| Dataset | GO Cellular Component Annotations |
| Category | structural or functional annotations |
| Type | cellular component |
| Description | A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane. (Gene Ontology, GO_0033176) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0033176 |
| Similar Terms | |
| Downloads & Tools |
12 proteins localized to the proton-transporting v-type atpase complex cellular component from the curated GO Cellular Component Annotations dataset.
| Symbol | Name |
|---|---|
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 |
| ATP6V0D2 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| ATP6V1F | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| ATP6V1G3 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
