO6 F-box protein 6
FBXO7 F-box protein 7
FBXO8 F-box protein 8
FBXO9 F-box protein 9
FBXW11 F-box and WD repeat domain containing 11
FBXW2 F-box and WD repeat domain containing 2
FBXW4 F-box and WD repeat domain containing 4
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW9 F-box and WD repeat domain containing 9
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLH1B folate hydrolase 1B
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FURIN furin (paired basic amino acid cleaving enzyme)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAS6 growth arrest-specific 6
GCA grancalcin, EF-hand calcium binding protein
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GGT1 gamma-glutamyltransferase 1
GGT5 gamma-glutamyltransferase 5
GGT6 gamma-glutamyltransferase 6
GGT7 gamma-glutamyltransferase 7
GSK3A glycogen synthase kinase 3 alpha
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
GZMK granzyme K (granzyme 3; tryptase II)
GZMM granzyme M (lymphocyte met-ase 1)
HABP2 hyaluronan binding protein 2
HDAC6 histone deacetylase 6
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGFAC HGF activator
HM13 histocompatibility (minor) 13
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HPN hepsin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
HTRA3 HtrA serine peptidase 3
HTRA4 HtrA serine peptidase 4
IDE insulin-degrading enzyme
IHH indian hedgehog
IMMP1L IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
ISG15 ISG15 ubiquitin-like modifier
ITCH itchy E3 ubiquitin protein ligase
JKAMP JNK1/MAPK8-associated membrane protein
JOSD1 Josephin domain containing 1
JOSD2 Josephin domain containing 2
KAT5 K(lysine) acetyltransferase 5
KCTD10 potassium channel tetramerization domain containing 10
KCTD13 potassium channel tetramerization domain containing 13
KEAP1 kelch-like ECH-associated protein 1
KEL Kell blood group, metallo-endopeptidase
KIAA0368 KIAA0368
KIF14 kinesin family member 14
KLHL20 kelch-like family member 20
KLHL42 kelch-like family member 42
KLK1 kallikrein 1
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
KLK12 kallikrein-related peptidase 12
KLK13 kallikrein-related peptidase 13
KLK14 kallikrein-related peptidase 14
KLK15 kallikrein-related peptidase 15
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KLK4 kallikrein-related peptidase 4
KLK5 kallikrein-related peptidase 5
KLK6 kallikrein-related peptidase 6
KLK7 kallikrein-related peptidase 7
KLK8 kallikrein-related peptidase 8
KLK9 kallikrein-related peptidase 9
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KY kyphoscoliosis peptidase
LAP3 leucine aminopeptidase 3
LCN1 lipocalin 1
LGMN legumain
LMLN leishmanolysin-like (metallopeptidase M8 family)
LNPEP leucyl/cystinyl aminopeptidase
LONP1 lon peptidase 1, mitochondrial
LONP2 lon peptidase 2, peroxisomal
LONRF1 LON peptidase N-terminal domain and ring finger 1
LONRF2 LON peptidase N-terminal domain and ring finger 2
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LTA4H leukotriene A4 hydrolase
LTF lactotransferrin
LVRN laeverin
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MALT1 MALT1 paracaspase
MAN1B1 mannosidase, alpha, class 1B, member 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEP1A meprin A, alpha (PABA peptide hydrolase)
MEP1B meprin A, beta
METAP1 methionyl aminopeptidase 1
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
METAP2 methionyl aminopeptidase 2
MIPEP mitochondrial intermediate peptidase
MME membrane metallo-endopeptidase
MMEL1 membrane metallo-endopeptidase-like 1
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP20 matrix metallopeptidase 20
MMP21 matrix metallopeptidase 21
MMP23B matrix metallopeptidase 23B
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MMP26 matrix metallopeptidase 26
MMP27 matrix metallopeptidase 27
MMP28 matrix metallopeptidase 28
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPND MPN domain containing
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
MTA1 metastasis associated 1
MVB12A multivesicular body subunit 12A
MVB12B multivesicular body subunit 12B
MYH9 myosin, heavy chain 9, non-muscle
MYRF myelin regulatory factor
MYSM1 Myb-like, SWIRM and MPN domains 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NAPSA napsin A aspartic peptidase
NCSTN nicastrin
NDEL1 nudE neurodevelopment protein 1-like 1
NDFIP1 Nedd4 family interacting protein 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEK2 NIMA-related kinase 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NLN neurolysin (metallopeptidase M3 family)
NPEPL1 aminopeptidase-like 1
NPEPPS aminopeptidase puromycin sensitive
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRD1 nardilysin (N-arginine dibasic convertase)
NRIP2 nuclear receptor interacting protein 2
NRIP3 nuclear receptor interacting protein 3
NSFL1C NSFL1 (p97) cofactor (p47)
NUB1 negative regulator of ubiquitin-like proteins 1
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OMA1 OMA1 zinc metallopeptidase
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OTUD1 OTU deubiquitinase 1
OTUD3 OTU deubiquitinase 3
OTUD4 OTU deubiquitinase 4
OTUD5 OTU deubiquitinase 5
OTUD6A OTU deubiquitinase 6A
OTUD6B OTU domain containing 6B
OTUD7A OTU deubiquitinase 7A
OTUD7B OTU deubiquitinase 7B
OTULIN OTU deubiquitinase with linear linkage specificity
OVCH1 ovochymase 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P4HB prolyl 4-hydroxylase, beta polypeptide
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPPA2 pappalysin 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARL presenilin associated, rhomboid-like
PCBP2 poly(rC) binding protein 2
PCNP PEST proteolytic signal containing nuclear protein
PCOLCE procollagen C-endopeptidase enhancer
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PCSK4 proprotein convertase subtilisin/kexin type 4
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PCSK9 proprotein convertase subtilisin/kexin type 9
PCYOX1 prenylcysteine oxidase 1
PCYOX1L prenylcysteine oxidase 1 like
PDCD6 programmed cell death 6
PDCD6IP programmed cell death 6 interacting protein
PDIA3 protein disulfide isomerase family A, member 3
PEF1 penta-EF-hand domain containing 1
PEPD peptidase D
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PGC progastricsin (pepsinogen C)
PGPEP1 pyroglutamyl-peptidase I
PGPEP1L pyroglutamyl-peptidase I-like
PHEX phosphate regulating endopeptidase homolog, X-linked
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PINK1 PTEN induced putative kinase 1
PIP prolactin-induced protein
PITRM1 pitrilysin metallopeptidase 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLG plasminogen
PLK1 polo-like kinase 1
PM20D1 peptidase M20 domain containing 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PMPCA peptidase (mitochondrial processing) alpha
PMPCB peptidase (mitochondrial processing) beta
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRCP prolylcarboxypeptidase (angiotensinase C)
PREP prolyl endopeptidase
PREPL prolyl endopeptidase-like
PRKCQ protein kinase C, theta
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRPF19 pre-mRNA processing factor 19
PRSS1 protease, serine, 1 (trypsin 1)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS16 protease, serine, 16 (thymus)
PRSS2 protease, serine, 2 (trypsin 2)
PRSS21 protease, serine, 21 (testisin)
PRSS22 protease, serine, 22
PRSS27 protease, serine 27
PRSS3 protease, serine, 3
PRSS33 protease, serine, 33
PRSS36 protease, serine, 36
PRSS37 protease, serine, 37
PRSS38 protease, serine, 38
PRSS41 protease, serine, 41
PRSS42 protease, serine, 42
PRSS45 protease, serine, 45
PRSS46 protease, serine, 46
PRSS48 protease, serine, 48
PRSS50 protease, serine, 50
PRSS53 protease, serine, 53
PRSS54 protease, serine, 54
PRSS55 protease, serine, 55
PRSS56 protease, serine, 56
PRSS57 protease, serine, 57
PRSS58 protease, serine, 58
PRSS8 protease, serine, 8
PRTN3 proteinase 3
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTTG1 pituitary tumor-transforming 1
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBMX RNA binding motif protein, X-linked
RBP3 retinol binding protein 3, interstitial
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCE1 Ras converting CAAX endopeptidase 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELN reelin
REN renin
RET ret proto-oncogene
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RHBDD1 rhomboid domain containing 1
RHBDD2 rhomboid domain containing 2
RHBDD3 rhomboid domain containing 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHBDL1 rhomboid, veinlet-like 1 (Drosophila)
RHBDL2 rhomboid, veinlet-like 2 (Drosophila)
RHBDL3 rhomboid, veinlet-like 3 (Drosophila)
RLIM ring finger protein, LIM domain interacting
RNF103 ring finger protein 103
RNF111 ring finger protein 111
RNF115 ring finger protein 115
RNF121 ring finger protein 121
RNF126 ring finger protein 126
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF175 ring finger protein 175
RNF187 ring finger protein 187
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RNF216 ring finger protein 216
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RNPEP arginyl aminopeptidase (aminopeptidase B)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPS27A ribosomal protein S27a
SCPEP1 serine carboxypeptidase 1
SCRN1 secernin 1
SCRN2 secernin 2
SCRN3 secernin 3
SDF2L1 stromal cell-derived factor 2-like 1
SEC11A SEC11 homolog A (S. cerevisiae)
SEC11C SEC11 homolog C (S. cerevisiae)
SEC61B Sec61 beta subunit
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SENP1 SUMO1/sentrin specific peptidase 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SENP5 SUMO1/sentrin specific peptidase 5
SENP6 SUMO1/sentrin specific peptidase 6
SENP7 SUMO1/sentrin specific peptidase 7
SENP8 SUMO/sentrin specific peptidase family member 8
SFRP1 secreted frizzled-related protein 1
SHH sonic hedgehog
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIAH3 siah E3 ubiquitin protein ligase family member 3
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOCS6 suppressor of cytokine signaling 6
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SPOP speckle-type POZ protein
SPOPL speckle-type POZ protein-like
SPPL2A signal peptide peptidase like 2A
SPPL2B signal peptide peptidase like 2B
SPPL2C signal peptide peptidase like 2C
SPPL3 signal peptide peptidase like 3
SQSTM1 sequestosome 1
SRI sorcin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAMBP STAM binding protein
STAMBPL1 STAM binding protein-like 1
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUFU suppressor of fused homolog (Drosophila)
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TASP1 taspase, threonine aspartase, 1
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TENM3 teneurin transmembrane protein 3
TENM4 teneurin transmembrane protein 4
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THOP1 thimet oligopeptidase 1
THSD4 thrombospondin, type I, domain containing 4
TINAG tubulointerstitial nephritis antigen
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLL1 tolloid-like 1
TLL2 tolloid-like 2
TMEM27 transmembrane protein 27
TMEM59 transmembrane protein 59
TMEM67 transmembrane protein 67
TMPRSS11A transmembrane protease, serine 11A
TMPRSS11B transmembrane protease, serine 11B
TMPRSS11D transmembrane protease, serine 11D
TMPRSS11E transmembrane protease, serine 11E
TMPRSS11F transmembrane protease, serine 11F
TMPRSS12 transmembrane (C-terminal) protease, serine 12
TMPRSS13 transmembrane protease, serine 13
TMPRSS15 transmembrane protease, serine 15
TMPRSS2 transmembrane protease, serine 2
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TMPRSS5 transmembrane protease, serine 5
TMPRSS6 transmembrane protease, serine 6
TMPRSS7 transmembrane protease, serine 7
TMPRSS9 transmembrane protease, serine 9
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOM1L1 target of myb1 (chicken)-like 1
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TOR1A torsin family 1, member A (torsin A)
TPP1 tripeptidyl peptidase I
TPP2 tripeptidyl peptidase II
TPSAB1 tryptase alpha/beta 1
TPSD1 tryptase delta 1
TPSG1 tryptase gamma 1
TRABD2A TraB domain containing 2A
TRABD2B TraB domain containing 2B
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC12 trafficking protein particle complex 12
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM13 tripartite motif containing 13
TRIM38 tripartite motif containing 38
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIM9 tripartite motif containing 9
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSG101 tumor susceptibility 101
TTC3 tetratricopeptide repeat domain 3
TYSND1 trypsin domain containing 1
UBA1 ubiquitin-like modifier activating enzyme 1
UBA3 ubiquitin-like modifier activating enzyme 3
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA6 ubiquitin-like modifier activating enzyme 6
UBA7 ubiquitin-like modifier activating enzyme 7
UBAP1 ubiquitin associated protein 1
UBB ubiquitin B
UBC ubiquitin C
UBD ubiquitin D
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2I ubiquitin-conjugating enzyme E2I
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2N ubiquitin-conjugating enzyme E2N
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2S ubiquitin-conjugating enzyme E2S
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE3A ubiquitin protein ligase E3A
UBE4A ubiquitination factor E4A
UBE4B ubiquitination factor E4B
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UBXN1 UBX domain protein 1
UBXN11 UBX domain protein 11
UBXN2A UBX domain protein 2A
UBXN2B UBX domain protein 2B
UBXN8 UBX domain protein 8
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UFD1L ubiquitin fusion degradation 1 like (yeast)
UFSP1 UFM1-specific peptidase 1 (non-functional)
UFSP2 UFM1-specific peptidase 2
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
UNC5CL unc-5 homolog C (C. elegans)-like
UQCRC2 ubiquinol-cytochrome c reductase core protein II
USP1 ubiquitin specific peptidase 1
USP10 ubiquitin specific peptidase 10
USP11 ubiquitin specific peptidase 11
USP12 ubiquitin specific peptidase 12
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP15 ubiquitin specific peptidase 15
USP16 ubiquitin specific peptidase 16
USP17L1 ubiquitin specific peptidase 17-like family member 1
USP17L10 ubiquitin specific peptidase 17-like family member 10
USP17L11 ubiquitin specific peptidase 17-like family member 11
USP17L12 ubiquitin specific peptidase 17-like family member 12
USP17L13 ubiquitin specific peptidase 17-like family member 13
USP17L17 ubiquitin specific peptidase 17-like family member 17
USP17L18 ubiquitin specific peptidase 17-like family member 18
USP17L19 ubiquitin specific peptidase 17-like family member 19
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP17L20 ubiquitin specific peptidase 17-like family member 20
USP17L21 ubiquitin specific peptidase 17-like family member 21
USP17L22 ubiquitin specific peptidase 17-like family member 22
USP17L3 ubiquitin specific peptidase 17-like family member 3
USP17L4 ubiquitin specific peptidase 17-like family member 4
USP17L5 ubiquitin specific peptidase 17-like family member 5
USP17L7 ubiquitin specific peptidase 17-like family member 7
USP17L8 ubiquitin specific peptidase 17-like family member 8
USP18 ubiquitin specific peptidase 18
USP19 ubiquitin specific peptidase 19
USP2 ubiquitin specific peptidase 2
USP20 ubiquitin specific peptidase 20
USP21 ubiquitin specific peptidase 21
USP22 ubiquitin specific peptidase 22
USP24 ubiquitin specific peptidase 24
USP25 ubiquitin specific peptidase 25
USP26 ubiquitin specific peptidase 26
USP27X ubiquitin specific peptidase 27, X-linked
USP28 ubiquitin specific peptidase 28
USP29 ubiquitin specific peptidase 29
USP3 ubiquitin specific peptidase 3
USP30 ubiquitin specific peptidase 30
USP31 ubiquitin specific peptidase 31
USP32 ubiquitin specific peptidase 32
USP33 ubiquitin specific peptidase 33
USP34 ubiquitin specific peptidase 34
USP35 ubiquitin specific peptidase 35
USP36 ubiquitin specific peptidase 36
USP37 ubiquitin specific peptidase 37
USP38 ubiquitin specific peptidase 38
USP39 ubiquitin specific peptidase 39
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP40 ubiquitin specific peptidase 40
USP42 ubiquitin specific peptidase 42
USP43 ubiquitin specific peptidase 43
USP44 ubiquitin specific peptidase 44
USP45 ubiquitin specific peptidase 45
USP46 ubiquitin specific peptidase 46
USP47 ubiquitin specific peptidase 47
USP48 ubiquitin specific peptidase 48
USP49 ubiquitin specific peptidase 49
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP50 ubiquitin specific peptidase 50
USP51 ubiquitin specific peptidase 51
USP53 ubiquitin specific peptidase 53
USP54 ubiquitin specific peptidase 54
USP6 ubiquitin specific peptidase 6
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
USP9Y ubiquitin specific peptidase 9, Y-linked
USPL1 ubiquitin specific peptidase like 1
VCP valosin containing protein
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIMP VCP-interacting membrane selenoprotein
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
WFS1 Wolfram syndrome 1 (wolframin)
WNT1 wingless-type MMTV integration site family, member 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
WWTR1 WW domain containing transcription regulator 1
XBP1 X-box binding protein 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC6BP1 XRCC6 binding protein 1
YBEY ybeY metallopeptidase (putative)
YME1L1 YME1-like 1 ATPase
YOD1 YOD1 deubiquitinase
ZFYVE9 zinc finger, FYVE domain containing 9
ZMPSTE24 zinc metallopeptidase STE24
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZNRF3 zinc and ring finger 3