A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A. (Gene Ontology, GO_0033180)
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9 proteins localized to the proton-transporting v-type atpase, v1 domain cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.